SB 218795

Product Name: SB 218795
CAS No.: 174635-53-1
Chemical Name: SB 218795
Synonyms: SB 218795;Sb 218795r;Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate;methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate;(-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide;(-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE;(R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID;Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-;Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-;constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3
CBNumber: CB7376630
Molecular Formula: C25H20N2O3
Formula Weight: 396.44
MOL File: 174635-53-1.mol

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SB 218795 Property

Boiling point:: 623.7±55.0 °C(Predicted)
Density: 1.237±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: 40 mg/mL, soluble
form: solid
pka: 11.41±0.46(Predicted)
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1376
Product name: SB218795
Purity: ≥99%(HPLC)
Packaging: 10
Price: $174
Updated: 2021/12/16

Tocris

Product number: 1376
Product name: SB218795
Purity: ≥99%(HPLC)
Packaging: 50
Price: $713
Updated: 2021/12/16

TRC

Product number: S155070
Product name: SB218795
Packaging: 50mg
Price: $865
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007579
Product name: SB 218795
Purity: 95.00%
Packaging: 50MG
Price: $1327.97
Updated: 2021/12/16

ApexBio Technology

Product number: B6710
Product name: SB218795
Packaging: 50mg
Price: $1362
Updated: 2021/12/16

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SB 218795 Chemical Properties,Usage,Production

Uses

SB 218795 is an NK3 receptor antagonist.

Definition

ChEBI: (2R)-2-[[oxo-(2-phenyl-4-quinolinyl)methyl]amino]-2-phenylacetic acid methyl ester is a member of quinolines.

Biological Activity

Potent, selective and competitive non-peptide NK 3 receptor antagonist (K i = 13 nM at hNK 3 ). Displays 90-fold and 7000-fold selectivity over hNK 2 and hNK 1 receptors respectively. Active in vivo , inhibiting agonist-induced pupillary constriction.

SB 218795 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 218795 Suppliers

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174635-53-1, SB 218795Related Search:

CHEMBRDG-BB 9071014 SB 218795 N-(2-HYDROXYETHYL)ISONICOTINAMIDE, 99 FOR-D-PHG-OH N-METHYL-1-QUINOLIN-4-YLMETHANAMINE N-ME-D-PHG-OH 2-methylquinoline-4-carboxamide D(-)-AC-ALPHA-PHENYLGLYCINOL

SB 218795

(-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE

(R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID

(-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide

Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-

Sb 218795r

methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate

constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3

Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-

Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate

174635-53-1