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SB9200

Product Name
SB9200
CAS No.
942123-43-5
Chemical Name
SB9200
Synonyms
SB 44;SB9200;GS-9992);Irigivir soproxil;Inarigivir soproxil;SB9200;SB 9200;SB-9200;inarigivir soproxil SB9200;SB9200(Inarigivir soproxil);Inarigivir soproxil, 10 mM in DMSO;Inarigivir soproxil (Synonyms: SB9200
CBNumber
CB73959573
Molecular Formula
C25H34N7O13PS
Formula Weight
703.62
MOL File
942123-43-5.mol
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SB9200 Property

Density 
1.80±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 102 mg/mL (144.96 mM)
form 
Solid
pka
9.39±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
I627015
Product name
InarigivirSoproxil
Packaging
1mg
Price
$275
Updated
2021/12/16
ChemScene
Product number
CS-0030656
Product name
Inarigivirsoproxil
Purity
98.16%
Packaging
5mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0030656
Product name
Inarigivirsoproxil
Purity
98.16%
Packaging
10mg
Price
$850
Updated
2021/12/16
ChemScene
Product number
CS-0030656
Product name
Inarigivirsoproxil
Purity
98.16%
Packaging
25mg
Price
$1750
Updated
2021/12/16
ChemScene
Product number
CS-0030656
Product name
Inarigivirsoproxil
Purity
98.16%
Packaging
50mg
Price
$2750
Updated
2021/12/16
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SB9200 Chemical Properties,Usage,Production

Uses

Inarigivir soproxil, has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus (HBV) in vitro and in vivo.

in vivo

The induction of host immune responses by pretreatment with Inarigivir soproxil (SB 9200) followed by Entecavir (ETV) resulted in antiviral efficacy that was superior to that obtained using the strategy of viral reduction with ETV followed by immunomodulation[2].
Sequential treatment of chronic WHV carrier woodchucks with Inarigivir soproxil (30 mg/kg)followed by ETV induced marked suppression of serum viremia and antigenemia and delayed recrudescence of viral replication compared to sequential treatment with ETV followed by Inarigivir soproxil[2].

Animal Model:Woodchucks chronically infected with woodchuck hepatitis virus (WHV)[2]
Dosage:30 mg/kg
Administration:Orally treated once daily; group 1 received ETV for 4 weeks followed by Inarigivir soproxil for 12 weeks. Group 2 received Inarigivir soproxil for 12 weeks followed by ETV for 4 weeks
Result:Both groups demonstrated marked reductions in hepatic WHV nucleic acid levels which were more pronounced in Group 2.

SB9200 Preparation Products And Raw materials

Raw materials

Preparation Products

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SB9200 Suppliers

CHINA 43 United States 3 Global 46
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58

942123-43-5, SB9200Related Search:

Sb-742457 SBI-0206965 GSK-CXCR2 SBI-993 SB-649868 SB1317 SB 203580 SB 204741 SB1317

  • SB9200
  • Inarigivir soproxil
  • SB9200(Inarigivir soproxil)
  • SB9200;SB 9200;SB-9200
  • inarigivir soproxil SB9200
  • Irigivir soproxil
  • Adenosine, 2'-O-methyl-P(S)-[[[(1-methylethoxy)carbonyl]oxy]methyl]-P-thiouridylyl-(3'→5')-2'-deoxy-
  • GS-9992)
  • Inarigivir soproxil (Synonyms: SB9200
  • inhibit,Inhibitor,HCV replicon,GS-9992,SB-9200,GS9992,antiviral activity against,HCV,Hepatitis C virus,SB 9200,innate immunity,GS 9992,Inarigivir soproxil,HBV,Hepatitis B virus
  • (((((2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methoxy)(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-yl)oxy)phosphoryl)thio)methyl isopropyl carbonate
  • SB 44
  • 1-[(2R,3R,4R,5R)-4-[({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}[({[(propan-2-yloxy)carbonyl]oxy}methyl)sulfanyl]phosphoryl)oxy]-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • Inarigivir soproxil, 10 mM in DMSO
  • 942123-43-5
  • C25H34N7O13PS