ChemicalBook > CAS DataBase List > D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

Product Name
D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
CAS No.
103733-65-9
Chemical Name
D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Synonyms
D-TIC;H-D-TIC-OH;RARECHEM BK PT 0079;Icatibant Impurity 4;D-PHENYLALANINE ANALOGUE;D-1,2,3,4-Tetrahydroisoquinoline;Tetrahydroisoquinoline-3-carboxylic acid;D-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID;1,2,3,4-D-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID;1,2,3,4-TETRAHYDROISOQUINOLINE-(3R)-CARBOXYLIC ACID
CBNumber
CB7397017
Molecular Formula
C10H11NO2
Formula Weight
177.2
MOL File
103733-65-9.mol
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D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Property

Melting point:
320-323 °C (decomp)
Boiling point:
372.0±42.0 °C(Predicted)
Density 
1.225±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Slightly), Aqueous Base (Sparingly, Sonicated)
form 
Crystalline Powder
pka
2.21±0.20(Predicted)
color 
White
InChI
InChI=1S/C10H11NO2/c12-10(13)9-5-7-3-1-2-4-8(7)6-11-9/h1-4,9,11H,5-6H2,(H,12,13)/t9-/m1/s1
InChIKey
BWKMGYQJPOAASG-SECBINFHSA-N
SMILES
C1C2=C(C=CC=C2)C[C@H](C(O)=O)N1
CAS DataBase Reference
103733-65-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H29112
Product name
(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Packaging
1g
Price
$211.65
Updated
2024/03/01
Alfa Aesar
Product number
H29112
Product name
(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Packaging
5g
Price
$658.65
Updated
2024/03/01
Alfa Aesar
Product number
H29112
Product name
(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Packaging
250mg
Price
$86.65
Updated
2024/03/01
TRC
Product number
T294825
Product name
(R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
Packaging
250mg
Price
$50
Updated
2021/12/16
ApexBio Technology
Product number
C6784
Product name
(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylicacid
Packaging
100mg
Price
$60
Updated
2021/12/16
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D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Chemical Properties,Usage,Production

Description

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid ((3R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid) is a magnetic, neutral compound. It is used as a pharmacological study to investigate the reaction mechanism and kinetics of the deuteration process. The asymmetric synthesis of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has been investigated using vinylene chloride and hydantoin as reactants. There are various parameters that affect the kinetics of this reaction such as solvent type and temperature. The nitric oxide synthase inhibitor activity of D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid has been studied in vitro. Results have shown that it inhibits nitric oxide synthase by binding to the heme iron of the enzyme and preventing the conversion of arginine

Chemical Properties

White solid

Uses

(R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Definition

ChEBI: D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is a member of isoquinolines.

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid Suppliers

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View Lastest Price from D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
D-Tic-OH 103733-65-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%;99%
Supply Ability
1T+
Release date
2023-09-08
Sichuan Jiaying Lai Technology Co.,LTD
Product
D-TIC 103733-65-9
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-23
Career Henan Chemical Co
Product
D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid 103733-65-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-16

103733-65-9, D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acidRelated Search:

Tetrahydrofuran Isoquinoline cis-1,2,3,6-Tetrahydrophthalic anhydride 1,2,3,4-TETRAHYDROISOQUINOLINE 1,2,3,4-Tetrahydroquinoline Tetrahydrothiophene 1,2,3,4-Butanetetracarboxylic acid Isoquinoline-1-carboxylic acid Tetramethylammonium hydroxide pentahydrate Boc-D-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Boc-7-hydroxy-D-Tic-OH Boc-D-Tic(OH)-OH) FMOC-TIC-OH BOC-7-HYDROXY-TIC-OH Z-D-[3S]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID,Z-L-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID N-Fmoc-D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid FMOC-7-HYDROXY-(R)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (H-7-Hydroxy-Tic-OH) D-7-HYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID 2-benzyl-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid

  • 1,2,3,4-TETRAHYDROISOQUINOLINE-(3R)-CARBOXYLIC ACID
  • 1,2,3,4-D-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
  • 3-ISOQUINOLINECARBOXYLIC ACID, 1,2,3,4-TETRAHYDRO-, (3R)-
  • (3R)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
  • H-D-TIC-OH
  • D-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
  • D-[3R]-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
  • D-TIC
  • (R)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID
  • (R)-1,2,3,4-TETRAHYDRO-3-ISOQUINOLINECARBOXYLIC ACID
  • RARECHEM BK PT 0079
  • D-1,2,3,4-Tetrahydroisoquinoline
  • (R)-1,2,3,4-Tetrahydro-3-Isoquinoliceearboxylic Acid
  • Icatibant Impurity 4
  • D-PHENYLALANINE ANALOGUE
  • (3R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid
  • (R)-1,2,3,4-Tetrahydro-isoquinolin-3-carboxylic acid
  • H-D-Tic-OH D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
  • (3R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid≥ 99% (assay)
  • (R)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid,99%e.e.
  • Tetrahydroisoquinoline-3-carboxylic acid
  • (R)-(+)-1,2,3,4-Tetrahydroisoquinoline-3-CarboxylicAci
  • D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid USP/EP/BP
  • 103733-65-9 D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid
  • 103733-65-9
  • Others
  • Peptide Synthesis
  • Specialty Synthesis
  • Unnatural Amino Acid Derivatives
  • a-amino
  • Others
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Amino Acids