SCOULERIN

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Product Name: SCOULERIN
CAS No.: 6451-73-6
Chemical Name: SCOULERIN
Synonyms: SCOULERIN;Scoreline;l-skoulerine;l-scoulerine;SCOULERIN(SH);Alkaloid HF-1;SCOULERIN(RG);(-)-scoulerine;(-)-Scoulerine;2,9-DIOXY-3,10-DIMETHOXYBERBINE
CBNumber: CB7382903
Molecular Formula: C19H21NO4
Formula Weight: 327.37
MOL File: 6451-73-6.mol

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SCOULERIN Property

Melting point:: 192°C
Boiling point:: 503.3±50.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: A crystalline solid
pka: 9.88±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S200805
Product name: S-(+)-Scoulerine
Packaging: 10mg
Price: $3795
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FS27806
Product name: S-Scoulerine
Packaging: 5mg
Price: $197.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FS27806
Product name: S-Scoulerine
Packaging: 10mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0016658
Product name: Scoulerine
Packaging: 5mg
Price: $480
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FS27806
Product name: S-Scoulerine
Packaging: 25mg
Price: $500
Updated: 2021/12/16

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SCOULERIN Chemical Properties,Usage,Production

Description

This form of the alkaloid is more widespread than the d-form, occurring in Corydalis caseana, C. micrantha, C. montana, C. scouleri, C. sibirica and Papaver somniferum. It has [α]²⁶_D - 318° (c 0.41, MeOH) or - 289° (c 0.62, MeOH). It forms pale grey needles when crystallized from MeOH. The hydrochloride has m.p. 268-9°C; the picrate, m.p. 206°C (dec.) and the diethyl ether, m.p. 155°C. The oxidation products are the same as for the preceding base.

Chemical Properties

Off-White to Pale Pink Solid

Uses

The S-(+)-enantiomer of Scoulerine, an alkaloid found in the opium poppy.

Uses

(S)-Scoulerine is an alkaloid found in the opium poppy. (S)-Scoulerine acts as an antagonist at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor.

Definition

ChEBI: A berberine alkaloid isolated from Corydalis saxicola.

References

Manske., Can. J. Res., 14B, 347, 354 (1936)
Manske., ibid, 17B, 57 (1939)
Manske., ibid, 18B, 414 (1940)
Manske., ibid, 20B, 49 (1942)
Brochmann-Hanssen, Nielsen., Tetrahedron Lett., 2261 (1966)
Synthesis:
Kametani., Japanese Patent, 70, 37,976, 10 December 1970

SCOULERIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SCOULERIN manufacturers

Career Henan Chemical Co

Product: SCOULERIN 6451-73-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-03

6451-73-6, SCOULERINRelated Search:

VERATRINE veratramine VERATRIDINE L-Hyoscyamine Daurinoline menisdaurin Coptisine chloride Corydaline (-)-STYLOPINE SCOULERIN rotundine 13aalpha-Berbin-1-ol, 2,3,9,10-tetramethoxy- (8CI) AKOS 236-26 CYCLANOLINE CHLORIDE L-Tetrahydropalmatine hydrochloride AKOS 213-61 SCOULERIN(REAGENT / STANDARD GRADE) SCOULERIN HYDROCHLORIDE

SCOULERIN

SCOULERIN(SH)

(13aS)-5,8,13,13a-tTtrahydro-3,10-diMethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol

(S)-5,8,13,13a-Tetrahydro-3,10-diMethoxy-6H-Dibenzo[a,g]quinolizine-2,9-diol

Alkaloid HF 1, froM HunneMannia fuMariaefolia

(-)-scoulerine

3,10-dimethoxy-13a-alpha-berbine-2,9-diol

3,10-dimethoxy-13a-alpha-berbine-9-diol

g)quinolizine-2,9-diol,5,8,13,13a-tetrahydro-3,10-dimethoxy-6h-dibenzo((

l-scoulerine

l-skoulerine

2,9-DIOXY-3,10-DIMETHOXYBERBINE

(13aR)-5,8,13,13a-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol

[13aR,(+)]-5,8,13,13aβ-Tetrahydro-3,10-dimethoxy-6H-dibenzo[a,g]quinolizine-2,9-diol

3,10-Dimethoxy-13aα-berbine-2,9-diol

Alkaloid HF-1

SCOULERIN(RG)

6H-Dibenzo[a,g]quinolizine-2,9-diol, 5,8,13,13a-tetrahydro-3,10-dimethoxy-, (13aS)-

Scoreline

(13aS)-3,10-dimethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline-2,9-diol

(S)-3,10-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline-2,9-diol

proliferation,Inhibitor,cancer,Beta-secretase,Scoulerine,Apoptosis,inhibit,microtubule,cycle,β-Secretase,Microtubule/Tubulin,leukemic,BACE,cells,division,mitotic,Discretamine

(-)-Scoulerine

6451-73-6

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