Acid-PEG4-S-S-PEG4-Acid

Product Name: Acid-PEG4-S-S-PEG4-Acid
CAS No.: 2055015-40-0
Chemical Name: Acid-PEG4-S-S-PEG4-Acid
Synonyms: Acid-PEG4-S-S-PEG4-Acid;4,7,10,13,20,23,26,29-Octaoxa-16,17-dithiadotriacontanedioic acid
CBNumber: CB73363833
Molecular Formula: C22H42O12S2
Formula Weight: 562.69
MOL File: 2055015-40-0.mol

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Acid-PEG4-S-S-PEG4-Acid Property

Boiling point:: 683.6±55.0 °C(Predicted)
Density: 1.223±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, stored under nitrogen
form: Liquid
pka: 3.97±0.10(Predicted)
color: Light yellow to brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22786
Product name: Acid-PEG4-S-S-PEG4-acid
Purity: 98%
Packaging: 100mg
Price: $280
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1006
Product name: Acid-PEG4-S-S-PEG4-Acid
Packaging: 100mg
Price: $546
Updated: 2021/12/16

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Acid-PEG4-S-S-PEG4-Acid Chemical Properties,Usage,Production

Description

Acid-PEG4-SS-PEG4-acid is a homobifunctional cleavable linker with carboxylic acid groups at both sides. The terminal carboxylic acids can be reacted with primary amines in the presences of activators such as EDC and HATU to form stable amide bonds. The disulfide bonds can be cleaved by using Dithiothreitol (DTT) reagent.

Uses

Acid-PEG4-S-S-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acid-PEG4-S-S-PEG4-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Acid-PEG4-S-S-PEG4-Acid Suppliers

China 18 United Kingdom 1 United States 4 Global 23

Jinan elephant international trading co., LTD

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View Lastest Price from Acid-PEG4-S-S-PEG4-Acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Acid-PEG4-S-S-PEG4-acid 2055015-40-0
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-23

2055015-40-0, Acid-PEG4-S-S-PEG4-AcidRelated Search:

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Acid-PEG4-S-S-PEG4-Acid

4,7,10,13,20,23,26,29-Octaoxa-16,17-dithiadotriacontanedioic acid

2055015-40-0

C22H42O12S2