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Hydroxybupropione

Product Name
Hydroxybupropione
CAS No.
92264-81-8
Chemical Name
Hydroxybupropione
Synonyms
HYDROXYBUPROPION;HYDROXYBUPROPIONE;Bupropion Impurity 7;Bupropion Impurity 24;Hydroxymethyl Bupropion;(±)-Hydroxybupropion solution;Hydroxybupropione/Bupropion morpholinol;2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE;1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino;1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone
CBNumber
CB7367225
Molecular Formula
C13H18ClNO2
Formula Weight
255.74
MOL File
92264-81-8.mol
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Hydroxybupropione Property

Melting point:
121-123°C
Boiling point:
393.9±32.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
Flash point:
2℃
storage temp. 
-20°C
solubility 
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly)
form 
Solid
pka
15.43±0.10(Predicted)
color 
White to Pale Yellow
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Safety

Hazard Codes 
F,Xn
Risk Statements 
11-20/21/22-36
Safety Statements 
16-36/37
RIDADR 
UN 1648 3 / PGII
WGK Germany 
2
HS Code 
3822900000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P235Store in a well-ventilated place. Keep cool.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H-066
Product name
(±)-Hydroxybupropion solution
Purity
1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$57.1
Updated
2024/03/01
Usbiological
Product number
H9038-15
Product name
Hydroxybupropion
Packaging
10mg
Price
$439
Updated
2021/12/16
ChemScene
Product number
CS-0019871
Product name
Hydroxybupropion
Purity
99.91%
Packaging
5mg
Price
$250
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
MTB0000752
Product name
HYDROXYBUPROPIONE
Purity
95.00%
Packaging
5MG
Price
$497.02
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
33224
Product name
Hydroxybupropion
Purity
min.95%
Packaging
50mg
Price
$990
Updated
2021/12/16
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Hydroxybupropione Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

A metabolite of Bupropion, an antidepressant. The compound exists mainly as cyclic acetal (2-hydroxy-2-(3?chlorophenyl)-355-trimethylmorpholine). See US Pat. # 6342496

Definition

ChEBI: Hydroxybupropion is an aromatic ketone.

General Description

(±)-Hydroxybupropion is a primary metabolite of bupropion. Bupropion is a pharmaceutical used as an antidepressant and a smoking cessation drug sold under the trade names Wellbutrin? and Zyban?. This Certified Spiking Solution? is suitable for use in LC/MS or GC/MS applications for clinical toxicology, forensic analysis, urine drug testing, or pharmaceutical research.

Hydroxybupropione Preparation Products And Raw materials

Raw materials

Preparation Products

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Hydroxybupropione Suppliers

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92264-81-8, HydroxybupropioneRelated Search:

DIMETHYLAMINOPYRIDINE, POLYMER-BOUND Chlorodimethylphenylsilane Glycolic acid Hydroxy silicone oil HYDROXYAPATITE TYPE I 3,4'-DIAMINODIPHENYLMETHANE N,N-Dimethyl-1,4-phenylenediamine Betaine ALTRENOGEST 4-Hydroxybenzoic acid Silicone oil (high temperature) CHLOROPHOSPHONAZO III Bupropion Glycine Bupropion hydrochloride Camptothecin Series--10-hydroxycamptothecin TRIS EDTA ACETATE BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY Bupropion

  • HYDROXYBUPROPION
  • HYDROXYBUPROPIONE
  • 1-(3-CHLOROOPHENYL)-2-[(2-HYDROXY-1,1-DIMETHYLETHYL)AMINO]-1-PROPANONE
  • 2-HYDROXY-2-(3'-CHLOROPHENYL)-3,5,5-TRIMETHYLMORPHOLINE
  • 1-(3-Chloroophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone, 2-Hydroxy-2-(3chlorophenyl)-3,5,5-trimethylmorpholine
  • 1-(3-Chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino]propan-1-one
  • 1-(3-Chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-1-propanone
  • (±)-Hydroxybupropion solution
  • Bupropion Impurity 7
  • Bupropion Impurity 24
  • 1-Propanone, 1-(3-chlorophenyl)-2-[(2-hydroxy-1,1-dimethylethyl)amino]-
  • 1-(3-chlorophenyl)-2-[(1-hydroxy-2-methylpropan-2-yl)amino
  • Hydroxymethyl Bupropion
  • Hydroxybupropione/Bupropion morpholinol
  • 92264-81-8
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Bupropion