ChemicalBook > CAS DataBase List > 4'-Methyl-2-cyanobiphenyl

4'-Methyl-2-cyanobiphenyl

Product Name
4'-Methyl-2-cyanobiphenyl
CAS No.
114772-53-1
Chemical Name
4'-Methyl-2-cyanobiphenyl
Synonyms
OTBN;2-Cyano-4'-methylbiphenyl;2MPPC;AKOS BAR-1203;Sartandiphenyl;Sartanbiphenyl;methyl diphenyl;-2-cyanobiphenyL;2-tolylbenzonitrile;2-hexylbenzonitrile
CBNumber
CB7337004
Molecular Formula
C14H11N
Formula Weight
193.24
MOL File
114772-53-1.mol
More
Less

4'-Methyl-2-cyanobiphenyl Property

Melting point:
49 °C
Boiling point:
>320°C
Density 
1,17 g/cm3
vapor pressure 
0.014Pa at 20℃
Flash point:
>320°C
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline Powder
color 
Off-white to beige
BRN 
3605954
LogP
3.5 at 23℃
CAS DataBase Reference
114772-53-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzonitrile, 2-(4-methylphenyl)-(114772-53-1)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38-48/25/62/51/53-22
Safety Statements 
22-26-36/37/39-36/37/45/57-20-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
27075000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H313May be harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
C1446
Product name
2-Cyano-4'-methylbiphenyl
Purity
>99.0%(GC)
Packaging
10g
Price
$37
Updated
2024/03/01
Alfa Aesar
Product number
B21273
Product name
2-Cyano-4'-methylbiphenyl, 98+%
Packaging
5g
Price
$50.8
Updated
2024/03/01
Alfa Aesar
Product number
B21273
Product name
2-Cyano-4'-methylbiphenyl, 98+%
Packaging
25g
Price
$162
Updated
2024/03/01
Alfa Aesar
Product number
B21273
Product name
2-Cyano-4'-methylbiphenyl, 98+%
Packaging
100g
Price
$431
Updated
2024/03/01
TRC
Product number
M294115
Product name
4''-Methylbiphenyl-2-carbonitrile
Packaging
25g
Price
$185
Updated
2021/12/16
More
Less

4'-Methyl-2-cyanobiphenyl Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.

Synthesis

4'-Methyl-2-cyanobiphenyl is prepared by the reaction of o-cyanobromobenzene and potassium (4-methylphenyl)trifluoroborate. The specific synthesis steps are as follows:
General procedure: A mixture of aryl halide (0.5 mmol), potassium aryltrifluoroborate (0.6 mmol), K2CO3 (1.0 mmol), Pd/C (5%; 0.5 mol%), ethanol (3 mL), and distilled water (1 mL) was stirred at 80 °C in air for the time indicated. The reaction mixture was added to brine (15 mL) and extracted with ethyl acetate (4×15 mL). The organic solvent was removed under vacuum, and the product was isolated by short-column chromatography.

4'-Methyl-2-cyanobiphenyl Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4'-Methyl-2-cyanobiphenyl Suppliers

Americas 1 Australia 1 Belgium 2 Canada 3 China 481 Europe 3 France 1 Germany 7 India 71 Italy 1 Japan 6 Slovakia 1 South Korea 3 Switzerland 2 The Netherlands 1 United Kingdom 16 United States 38 Global 638
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
More
Less

View Lastest Price from 4'-Methyl-2-cyanobiphenyl manufacturers

Jinan Finer Chemical Co., Ltd
Product
4'-Methyl-2-cyanobiphenyl 114772-53-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200mt
Release date
2019-04-02
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
4'-Methyl-2-cyanobiphenyl 114772-53-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99.91%
Supply Ability
200000
Release date
2024-04-24
airuikechemical co., ltd.
Product
4′-methyl-2-cyanobiphenyl 114772-53-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08

114772-53-1, 4'-Methyl-2-cyanobiphenylRelated Search:

trans-Bifenthtin 2-Chloro-3-cyanopyridine Bifendate Kresoxim-methyl Pirimiphos-methyl 4-Phenyltoluene Thiophanate-methyl Tribenuron methyl Bifonazole METSULFURON METHYL 2,3,3',4,4',5-HEXACHLOROBIPHENYL Methyl salicylate 4-Bromomethyl-2-cyanobiphenyl Methyl acetate 4-(2-Cyanophenyl)benzyl alcohol Methyl 4'-(Hydroxymethyl)-[1,1'-Biphenyl]-2-Carboxylic Acid N-Methylbenzene-1,2-diamine

  • methyl diphenyl
  • 2-cyanogen radical-4'-methyl biphenyl
  • 2-[(4-methyl)pentyl]-benzonitrile
  • OTBN
  • 4'-Methyl-2-Cyano Diphenyl
  • AKOS BAR-1203
  • 4'-METHYLBIPHENYL-2-CARBONITRILE
  • 4'-METHYL-2-BIPHENYLCARBONITRILE
  • 4'-METHYL-2-CYANOBIPHENYL
  • 4'-METHYL[1,1'-BIPHENYL]-2-CARBONITRILE
  • 2-(4-TOLYL)-BENZONITRILE
  • 2-(4-METHYLPHENYL)BENZONITRILE
  • [2-(P-TOLYL)BENZONITRILE]
  • 2-cyano-4methylbiphenyl 4'-Methylbiphenyl-2-carbonitrile
  • 2-CYANO-4''-METHYLBIPHENYL (OTBN)
  • 4''-METHYL-2-CYANO-BIPHENYL (FOR LOSARTAN)
  • 2-CYANO-4''-METHYLBIPHENYL(SARTANBIPHENYL)
  • 2-tolylbenzonitrile
  • 2-CYANO-4''-METHYLBIPHENYL 99%MIN
  • 2-Cyano-4'-methylbiphenyl
  • Sartandiphenyl
  • 4-Cyanomethylbiphenyl
  • 2-hexylbenzonitrile
  • OTBN (O-Tolybenzenitrile)
  • Sartanbiphenyl
  • o-(p-Tolyl)benzonitrile
  • 4'-Methyl-2-cyanobiphenyl,98%
  • 2-(4-Methylphenyl)benzenecarbonitrile
  • 2MPPC
  • 4'-Methyl-2-cyanobipheny
  • 4'-Methyl-2-cyanobip
  • 4'-Methyl-2-cyanobiphenyl ( OTBN )
  • diethyl 3-(3-acetyl-6-nitro-9H-carbazol-9-yl)propylphosphonate
  • [1,1'-Biphenyl]-2-carbonitrile, 4'-Methyl-
  • 4'-Methyl-2-cyanobiphenyl SynonyMs 4'-Methylbiphenyl-2-carbonitrile
  • Telmisartan Impurity 15
  • 2-Cyano-4'-methylbiphenyl &gt
  • 2-methyl-2-cyanobiphenyl
  • -2-cyanobiphenyL
  • OTBN 4’-Methyl-2-Cyano-Biphenyl
  • 4'-Methyl-2-cyanobiphenyl ISO 9001：2015 REACH
  • Ortho Tolyl Benzonitrile (OTBN)
  • 4'-methyl-[1,1'-biphenyl]-2-carbonitrile
  • 4'-Methyl-2-cyanobiphenyl
  • 114772-53-1
  • 14772-53-1
  • 114772-53-21
  • 114772-83-1
  • CH3C6H4C6H4CN
  • Biphenyl & Diphenyl ether
  • (intermediate of telmisartan)
  • (intermediate of sartan)
  • (intermediate of sartan s product)
  • Losartan Potassium
  • Biphenyl derivatives
  • INTERMEDIATESOF
  • Starting Raw Materials & Intermediates
  • cyanide