ChemicalBook > CAS DataBase List > AC-IEPD-AMC

AC-IEPD-AMC

Product Name
AC-IEPD-AMC
CAS No.
216757-33-4
Chemical Name
AC-IEPD-AMC
Synonyms
AC-IEPD-AMC;AC-ILE-GLU-PRO-ASP-AMC;GRANZYME B SUBSTRATE IX, FLUOROGENIC;AC-ILE-GLU-PRO-ASP-7-AMINO-4-METHYLCOUMARIN;N-ACETYL-ILE-GLU-PRO-ASP-7-AMIDO-4-METHYLCOUMARIN;N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine;L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alpha-asparagine
CBNumber
CB7411126
Molecular Formula
C32H41N5O11
Formula Weight
671.69
MOL File
216757-33-4.mol
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AC-IEPD-AMC Property

Boiling point:
1116.0±65.0 °C(Predicted)
Density 
1.366±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO/DMF: 1 mg/mL
form 
powder
pka
4.12±0.10(Predicted)
Sequence
Ac-Ile-Glu-Pro-Asp-{AMC}
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A6220
Product name
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin
Purity
≥97% (HPLC), powder
Packaging
5MG
Price
$589
Updated
2025/07/31
Biosynth Carbosynth
Product number
FA110586
Product name
Ac-Ile-Glu-Pro-Asp-AMC
Packaging
25mg
Price
$913
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004282
Product name
N-ACETYL-ILE-GLU-PRO-ASP-7-AMIDO-4-METHYLCOUMARIN
Purity
95.00%
Packaging
5MG
Price
$965.58
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110586
Product name
Ac-Ile-Glu-Pro-Asp-AMC
Packaging
50mg
Price
$1588
Updated
2021/12/16
AK Scientific
Product number
2795DC
Product name
Ac-Ile-Glu-Pro-Asp-AMC
Packaging
50mg
Price
$2193
Updated
2021/12/16
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AC-IEPD-AMC Chemical Properties,Usage,Production

Uses

Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

References

[1] Scott JI, et, al. A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5699-5703. DOI:10.1002/anie.202011429

AC-IEPD-AMC Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-IEPD-AMC Suppliers

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216757-33-4, AC-IEPD-AMCRelated Search:

GRANZYME B AC-ALA-ALA-PRO-ALA-AMC AC-IEPD-AFC AC-IEPD-AMC L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE DABCYL-LYS-HCOV-SARS REPLICASE POLYPROTEIN 1AB (3235-3246)-GLU-EDANS MCA-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-LYS(DNP)-ARG-ARG-NH2 Ac-Val-Arg-Pro-Arg-AMC DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE PGLU-GLY-ARG P-NITROANILIDE HYDROCHLORID MCA-GLY-LYS-PRO-ILE-LEU-PHE-PHE-ARG-LEU-LYS(DNP)-D-ARG-NH2 MCA-ARG-PRO-LYS-PRO-TYR-ALA-NVA-TRP-MET-LYS(DNP)-NH2 SUC-ALA-ALA-ALA-AMC

  • N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alpha-asparagine
  • GRANZYME B SUBSTRATE IX, FLUOROGENIC
  • AC-IEPD-AMC
  • AC-ILE-GLU-PRO-ASP-7-AMINO-4-METHYLCOUMARIN
  • N-ACETYL-ILE-GLU-PRO-ASP-7-AMIDO-4-METHYLCOUMARIN
  • AC-ILE-GLU-PRO-ASP-AMC
  • L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
  • N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine
  • 216757-33-4
  • C32H41N5O11
  • Pepetides