3-Amino-4-ethylpyrazole
- Product Name
- 3-Amino-4-ethylpyrazole
- CAS No.
- 43024-15-3
- Chemical Name
- 3-Amino-4-ethylpyrazole
- Synonyms
- 3-Amino-4-ethylpyrazole;4-ethyl-1H-pyrazol-3-amine;3-Amino-4-ethyl-1H-pyrazole;1H-Pyrazol-3-amine, 4-ethyl-;4-ethyl-1(2)H-pyrazol-3-ylaMine
- CBNumber
- CB8947361
- Molecular Formula
- C5H9N3
- Formula Weight
- 111.15
- MOL File
- 43024-15-3.mol
3-Amino-4-ethylpyrazole Property
- Boiling point:
- 307.2±22.0 °C(Predicted)
- Density
- 1.156±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 16.12±0.50(Predicted)
- form
- Solid
- Water Solubility
- Slightly soluble in water.
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- E902285
- Product name
- 4-ethyl-1H-pyrazol-3-amine
- Packaging
- 500mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- 119571
- Product name
- 4-Ethyl-1H-pyrazol-3-amine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $378
- Updated
- 2021/12/16
- Product number
- 3H30-1-9U
- Product name
- 3-Amino-4-ethyl-1H-pyrazole
- Packaging
- 5G
- Price
- $551
- Updated
- 2021/12/16
- Product number
- 3H30-1-9U
- Product name
- 3-Amino-4-ethyl-1H-pyrazole
- Packaging
- 1g
- Price
- $212
- Updated
- 2021/12/16
- Product number
- Q798
- Product name
- 3-Amino-4-ethylpyrazole
- Packaging
- 1g
- Price
- $260
- Updated
- 2021/12/16
3-Amino-4-ethylpyrazole Chemical Properties,Usage,Production
Uses
3-Amino-4-ethyl-1H-pyrazole is employed as a intermediate for chemical research and pharmaceutical.
Synthesis
43024-14-2
43024-15-3
The general procedure for the synthesis of 4-ethyl-1H-pyrazol-3-amine from 2-formylbutanenitrile was as follows: potassium tert-butanolate (112.0 g, 1.00 mol) was placed in a 5 L flask fitted with a charging funnel under nitrogen protection, and anhydrous ether (3.0 L) was added and stirred to dissolve. Subsequently, a mixed solution of 2-formylbutanenitrile (69.0 g, 1.00 mol) with methyl acetate (77.7 g, 1.05 mol) was added slowly dropwise over a period of 3 hours. After the dropwise addition was completed, the reaction mixture was stirred at room temperature overnight. After the reaction was complete, the mixture was cooled to 0 °C, neutralized by the addition of acetic acid (57 mL), the reaction mixture was filtered and the solids were washed with ether (500 mL). The filtrates were combined and rotary evaporated at room temperature to give a light yellow oil (95.1 g). This oil was dissolved in anhydrous ethanol (100 mL), 99% hydrazine monohydrate (48 mL) and acetic acid (14 mL) were added sequentially and refluxed overnight under nitrogen protection. At the end of the reaction, the solvent was removed by evaporation and the resulting oil was purified by silica gel column chromatography, using a methanol solution of dichloromethane:7N ammonia as eluent. Finally 22.4 g (20% yield) of 3-amino-4-ethylpyrazole was obtained as a clear oily substance, which solidified on standing.
References
[1] Patent: US2005/187219, 2005, A1. Location in patent: Page/Page column 18
[2] Patent: US2006/281756, 2006, A1. Location in patent: Page/Page column 7
3-Amino-4-ethylpyrazole Preparation Products And Raw materials
Raw materials
Preparation Products
3-Amino-4-ethylpyrazole Suppliers
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 15883
- Advantage
- 64
- Tel
- 0731-85526065 13308475853
- ivy@hnhbsj.com
- Country
- China
- ProdList
- 7247
- Advantage
- 62
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4000
- Advantage
- 55
- Tel
- 021-62594801
- Fax
- 021-62145414
- shliangyi@liangyichem.com
- Country
- China
- ProdList
- 50
- Advantage
- 58
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- +86 (21) 5471-7132
- Fax
- +86 (21) 5471-6993
- Country
- China
- ProdList
- 344
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
View Lastest Price from 3-Amino-4-ethylpyrazole manufacturers
- Product
- 3-Amino-4-ethylpyrazole 43024-15-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2 MTs
- Release date
- 2024-08-06