ChemicalBook > CAS DataBase List > 2-PIPERAZIN-1-YL-BENZALDEHYDE

2-PIPERAZIN-1-YL-BENZALDEHYDE

Product Name
2-PIPERAZIN-1-YL-BENZALDEHYDE
CAS No.
736991-52-9
Chemical Name
2-PIPERAZIN-1-YL-BENZALDEHYDE
Synonyms
1-(2-Formylphenyl)piperazine;2-(1-piperazinyl)benzaldehyde;2-PIPERAZIN-1-YL-BENZALDEHYDE;Benzaldehyde, 2-(1-piperazinyl)-;Benzaldehyde, 2-(1-piperazinyl)- (9CI)
CBNumber
CB7346631
Molecular Formula
C11H14N2O
Formula Weight
190.24
MOL File
736991-52-9.mol
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2-PIPERAZIN-1-YL-BENZALDEHYDE Property

Boiling point:
355.0±27.0 °C(Predicted)
Density 
1.123±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
8.86±0.10(Predicted)
CAS DataBase Reference
736991-52-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
Hazard Note 
Irritant
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P475288
Product name
2-(Piperazin-1-yl)benzaldehyde
Packaging
100mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR1644
Product name
2-(Piperazin-1-yl)benzaldehyde
Packaging
100mg
Price
$37
Updated
2021/12/16
SynQuest Laboratories
Product number
4H15-1-H0
Product name
2-Piperazin-1-ylbenzaldehyde
Packaging
250mg
Price
$40
Updated
2021/12/16
SynQuest Laboratories
Product number
4H15-1-H0
Product name
2-Piperazin-1-ylbenzaldehyde
Packaging
1g
Price
$47
Updated
2021/12/16
AK Scientific
Product number
W8175
Product name
2-Piperazin-1-yl-benzaldehyde
Packaging
1g
Price
$91
Updated
2021/12/16
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2-PIPERAZIN-1-YL-BENZALDEHYDE Chemical Properties,Usage,Production

Synthesis

110-85-0

446-52-6

736991-52-9

General procedure for the synthesis of 2-piperazine-1-benzaldehyde from piperazine and 2-fluorobenzaldehyde: 2-fluorobenzaldehyde (1.0 g, 8.1 mmol) was dissolved in N,N-dimethylformamide (15 ml) in a 50 ml round bottom flask. Piperazine (836 mg, 9.7 mmol) and potassium carbonate (1.68 g, 12.2 mmol) were then added and the reaction was carried out at 130 °C for 6 hours. After completion of the reaction, it was cooled to room temperature, the reaction mixture was diluted with water and extracted with ethyl acetate. The organic phases were combined and dried over anhydrous sodium sulfate. Purification was carried out by silica gel column chromatography (petroleum ether: ethyl acetate = 5:1; dichloromethane: methanol = 10:1), and the target compound 2-piperazine-1-benzaldehyde (760 mg, 49.4% yield) was obtained after concentration.

References

[1] Patent: CN105777632, 2016, A. Location in patent: Paragraph 0481; 0482; 0483

2-PIPERAZIN-1-YL-BENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-PIPERAZIN-1-YL-BENZALDEHYDE Suppliers

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