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CDC

Product Name
CDC
CAS No.
132465-11-3
Chemical Name
CDC
Synonyms
CDC;Cdkn;CDC 5-LO inhibitor;CDC lipoxygenase inhibitor;-3,4-dihydroxy-α-cyanocinnamate;Cinnamyl-3,4-dihydroxy-α-cyanocinnamate;CINNAMYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMATE;Cinnamyl-3,4-dihydroxy-α-cyanocinnamate(CDC);Cinnamyl 3,4-dihydroxy-alpha-cyanocinnamate CDC;1-Cyclohexy1-3-(3-dimethylamino proply)carbodilimide methiodide
CBNumber
CB7380752
Molecular Formula
C19H15NO4
Formula Weight
321.33
MOL File
132465-11-3.mol
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CDC Property

Boiling point:
583.9±50.0 °C(Predicted)
Density 
1.326±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: ≥15mg/mL
pka
8.75±0.10(Predicted)
form 
powder
color 
light yellow to yellow
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Safety

Hazard Codes 
Xi,N
Risk Statements 
43-50/53
Safety Statements 
36/37-60-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
HazardClass 
9
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0105
Product name
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
Purity
≥98% (HPLC)
Packaging
5mg
Price
$133
Updated
2025/07/31
Sigma-Aldrich
Product number
SML0105
Product name
Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
Purity
≥98% (HPLC)
Packaging
25mg
Price
$584
Updated
2023/01/07
TRC
Product number
C263153
Product name
CDC
Packaging
25mg
Price
$125
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000085
Product name
CDC
Purity
95.00%
Packaging
10MG
Price
$205.8
Updated
2021/12/16
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CDC Chemical Properties,Usage,Production

Uses

CDC is an inhibitor of 5-LO, 12-LO, and 15-LO.

Biological Activity

Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC) is a potent and direct inhibitor of 5-LO (5-Lipoxygenase) th at reduces 5-LO activity in cell-free assays. CDC also inhibits 12-LO and 15-LO

in vivo

The high glucose and 12(S)-hydroxyeicosatetraenoic acid (HETE) could alter vascular endothelial (VE)-cadherin and β‐catenin phosphorylation levels, but did not alter total protein expression. However, the 12/15-LO inhibitor, Cinnamyl-3,4-dihydroxy-α-cyanocinnamate (CDC), antagonized the effect of high glucose on protein phosphorylation to mitigate destruction of the endothelial cell barrier, and the mouse diabetes mellitus model further confirmed these conclusions[1].

CDC Preparation Products And Raw materials

Raw materials

Preparation Products

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CDC Suppliers

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View Lastest Price from CDC manufacturers

.GZ HONESTCHEM CO.,LTD
Product
cdc
Price
US $3500.00/KG
Min. Order
1KG
Purity
99.8%
Supply Ability
500KG
Release date
2018-08-29
.GZ HONESTCHEM CO.,LTD
Product
CDC
Price
US $1.00/KG
Min. Order
1G
Purity
99.9%
Supply Ability
500KG
Release date
2018-09-02
Career Henan Chemical Co
Product
CDC 132465-11-3
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25

132465-11-3, CDCRelated Search:


  • CINNAMYL-3,4-DIHYDROXY-ALPHA-CYANOCINNAMATE
  • CDC
  • (E,Z)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid 3-phenyl-2-propenyl ester
  • Cinnamyl 3,4-dihydroxy-alpha-cyanocinnamate CDC
  • 1-Cyclohexy1-3-(3-dimethylamino proply)carbodilimide methiodide
  • -3,4-dihydroxy-α-cyanocinnamate
  • 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxyphenyl)-, 3-phenyl-2-propen-1-yl ester, (2E)-
  • Cinnamyl-3,4-dihydroxy-α-cyanocinnamate
  • CDC 5-LO inhibitor
  • CDC lipoxygenase inhibitor
  • Cinnamyl-3,4-dihydroxy-α-cyanocinnamate(CDC)
  • Cdkn
  • 132465-11-3
  • C19H15NO4