ChemicalBook > CAS DataBase List > 3-Aminopyrazole

3-Aminopyrazole

Product Name
3-Aminopyrazole
CAS No.
1820-80-0
Chemical Name
3-Aminopyrazole
Synonyms
1H-PYRAZOL-3-AMINE;3-Bromo-2-chloropyridine-4-carboxylic acid;3(5)-Aminopyrazole;1H-PYRAZOL-3-YLAMINE;NSC 76122;INDIP-021;AKOS B007331;3-PYRAZOLAMINE;3-AMINOPYRAZOL;5-Pyrazolamine
CBNumber
CB2322586
Molecular Formula
C3H5N3
Formula Weight
83.09
MOL File
1820-80-0.mol
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3-Aminopyrazole Property

Melting point:
34-37 °C (lit.)
Boiling point:
218 °C/122 mmHg (lit.)
Density 
1.0248 (rough estimate)
refractive index 
1.5060 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
soluble in Methanol
pka
15.28±0.10(Predicted)
form 
Oily Liquid or Crystalline Low Melting Solid
color 
White to light yellow
Sensitive 
Air & Light Sensitive
BRN 
1618
InChIKey
JVVRJMXHNUAPHW-UHFFFAOYSA-N
CAS DataBase Reference
1820-80-0(CAS DataBase Reference)
NIST Chemistry Reference
3(5)-aminopyrazole(1820-80-0)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34-36/37/38
Safety Statements 
26-36/37/39-45-27
RIDADR 
UN 3263 8/PG 2
WGK Germany 
3
F 
8-10-23
Hazard Note 
Corrosive
HazardClass 
IRRITANT
HazardClass 
8
PackingGroup 
Ⅱ
HS Code 
29331990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
160644
Product name
3-Aminopyrazole
Purity
98%
Packaging
2.5g
Price
$88.1
Updated
2024/03/01
Sigma-Aldrich
Product number
160644
Product name
3-Aminopyrazole
Purity
98%
Packaging
10g
Price
$171
Updated
2024/03/01
TCI Chemical
Product number
A1859
Product name
3-Aminopyrazole
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
A1859
Product name
3-Aminopyrazole
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$84
Updated
2024/03/01
Alfa Aesar
Product number
A14458
Product name
3-Amino-1H-pyrazole, 97+%
Packaging
1g
Price
$33.65
Updated
2024/03/01
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3-Aminopyrazole Chemical Properties,Usage,Production

Chemical Properties

3-Aminopyrazole is Low-Melting Yellow Solid

Uses

3-Aminopyrazole is used in the preparation of heterocyclic compounds of pharamaceutical interest

Uses

Employed in a one-pot synthesis of pyrazolopyrimidines.1

Uses

3-Aminopyrazole was used in the spectroscopic characterization of ferrocenoyl peptides via 1H-NMR spectroscopy. It was also used in the synthesis of:

  • symmetrical dialkylpyrazolo[1,5-a]pyrimidines via condensation with symmetrical β-diketones
  • 3,4-annelated coumarins
  • heterocyclic compounds of pharmaceutical interest
  • pyrazolopyrimidines

General Description

3-Aminopyrazole is a heteroarylamine.

Synthesis

The synthesis of 3-Aminopyrazole is as follows:A solution of 50 mg (0.34 mmol) of 3-oxo-3-phenylpropanenitrile and 11.6 mg (0.36 mmol) of hydrazine and 0.024 mL of acetic acid (0.37 mmol) in 3 mL of anhydrous ethanol was heated at 60° C for 24 hr. The mixture was cooled to ambient temperature and the solvent removed in vacuo. The residue was taken up in ethyl acetate, washed with saturated sodium bicarbonate. The organic layer was washed with brine and dried over MgSO4, filtered and evaporated. The solid residue waswashedwithethyl ether and dried in vacuo to give 45 mg (82%) of 3-phenyl-1H-pyrazol-5-amine.

3-Aminopyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

3-NITRO-1H-PYRAZOLO[3,4-B]PYRIDINE 1H-Pyrazolo[3,4-b]pyridin-3-amine 8-BROMO-4-CHLORO-2-METHYLTHIOPYRAZOLO[1,5-A]1,3,5-TRIAZINE 4-CHLORO-2-METHYLTHIOPYRAZOLO[1,5-A]1,3,5-TRIAZINE 1H-PYRAZOLO[3,4-B]PYRIDINE 1H-PYRAZOLO[3,4-B]PYRIDINE, 3-BROMO- 3-Amino-4-bromopyrazole
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3-Aminopyrazole Suppliers

Americas 1 Belgium 3 Canada 2 China 416 Europe 2 France 1 Germany 8 Hungary 1 India 37 Japan 5 Russia 1 Switzerland 4 The Netherlands 1 Ukraine 2 United Kingdom 23 United States 67 Global 574
BTC pharm India
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GLR Innovations
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View Lastest Price from 3-Aminopyrazole manufacturers

Hubei Lidu New Material Technology Co., Ltd
Product
3-Aminopyrazole 1820-80-0
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
20TON
Release date
2024-12-11
Hebei Mujin Biotechnology Co.,Ltd
Product
3-Aminopyrazole 1820-80-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-25
Hebei Weibang Biotechnology Co., Ltd
Product
3-Aminopyrazole 1820-80-0
Price
US $9.90/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-12-03

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  • 1820-80-0
  • 1820-80-8
  • C3H5N3
  • Pyrazoles
  • Building Blocks
  • C3 to C5
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Pyrazoles
  • Miscellaneous Reagents
  • Heterocyclic Compounds
  • Amines
  • Pyrazoles & Triazoles
  • Bases & Related Reagents
  • Heterocycles
  • Nucleotides
  • Pyrazoles & Triazoles
  • Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
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