ChemicalBook > CAS DataBase List > 5-AMINO-1-ETHYLPYRAZOLE

5-AMINO-1-ETHYLPYRAZOLE

Product Name: 5-AMINO-1-ETHYLPYRAZOLE
CAS No.: 3528-58-3
Chemical Name: 5-AMINO-1-ETHYLPYRAZOLE
Synonyms: AKOS B024267;ART-CHEM-BB B024267;TIMTEC-BB SBB005554;5-Amino-1-ethylpyrazol;1-ethy-pyrazol-5-aMine;2-ethyl-3-pyrazolamine;2-ethylpyrazol-3-amine;2-Amino-1-ethylpyrazole;5-AMINO-1-ETHYLPYRAZOLE;2-Ethyl-3-aMinopyrazole
CBNumber: CB7401714
Molecular Formula: C5H9N3
Formula Weight: 111.15
MOL File: 3528-58-3.mol

Less

5-AMINO-1-ETHYLPYRAZOLE Property

Melting point:: 52-57 °C (lit.)
Boiling point:: 92-94 °C/0.01 mmHg (lit.)
Density: 1.0671 (rough estimate)
refractive index: 1.5340 (estimate)
Flash point:: >230 °F
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
pka: 4.18±0.10(Predicted)
Appearance: Off-white to light yellow Solid
CAS DataBase Reference: 3528-58-3(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 295760
Product name: 5-Amino-1-ethylpyrazole
Purity: 99%
Packaging: 1g
Price: $83
Updated: 2023/06/20

Sigma-Aldrich

Product number: 295760
Product name: 5-Amino-1-ethylpyrazole
Purity: 99%
Packaging: 5g
Price: $253
Updated: 2022/05/15

TCI Chemical

Product number: A3482
Product name: 1-Ethyl-1H-pyrazol-5-amine
Purity: min. 98.0 %
Packaging: 1G
Price: $89
Updated: 2025/07/31

TCI Chemical

Product number: A3482
Product name: 1-Ethyl-1H-pyrazol-5-amine
Purity: min. 98.0 %
Packaging: 5G
Price: $267
Updated: 2025/07/31

TRC

Product number: B124855
Product name: 1-Ethyl-1H-pyrazol-5-amine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Less

5-AMINO-1-ETHYLPYRAZOLE Chemical Properties,Usage,Production

Uses

5-Amino-1-ethylpyrazole is a heterocyclic building block, has been used in the preparation of 1-protected-1H-pyrazolo[3,4-b]pyridines.

Synthesis

75-07-0

107-13-1

3528-58-3

1. Hydrazine hydrate (98.7 g, 1.97 mol) was slowly added dropwise to a solution of 2-acrylonitrile (100 g, 1.88 mol) in tetrahydrofuran (350 ml) at 0-5 °C. 2. The reaction mixture was stirred at room temperature for 3 h. 3. Acetaldehyde (86.9 g, 1.9 mol) was slowly added dropwise to the above mixture, and stirring was continued for 3 h at room temperature. 4. The solvent was removed by distillation under reduced pressure to give a yellow oil. 5. The oil was dissolved in n-butanol (100 ml), followed by addition of a solution of n-butanol (250 ml) containing potassium tert-butanolate (221 g, 1.9 mol). 6. The reaction mixture was gradually heated from room temperature to 120 °C and maintained at this temperature for 3 h. 7. After completion of the reaction, the reaction was cooled to room temperature, and diluted with water (500 ml). 8. ) for dilution. 8. The reaction mixture was extracted with ethyl acetate (3 x 500 ml). 9. The organic layers were combined and dried over anhydrous sodium sulfate, followed by concentration in vacuo. 10. Purification was carried out by column chromatography using silica gel saturated with triethylamine (100-200 mesh), with 20% ethyl acetate in hexane as eluent. 11. The target fractions were collected to afford 1-ethyl-1H-pyrazol-5-amine, Yield: 66.0 g (1.0 g). 12. , Yield: 66.0 g (15% yield), mass spectrum (m/z): (M+H)+ 111.98.

References

[1] Patent: WO2010/46791, 2010, A1. Location in patent: Page/Page column 30-31

5-AMINO-1-ETHYLPYRAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-AMINO-1-ETHYLPYRAZOLE Suppliers

China 84 Germany 2 India 2 Russia 1 Switzerland 1 Ukraine 2 United Kingdom 7 United States 19 Global 118

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

ChemFuture PharmaTech (Jiangsu) Ltd

Tel: 5108538618
Fax: 86 510 85386988-8017
Email: suger.wang@chemfuture.com
Country: China
ProdList: 832
Advantage: 65

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9476
Advantage: 58

ShangHai KenEn Chemical Technology Co., Ltd.

Tel: 13120367189
Fax: 021-50315529
Email: mychess007@163.com
Country: China
ProdList: 1994
Advantage: 55

Changsha Luxing Bio-Chem Technology Co., Ltd.

Tel: 0731-88827538 15873153880
Fax: 0731-88827238
Email: luxingbc@126.com
Country: China
ProdList: 2002
Advantage: 65

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Bellen Chemistry Co., Ltd.

Tel: 010-60400365-8001 15910885229
Fax: 010-60400361
Email: service@bellenchem.com
Country: China
ProdList: 4514
Advantage: 60

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Shanghai Brain Biotechnology Co., Ltd.

Tel: 13564638271
Fax: 021-68948280
Email: shhjiang1977@163.com
Country: China
ProdList: 2987
Advantage: 55

Lanzhou Angeli Biochemical Technology Co., Ltd.

Tel: 0931-8235634 13321316780
Fax: +86(931) 4873122
Email: 1455540579@qq.com
Country: China
ProdList: 958
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Xiaojia Technology Co., Ltd.

Tel: 15902830537
Email: zhanghao@happysyn.com
Country: China
ProdList: 3180
Advantage: 55

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Bejing Famous Pharmaceutical Technology Co., Ltd.

Tel: 13331045123
Fax: 86-10-80339217
Email: 2559355526@qq.com
Country: China
ProdList: 14193
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Wenjia Biomedical Technology Co., Ltd.

Tel: 15001899038 15001899038;
Email: wenjiayiyao@126.com
Country: China
ProdList: 996
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

Blocksynth Pharmaceutical Technology Co.,Ltd

Tel: 0086-19817745290; +8619817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5661
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Chengdu Feibo Pharm Technology Co., Ltd

Tel: +86 028-84641798 15982321820
Email: abby@arkpharm.com
Country: China
ProdList: 10000
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Qi Qi hang Biotechnology Co., Ltd.

Tel: 18151111370
Email: 1046215251@qq.com
Country: China
ProdList: 5999
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-029-81138252 +86-173 9270 1263
Fax: 029-88380327
Email: 1057@dideu.com
Country: China
ProdList: 3999
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Ruipu Medical Technology Co., Ltd

Tel: 15895968936
Fax: qq 1018762393
Email: 1018762393@qq.com
Country: China
ProdList: 9999
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9681
Advantage: 58

JinOu Biomedical (Nanjing) Co., Ltd.

Tel: 13000000000
Fax: jinoupharma@163
Email: jinoupharma@163.com
Country: China
ProdList: 11721
Advantage: 58

R.R Scientific, LLC.

Tel: 15010167677
Email: zhiyuu1218@163.com
Country: China
ProdList: 876
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Hubei Hannuo Pharmaceutical Technology Co., Ltd

Tel: 18662190603
Email: 437347250@qq.com
Country: China
ProdList: 7325
Advantage: 58

Less

View Lastest Price from 5-AMINO-1-ETHYLPYRAZOLE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 5-Amino-1-ethylpyrazol 3528-58-3
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-19

Career Henan Chemical Co

Product: 5-AMINO-1-ETHYLPYRAZOLE 3528-58-3
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2019-12-25

3528-58-3, 5-AMINO-1-ETHYLPYRAZOLERelated Search:

4,7-DIMETHYLPYRAZOLO(1,5-A)PYRIMIDINE-3-CARBOXYLIC ACID 5-AMINO-4-CYANO-1-(2-HYDROXYETHYL)PYRAZOLE 4,7-DIMETHYLPYRAZOLO[5,1-C][1,2,4]TRIAZINE-3-CARBOXYLIC ACID 5-AMINO-1-ETHYLPYRAZOLE 3-Amino-4-ethylpyrazole 3-AMINO-4-ETHYLPYRAZOLE OXALATE 1-Ethylpyrazole ETHYL 7-METHYL-2-(2-THIENYL)PYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE ETHYL 2-METHYL-7-OXO-4,7-DIHYDROPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE 1-(4,7-DIMETHYLPYRAZOLO[5,1-C][1,2,4]TRIAZIN-3-YL)ETHAN-1-ONE 5,7-BIS(TRIFLUOROMETHYL)-3-CYANOPYRAZOLO[1,5-A]PYRIMIDINE 2,3-dihydro-1H-imidazo[1,2-b]pyrazole ETHYL 7-METHYL-2-PHENYLPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE ETHYL 2,7-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE 5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile ALLOPURINOL RIBOSIDE 1-[2-(4-CHLOROPHENYL)-7-METHYLPYRAZOLO[1,5-A]PYRIMIDIN-6-YL]ETHAN-1-ONE 1-(2,7-DIMETHYLPYRAZOLO[1,5-A]PYRIMIDIN-6-YL)ETHAN-1-ONE

TIMTEC-BB SBB005554

ART-CHEM-BB B024267

1-ETHYL-1H-PYRAZOL-5-AMINE

2-ETHYL-2H-PYRAZOL-3-YLAMINE

AKOS B024267

5-AMINO-1-ETHYLPYRAZOLE

2-Amino-1-ethylpyrazole

5-Amino-1-ethylpyrazol

5-Amino-1-ethyl-1H-pyrazole

2-Ethyl-3-aMinopyrazole

1H-Pyrazol-5-aMine, 1-ethyl-

1-ethy-pyrazol-5-aMine

1-Ethyl-5-aMinopyrazole

(2-ethylpyrazol-3-yl)amine

2-ethyl-3-pyrazolamine

2-ethylpyrazol-3-amine

1-Ethylpyrazol-5-ylamine

1-Ethyl-1H-pyrazol-5-ylamine

3528-58-3

Pyrazoles

AMINO

Building Blocks

Heterocyclic Building Blocks

Pyrazoles