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SCOULERIN

Product Name
SCOULERIN
CAS No.
6451-73-6
Chemical Name
SCOULERIN
Synonyms
SCOULERIN;Scoreline;l-skoulerine;l-scoulerine;SCOULERIN(SH);Alkaloid HF-1;SCOULERIN(RG);(-)-scoulerine;(-)-Scoulerine;2,9-DIOXY-3,10-DIMETHOXYBERBINE
CBNumber
CB7382903
Molecular Formula
C19H21NO4
Formula Weight
327.37
MOL File
6451-73-6.mol
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SCOULERIN Property

Melting point:
192°C
Boiling point:
503.3±50.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
A crystalline solid
pka
9.88±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
S200805
Product name
S-(+)-Scoulerine
Packaging
10mg
Price
$3795
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS27806
Product name
S-Scoulerine
Packaging
5mg
Price
$197.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS27806
Product name
S-Scoulerine
Packaging
10mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0016658
Product name
Scoulerine
Packaging
5mg
Price
$480
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS27806
Product name
S-Scoulerine
Packaging
25mg
Price
$500
Updated
2021/12/16
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SCOULERIN Chemical Properties,Usage,Production

Description

This form of the alkaloid is more widespread than the d-form, occurring in Corydalis caseana, C. micrantha, C. montana, C. scouleri, C. sibirica and Papaver somniferum. It has [α]26D - 318° (c 0.41, MeOH) or - 289° (c 0.62, MeOH). It forms pale grey needles when crystallized from MeOH. The hydrochloride has m.p. 268-9°C; the picrate, m.p. 206°C (dec.) and the diethyl ether, m.p. 155°C. The oxidation products are the same as for the preceding base.

Chemical Properties

Off-White to Pale Pink Solid

Uses

The S-(+)-enantiomer of Scoulerine, an alkaloid found in the opium poppy.

Uses

(S)-Scoulerine is an alkaloid found in the opium poppy. (S)-Scoulerine acts as an antagonist at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor.

Definition

ChEBI: A berberine alkaloid isolated from Corydalis saxicola.

References

Manske., Can. J. Res., 14B, 347, 354 (1936)
Manske., ibid, 17B, 57 (1939)
Manske., ibid, 18B, 414 (1940)
Manske., ibid, 20B, 49 (1942)
Brochmann-Hanssen, Nielsen., Tetrahedron Lett., 2261 (1966)
Synthesis:
Kametani., Japanese Patent, 70, 37,976, 10 December 1970

SCOULERIN Preparation Products And Raw materials

Raw materials

Preparation Products

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SCOULERIN Suppliers

Canada 1 China 76 Germany 2 India 1 United Kingdom 3 United States 7 Global 90
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
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60
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
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55
Hunan Cangood Medical Technology Ltd.
Tel
400-026-9899
Fax
+86-731-86905278
Country
China
ProdList
71
Advantage
50
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
7059
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
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View Lastest Price from SCOULERIN manufacturers

Career Henan Chemical Co
Product
SCOULERIN 6451-73-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-03

6451-73-6, SCOULERINRelated Search:

VERATRINE veratramine VERATRIDINE L-Hyoscyamine Daurinoline menisdaurin Coptisine chloride Corydaline (-)-STYLOPINE SCOULERIN rotundine 13aalpha-Berbin-1-ol, 2,3,9,10-tetramethoxy- (8CI) AKOS 236-26 CYCLANOLINE CHLORIDE L-Tetrahydropalmatine hydrochloride AKOS 213-61 SCOULERIN(REAGENT / STANDARD GRADE) SCOULERIN HYDROCHLORIDE

  • SCOULERIN
  • SCOULERIN(SH)
  • (13aS)-5,8,13,13a-tTtrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol
  • (S)-5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-Dibenzo[a,g]quinolizine-2,9-diol
  • Alkaloid HF 1, froM HunneMannia fuMariaefolia
  • (-)-scoulerine
  • 3,10-dimethoxy-13a-alpha-berbine-2,9-diol
  • 3,10-dimethoxy-13a-alpha-berbine-9-diol
  • g)quinolizine-2,9-diol,5,8,13,13a-tetrahydro-3,10-dimethoxy-6h-dibenzo((
  • l-scoulerine
  • l-skoulerine
  • 2,9-DIOXY-3,10-DIMETHOXYBERBINE
  • (13aR)-5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol
  • [13aR,(+)]-5,8,13,13aβ-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol
  • 3,10-Dimethoxy-13aα-berbine-2,9-diol
  • Alkaloid HF-1
  • SCOULERIN(RG)
  • 6H-Dibenzo[a,g]quinolizine-2,9-diol, 5,8,13,13a-tetrahydro-3,10-dimethoxy-, (13aS)-
  • Scoreline
  • (13aS)-3,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,9-diol
  • (S)-3,10-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline-2,9-diol
  • proliferation,Inhibitor,cancer,Beta-secretase,Scoulerine,Apoptosis,inhibit,microtubule,cycle,β-Secretase,Microtubule/Tubulin,leukemic,BACE,cells,division,mitotic,Discretamine
  • (-)-Scoulerine
  • 6451-73-6
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Alkaloids