5-AMINO-1-PHENYLPYRAZOLE

Product Name: 5-AMINO-1-PHENYLPYRAZOLE
CAS No.: 826-85-7
Chemical Name: 5-AMINO-1-PHENYLPYRAZOLE
Synonyms: BUTTPARK 23\09-46;Aminophenylpyrazole;2-phenylpyrazol-3-amine;5-AMINO-1-PHENYLPYRAZOLE;5-amino-1-phenyl-pyrazol;1-phenylpyrazol-5-ylamine;1-phenyl-1h-pyrazol-5-amin;1-Phenyl-1H-pyrazol-5-amine;(2-phenylpyrazol-3-yl)amine;5-Amino-1-phenyl-1H-pyrazole
CBNumber: CB5416480
Molecular Formula: C9H9N3
Formula Weight: 159.19
MOL File: 826-85-7.mol

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5-AMINO-1-PHENYLPYRAZOLE Property

Melting point:: 51°C
Boiling point:: 123-130 °C(Press: 0.2 Torr)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 3.17±0.10(Predicted)
color: White to Light Orange-Yellow
InChI: InChI=1S/C9H9N3/c10-9-6-7-11-12(9)8-4-2-1-3-5-8/h1-7H,10H2
InChIKey: ZVNYYNAAEVZNDW-UHFFFAOYSA-N
SMILES: N1(C2=CC=CC=C2)C(N)=CC=N1

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
RTECS: UQ6108000
HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A0174
Product name: 5-Amino-1-phenylpyrazole
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $194
Updated: 2025/07/31

TCI Chemical

Product number: A0174
Product name: 5-Amino-1-phenylpyrazole
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $608
Updated: 2025/07/31

TRC

Product number: A626220
Product name: 5-Amino-1-phenylpyrazole
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Ark Pharm

Product number: P000715491
Product name: 1-Phenyl-1H-pyrazol-5-amine
Purity: 97%
Packaging: 1g
Price: $23
Updated: 2021/12/16

AK Scientific

Product number: J95305
Product name: 1-Phenyl-1H-pyrazol-5-amine
Packaging: 1g
Price: $25
Updated: 2021/12/16

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5-AMINO-1-PHENYLPYRAZOLE Chemical Properties,Usage,Production

Uses

5-Amino-1-phenylpyrazole is a reagent that is used in the synthesis of sulfaphenazole(S689020) derivatives as inhibitors and tools for comparing active sites of human liver cytochromes P 450 2C subfamily.

Synthesis

16078-71-0

826-85-7

General procedure for the synthesis of 5-amino-1-phenylpyrazole-4-carboxylic acid from ethyl 5-amino-1-phenylpyrazole-4-carboxylate: Step 1: Synthesis of 1-phenyl-1H-pyrazol-5-amine (F1) 5-Amino-4-ethoxy-1-phenylpyrazole (1 eq.) was dissolved in 36% hydrochloric acid solution (30 eq.) and the reaction mixture was stirred under reflux conditions overnight. After completion of the reaction, the mixture was cooled to room temperature, slowly poured into ice water and the pH was adjusted to basic with ammonia. The mixture was extracted with dichloromethane (3 times) and the organic phases were combined. The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to remove the solvent to give a light yellow oily product in 94% yield. Mass spectrometry (electrospray positive ionization mode): the theoretical molecular weight of C9H9N3 was 159, and the measured value was 160 (M+H)+.

References

[1] Patent: WO2010/23480, 2010, A1. Location in patent: Page/Page column 48
[2] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 18, p. 4492 - 4498
[3] Journal of the Brazilian Chemical Society, 2018, vol. 29, # 1, p. 159 - 167
[4] Patent: US2858309, 1957,
[5] Helvetica Chimica Acta, 1958, vol. 41, p. 306,309

5-AMINO-1-PHENYLPYRAZOLE Preparation Products And Raw materials

Raw materials

Ethanol Triethyl orthoformate Ethyl acetate Hydrochloric acid Sodium hydroxide Phenylhydrazine PETROLEUM ETHER Ethyl cyanoacetate

Preparation Products

SULFAPHENAZOLE

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5-AMINO-1-PHENYLPYRAZOLE Suppliers

Americas 1 Belgium 1 China 77 Europe 1 Germany 3 India 3 Japan 1 United Kingdom 6 United States 12 Global 105

Zhongshan Jukemei Biotechnology Co., Ltd.

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Energy Chemical

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Maya High Purity Chemicals

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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View Lastest Price from 5-AMINO-1-PHENYLPYRAZOLE manufacturers

Career Henan Chemical Co

Product: 5-AMINO-1-PHENYLPYRAZOLE 826-85-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons/month
Release date: 2020-01-09

826-85-7, 5-AMINO-1-PHENYLPYRAZOLERelated Search:

5-AMINO-1-PHENYLPYRAZOLE SULFAPHENAZOLE 5-AMINO-1-PHENYLPYRAZOLE-4-CARBONITRILE,5-Amino-1-phenylpyrazole-4-carbonitrile ,98% 5-AMINO-1-(4-NITROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 5-Amino-3-methyl-1-phenylpyrazole 5-AMINO-4-CYANO-3-CYANOMETHYL-1-PHENYLPYRAZOLE 5-AMINO-1-(4-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 5-AMINO-1-PHENYLPYRAZOLE-4-CARBOXAMIDE ETHYL 5-AMINO-1-PHENYLPYRAZOLE-4-CARBOXYLATE,5-amino-1-phenylpyrazole-4-carboxylic acid ethyl ester Acid Yellow 49 3-AMINO-5-PHENYLPYRAZOLE,5-AMINO-3-PHENYLPYRAZOLE,5-Amino-3-phenylpyrazole ,98% PP3 3-AMINO-4-PHENYLPYRAZOLE 5-AMINO-1-PHENYL-1H-PYRAZOLE-4-CARBOXYL& 1-PHENYLPYRAZOLE 5-AMINO-1-(2,4-DICHLOROPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 1-PHENYL-5-(1H-PYRROL-1-YL)-1H-PYRAZOLE-4-CARBONITRILE 2-(3-CHLORO-PHENYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE

5-AMINO-1-PHENYLPYRAZOLE

BUTTPARK 23\09-46

1-phenyl-1h-pyrazol-5-amin

5-amino-1-phenyl-pyrazol

1-phenylpyrazol-5-ylamine

Aminophenylpyrazole

5-AMINO-1-PHENYLPYRAZOLE 98+% T

1-Phenyl-1H-pyrazol-5-amine

2-Phenyl-3-amino-2H-pyrazole

3-Amino-2-phenyl-2H-pyrazole

5-Amino-1-phenyl-1H-pyrazole

(2-phenylpyrazol-3-yl)amine

2-phenylpyrazol-3-amine

5-Amino-1-phenylpyrazole &gt

1H-Pyrazol-5-amine, 1-phenyl-

1-phenyl-1H-pyrazole-5-amine

1-Phenyl-1H-pyrazol-5-ylamine

826-85-7