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3-Aminopyrazole

Product Name
3-Aminopyrazole
CAS No.
1820-80-0
Chemical Name
3-Aminopyrazole
Synonyms
1H-PYRAZOL-3-AMINE;3-Bromo-2-chloropyridine-4-carboxylic acid;3(5)-Aminopyrazole;1H-PYRAZOL-3-YLAMINE;NSC 76122;INDIP-021;AKOS B007331;3-PYRAZOLAMINE;3-AMINOPYRAZOL;5-Pyrazolamine
CBNumber
CB2322586
Molecular Formula
C3H5N3
Formula Weight
83.09
MOL File
1820-80-0.mol
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3-Aminopyrazole Property

Melting point:
34-37 °C (lit.)
Boiling point:
218 °C/122 mmHg (lit.)
Density 
1.0248 (rough estimate)
refractive index 
1.5060 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
soluble in Methanol
pka
15.28±0.10(Predicted)
form 
Oily Liquid or Crystalline Low Melting Solid
color 
White to light yellow
Sensitive 
Air & Light Sensitive
BRN 
1618
InChIKey
JVVRJMXHNUAPHW-UHFFFAOYSA-N
CAS DataBase Reference
1820-80-0(CAS DataBase Reference)
NIST Chemistry Reference
3(5)-aminopyrazole(1820-80-0)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34-36/37/38
Safety Statements 
26-36/37/39-45-27
RIDADR 
UN 3263 8/PG 2
WGK Germany 
3
8-10-23
Hazard Note 
Corrosive
HazardClass 
IRRITANT
HazardClass 
8
PackingGroup 
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
160644
Product name
3-Aminopyrazole
Purity
98%
Packaging
2.5g
Price
$88.1
Updated
2024/03/01
Sigma-Aldrich
Product number
160644
Product name
3-Aminopyrazole
Purity
98%
Packaging
10g
Price
$171
Updated
2024/03/01
TCI Chemical
Product number
A1859
Product name
3-Aminopyrazole
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
A1859
Product name
3-Aminopyrazole
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$84
Updated
2024/03/01
Alfa Aesar
Product number
A14458
Product name
3-Amino-1H-pyrazole, 97+%
Packaging
1g
Price
$33.65
Updated
2024/03/01
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3-Aminopyrazole Chemical Properties,Usage,Production

Chemical Properties

3-Aminopyrazole is Low-Melting Yellow Solid

Uses

3-Aminopyrazole is used in the preparation of heterocyclic compounds of pharamaceutical interest

Uses

Employed in a one-pot synthesis of pyrazolopyrimidines.1

Uses

3-Aminopyrazole was used in the spectroscopic characterization of ferrocenoyl peptides via 1H-NMR spectroscopy. It was also used in the synthesis of:

  • symmetrical dialkylpyrazolo[1,5-a]pyrimidines via condensation with symmetrical β-diketones
  • 3,4-annelated coumarins
  • heterocyclic compounds of pharmaceutical interest
  • pyrazolopyrimidines

General Description

3-Aminopyrazole is a heteroarylamine.

Synthesis

The synthesis of 3-Aminopyrazole is as follows:A solution of 50 mg (0.34 mmol) of 3-oxo-3-phenylpropanenitrile and 11.6 mg (0.36 mmol) of hydrazine and 0.024 mL of acetic acid (0.37 mmol) in 3 mL of anhydrous ethanol was heated at 60° C for 24 hr. The mixture was cooled to ambient temperature and the solvent removed in vacuo. The residue was taken up in ethyl acetate, washed with saturated sodium bicarbonate. The organic layer was washed with brine and dried over MgSO4, filtered and evaporated. The solid residue waswashedwithethyl ether and dried in vacuo to give 45 mg (82%) of 3-phenyl-1H-pyrazol-5-amine.

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3-Aminopyrazole Suppliers

Weifang Weimeng Chemical Co., Ltd.
Tel
0536-8790166 15105445095
Email
weimengchem@163.com
Country
China
ProdList
459
Advantage
58
Nanjing Jubai Biomedical Technology Co., Ltd.
Tel
13585203734
Email
235694118@qq.com
Country
China
ProdList
280
Advantage
58
Shanghai Arbor Chemical Co., Ltd.
Tel
021-021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
922
Advantage
55
Shanghai Zhibang Biological Medicine Co., LTD
Tel
021-54285032 18116461626
Fax
021-54285032
Email
25493162@qq.com
Country
China
ProdList
133
Advantage
58
YANCHENG JIANGZHONG CHEMICALS CO., LTD.
Tel
0515-88981987 13365196093
Fax
0515-88981987
Email
richard.li_jzchem@263.net
Country
China
ProdList
305
Advantage
58
Ningbo jinuo chemical co., LTD
Tel
0574-87314919 057487319282
Email
info@nbinno.com
Country
China
ProdList
7216
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
133-96369453 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
852
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15820
Advantage
58
Nanjing Yihua Biotechnology Co., Ltd
Tel
15850730945; 15850730945
Email
1334103687@qq.com
Country
China
ProdList
286
Advantage
58
Shanghai Tuolei Chemical Reagents Co., Ltd.
Tel
86-021-50318510
Fax
021-58650104
Country
China
ProdList
69
Advantage
55
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View Lastest Price from 3-Aminopyrazole manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
3-Aminopyrazole 1820-80-0
Price
US $10.00/kg
Min. Order
1kg
Purity
99.6%
Supply Ability
100000
Release date
2024-04-25
Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
3-Aminopyrazole 1820-80-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99.91%
Supply Ability
200000
Release date
2024-04-19
Hebei Guanlang Biotechnology Co., Ltd.
Product
3-Aminopyrazole 1820-80-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2023-03-22

1820-80-0, 3-AminopyrazoleRelated Search:


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  • 1820-80-0
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  • C3H5N3
  • Pyrazoles
  • Building Blocks
  • C3 to C5
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Pyrazoles
  • Miscellaneous Reagents
  • Heterocyclic Compounds
  • Amines
  • Pyrazoles & Triazoles
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Pyrazoles & Triazoles
  • Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
  • bc0001