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SCOULERIN

Product Name
SCOULERIN
CAS No.
6451-73-6
Chemical Name
SCOULERIN
Synonyms
SCOULERIN;Scoreline;l-skoulerine;l-scoulerine;SCOULERIN(SH);Alkaloid HF-1;SCOULERIN(RG);(-)-scoulerine;(-)-Scoulerine;2,9-DIOXY-3,10-DIMETHOXYBERBINE
CBNumber
CB7382903
Molecular Formula
C19H21NO4
Formula Weight
327.37
MOL File
6451-73-6.mol
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SCOULERIN Property

Melting point:
192°C
Boiling point:
503.3±50.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
A crystalline solid
pka
9.88±0.20(Predicted)
color 
Off-white to pink
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
S200805
Product name
S-(+)-Scoulerine
Packaging
10mg
Price
$3795
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS27806
Product name
S-Scoulerine
Packaging
5mg
Price
$197.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS27806
Product name
S-Scoulerine
Packaging
10mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0016658
Product name
Scoulerine
Packaging
5mg
Price
$480
Updated
2021/12/16
Biosynth Carbosynth
Product number
FS27806
Product name
S-Scoulerine
Packaging
25mg
Price
$500
Updated
2021/12/16
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SCOULERIN Chemical Properties,Usage,Production

Description

This form of the alkaloid is more widespread than the d-form, occurring in Corydalis caseana, C. micrantha, C. montana, C. scouleri, C. sibirica and Papaver somniferum. It has [α]26D - 318° (c 0.41, MeOH) or - 289° (c 0.62, MeOH). It forms pale grey needles when crystallized from MeOH. The hydrochloride has m.p. 268-9°C; the picrate, m.p. 206°C (dec.) and the diethyl ether, m.p. 155°C. The oxidation products are the same as for the preceding base.

Chemical Properties

Off-White to Pale Pink Solid

Uses

The S-(+)-enantiomer of Scoulerine, an alkaloid found in the opium poppy.

Uses

(S)-Scoulerine is an alkaloid found in the opium poppy. (S)-Scoulerine acts as an antagonist at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor.

Definition

ChEBI: A berberine alkaloid isolated from Corydalis saxicola.

References

Manske., Can. J. Res., 14B, 347, 354 (1936)
Manske., ibid, 17B, 57 (1939)
Manske., ibid, 18B, 414 (1940)
Manske., ibid, 20B, 49 (1942)
Brochmann-Hanssen, Nielsen., Tetrahedron Lett., 2261 (1966)
Synthesis:
Kametani., Japanese Patent, 70, 37,976, 10 December 1970

SCOULERIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SCOULERIN manufacturers

Career Henan Chemical Co
Product
SCOULERIN 6451-73-6
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-03

6451-73-6, SCOULERINRelated Search:

VERATRINE veratramine VERATRIDINE L-Hyoscyamine Daurinoline menisdaurin Coptisine chloride Corydaline (-)-STYLOPINE SCOULERIN rotundine 13aalpha-Berbin-1-ol, 2,3,9,10-tetramethoxy- (8CI) AKOS 236-26 CYCLANOLINE CHLORIDE L-Tetrahydropalmatine hydrochloride AKOS 213-61 SCOULERIN(REAGENT / STANDARD GRADE) SCOULERIN HYDROCHLORIDE

  • SCOULERIN
  • SCOULERIN(SH)
  • (13aS)-5,8,13,13a-tTtrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol
  • (S)-5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-Dibenzo[a,g]quinolizine-2,9-diol
  • Alkaloid HF 1, froM HunneMannia fuMariaefolia
  • (-)-scoulerine
  • 3,10-dimethoxy-13a-alpha-berbine-2,9-diol
  • 3,10-dimethoxy-13a-alpha-berbine-9-diol
  • g)quinolizine-2,9-diol,5,8,13,13a-tetrahydro-3,10-dimethoxy-6h-dibenzo((
  • l-scoulerine
  • l-skoulerine
  • 2,9-DIOXY-3,10-DIMETHOXYBERBINE
  • (13aR)-5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol
  • [13aR,(+)]-5,8,13,13aβ-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol
  • 3,10-Dimethoxy-13aα-berbine-2,9-diol
  • Alkaloid HF-1
  • SCOULERIN(RG)
  • 6H-Dibenzo[a,g]quinolizine-2,9-diol, 5,8,13,13a-tetrahydro-3,10-dimethoxy-, (13aS)-
  • Scoreline
  • (13aS)-3,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,9-diol
  • (S)-3,10-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline-2,9-diol
  • proliferation,Inhibitor,cancer,Beta-secretase,Scoulerine,Apoptosis,inhibit,microtubule,cycle,β-Secretase,Microtubule/Tubulin,leukemic,BACE,cells,division,mitotic,Discretamine
  • (-)-Scoulerine
  • 6451-73-6
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Alkaloids