ChemicalBook > CAS DataBase List > SB 218795

SB 218795

Product Name
SB 218795
CAS No.
174635-53-1
Chemical Name
SB 218795
Synonyms
SB 218795;Sb 218795r;Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate;methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate;(-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide;(-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE;(R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID;Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-;Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-;constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3
CBNumber
CB7376630
Molecular Formula
C25H20N2O3
Formula Weight
396.44
MOL File
174635-53-1.mol
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SB 218795 Property

Boiling point:
623.7±55.0 °C(Predicted)
Density 
1.237±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 40 mg/mL, soluble
form 
solid
pka
11.41±0.46(Predicted)
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1376
Product name
SB218795
Purity
≥99%(HPLC)
Packaging
10
Price
$174
Updated
2021/12/16
Tocris
Product number
1376
Product name
SB218795
Purity
≥99%(HPLC)
Packaging
50
Price
$713
Updated
2021/12/16
TRC
Product number
S155070
Product name
SB218795
Packaging
50mg
Price
$865
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007579
Product name
SB 218795
Purity
95.00%
Packaging
50MG
Price
$1327.97
Updated
2021/12/16
ApexBio Technology
Product number
B6710
Product name
SB218795
Packaging
50mg
Price
$1362
Updated
2021/12/16
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SB 218795 Chemical Properties,Usage,Production

Uses

SB 218795 is an NK3 receptor antagonist.

Definition

ChEBI: (2R)-2-[[oxo-(2-phenyl-4-quinolinyl)methyl]amino]-2-phenylacetic acid methyl ester is a member of quinolines.

Biological Activity

Potent, selective and competitive non-peptide NK 3 receptor antagonist (K i = 13 nM at hNK 3 ). Displays 90-fold and 7000-fold selectivity over hNK 2 and hNK 1 receptors respectively. Active in vivo , inhibiting agonist-induced pupillary constriction.

SB 218795 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB 218795 Suppliers

China 25 Germany 1 Switzerland 1 United Kingdom 1 United States 5 Global 33
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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86-21-50328109
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3bsc@sina.com
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China
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Shanghai T&W Pharmaceutical Co., Ltd.
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+86 21 61551611
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+86 21 50676805
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China
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Tianjin Kailiqi Biotechnology Co., Ltd.
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15076683720
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022-23754520
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klq@cw-bio.com
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Shanghai Chaolan Chemical Technology Center
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QQ:65489617 15618227136
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21-5161 9052
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info@SuperLan-chem.com
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China
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15971444841
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amber@biochempartner.com
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Shanghai Dongyang Biotechnology Co., Ltd.
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chemsharker@126.com
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China
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15869524721
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3525679403@qq.com
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China
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Shanghai Universal Biotech Co.,Ltd
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18768175414
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gaojun@univ-bio.com
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China
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Bide Pharmatech Ltd.
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400-1647117 15221909166
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product02@bidepharm.com
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Aikon International Limited
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18626450290
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yftan@aikonchem.com
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China
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Nanjing Tengyi Biotechnology Co., Ltd
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025-58851786 17714337195
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sales@tybiochem.com
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China
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https://hanhongsci.com/
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021-54306202 18917919676
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Nanjing Shizhou Biology Technology Co.,Ltd
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025-85560043 15850508050
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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Wuhan Topule Biopharmaceutical Co., Ltd
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+8618327326525
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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+86-057181025280; +8617767106207
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sales@molcore.com
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Xiamen Huijia Biological Technology Co., Ltd.
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Beijing Bolide Biotechnology Co., Ltd.
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174635-53-1, SB 218795Related Search:

CHEMBRDG-BB 9071014 SB 218795 N-(2-HYDROXYETHYL)ISONICOTINAMIDE, 99 FOR-D-PHG-OH N-METHYL-1-QUINOLIN-4-YLMETHANAMINE N-ME-D-PHG-OH 2-methylquinoline-4-carboxamide D(-)-AC-ALPHA-PHENYLGLYCINOL

  • SB 218795
  • (-)-(R)-N-(ALPHA-METHOXYCARBONYLBENZYL)-2-PHENYLQUINOLINE-4-CARBOXAMIDE
  • (R)-[[(2-PHENYL-4-QUINOLINYL)CARBONYL]AMINO]-METHYL ESTER BENZENEACETIC ACID
  • (-)-(R)-N-(α-Methoxycarbonylbenzyl)-2-phenylquinoline-4-carboxamide
  • Benzeneacetic acid, alpha-(((2-phenyl-4-quinolinyl)carbonyl)amino)-, methyl ester, (alphar)-
  • Sb 218795r
  • methyl (2R)-2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate
  • constriction,SB-218795,Neurokinin Receptor,Inhibitor,neurokinin-3,NK receptor,pupillary,inhibit,Tachykinin receptor,SB218795,SB 218795,NK-3
  • Benzeneacetic acid, α-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-, methyl ester, (αR)-
  • Methyl (R)-2-phenyl-2-(2-phenylquinoline-4-carboxamido)acetate
  • 174635-53-1