4'-Methyl-2-cyanobiphenyl
- Product Name
- 4'-Methyl-2-cyanobiphenyl
- CAS No.
- 114772-53-1
- Chemical Name
- 4'-Methyl-2-cyanobiphenyl
- Synonyms
- OTBN;2-Cyano-4'-methylbiphenyl;2MPPC;AKOS BAR-1203;Sartandiphenyl;Sartanbiphenyl;methyl diphenyl;-2-cyanobiphenyL;2-tolylbenzonitrile;2-hexylbenzonitrile
- CBNumber
- CB7337004
- Molecular Formula
- C14H11N
- Formula Weight
- 193.24
- MOL File
- 114772-53-1.mol
4'-Methyl-2-cyanobiphenyl Property
- Melting point:
- 49 °C
- Boiling point:
- >320°C
- Density
- 1,17 g/cm3
- vapor pressure
- 0.014Pa at 20℃
- Flash point:
- >320°C
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Crystalline Powder
- color
- Off-white to beige
- BRN
- 3605954
- InChI
- InChI=1S/C14H11N/c1-11-6-8-12(9-7-11)14-5-3-2-4-13(14)10-15/h2-9H,1H3
- InChIKey
- ZGQVZLSNEBEHFN-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=C(C)C=C2)=CC=CC=C1C#N
- LogP
- 3.5 at 23℃
- CAS DataBase Reference
- 114772-53-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzonitrile, 2-(4-methylphenyl)-(114772-53-1)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20/21/22-36/37/38-48/25/62/51/53-22
- Safety Statements
- 22-26-36/37/39-36/37/45/57-20-36
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 27075000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H313May be harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H401Toxic to aquatic life
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C1446
- Product name
- 2-Cyano-4'-methylbiphenyl
- Purity
- >99.0%(GC)
- Packaging
- 10g
- Price
- $37
- Updated
- 2024/03/01
- Product number
- B21273
- Product name
- 2-Cyano-4'-methylbiphenyl, 98+%
- Packaging
- 5g
- Price
- $50.8
- Updated
- 2024/03/01
- Product number
- B21273
- Product name
- 2-Cyano-4'-methylbiphenyl, 98+%
- Packaging
- 25g
- Price
- $162
- Updated
- 2024/03/01
- Product number
- B21273
- Product name
- 2-Cyano-4'-methylbiphenyl, 98+%
- Packaging
- 100g
- Price
- $431
- Updated
- 2024/03/01
- Product number
- M294115
- Product name
- 4''-Methylbiphenyl-2-carbonitrile
- Packaging
- 25g
- Price
- $185
- Updated
- 2021/12/16
4'-Methyl-2-cyanobiphenyl Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.
Synthesis
4'-Methyl-2-cyanobiphenyl is prepared by the reaction of o-cyanobromobenzene and potassium (4-methylphenyl)trifluoroborate. The specific synthesis steps are as follows:
General procedure: A mixture of aryl halide (0.5 mmol), potassium aryltrifluoroborate (0.6 mmol), K2CO3 (1.0 mmol), Pd/C (5%; 0.5 mol%), ethanol (3 mL), and distilled water (1 mL) was stirred at 80 °C in air for the time indicated.
The reaction mixture was added to brine (15 mL) and extracted with ethyl acetate (4×15 mL).
The organic solvent was removed under vacuum, and the product was isolated by short-column chromatography.
4'-Methyl-2-cyanobiphenyl Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4'-Methyl-2-cyanobiphenyl manufacturers
- Product
- 4'-Methyl-2-cyanobiphenyl 114772-53-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200mt
- Release date
- 2019-04-02
- Product
- 4'-Methyl-2-cyanobiphenyl 114772-53-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-01
- Product
- 4'-Methyl-2-cyanobiphenyl 114772-53-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-30