ChemicalBook > CAS DataBase List > AC-IEPD-AMC
AC-IEPD-AMC
- Product Name
- AC-IEPD-AMC
- CAS No.
- 216757-33-4
- Chemical Name
- AC-IEPD-AMC
- Synonyms
- AC-IEPD-AMC;AC-ILE-GLU-PRO-ASP-AMC;GRANZYME B SUBSTRATE IX, FLUOROGENIC;AC-ILE-GLU-PRO-ASP-7-AMINO-4-METHYLCOUMARIN;N-ACETYL-ILE-GLU-PRO-ASP-7-AMIDO-4-METHYLCOUMARIN;N-Acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine;L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-prolyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alpha-asparagine
- CBNumber
- CB7411126
- Molecular Formula
- C32H41N5O11
- Formula Weight
- 671.69
- MOL File
- 216757-33-4.mol
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AC-IEPD-AMC Property
- Boiling point:
- 1116.0±65.0 °C(Predicted)
- Density
- 1.366±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMSO/DMF: 1 mg/mL
- form
- powder
- pka
- 4.12±0.10(Predicted)
- Sequence
- Ac-Ile-Glu-Pro-Asp-{AMC}
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- A6220
- Product name
- N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin
- Purity
- ≥97% (HPLC), powder
- Packaging
- 5MG
- Price
- $589
- Updated
- 2025/07/31
Biosynth Carbosynth
- Product number
- FA110586
- Product name
- Ac-Ile-Glu-Pro-Asp-AMC
- Packaging
- 2mg
- Price
- $132
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110586
- Product name
- Ac-Ile-Glu-Pro-Asp-AMC
- Packaging
- 5mg
- Price
- $263
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110586
- Product name
- Ac-Ile-Glu-Pro-Asp-AMC
- Packaging
- 10mg
- Price
- $457
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA110586
- Product name
- Ac-Ile-Glu-Pro-Asp-AMC
- Packaging
- 25mg
- Price
- $913
- Updated
- 2021/12/16
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AC-IEPD-AMC Chemical Properties,Usage,Production
Uses
Ac-IEPD-AMC is a fluorogenic substrate for the determination of protease activity. Ac-IEPD-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
References
[1] Scott JI, et, al. A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5699-5703. DOI:10.1002/anie.202011429
AC-IEPD-AMC Preparation Products And Raw materials
Raw materials
Preparation Products
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AC-IEPD-AMC Suppliers
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216757-33-4, AC-IEPD-AMCRelated Search:
GRANZYME B
AC-ALA-ALA-PRO-ALA-AMC
AC-IEPD-AFC
AC-IEPD-AMC
L-PYROGLUTAMYL-L-ARGINYL-L-THREONYL-L-LYSYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
DABCYL-LYS-HCOV-SARS REPLICASE POLYPROTEIN 1AB (3235-3246)-GLU-EDANS
MCA-SER-GLU-VAL-ASN-LEU-ASP-ALA-GLU-PHE-ARG-LYS(DNP)-ARG-ARG-NH2
Ac-Val-Arg-Pro-Arg-AMC
DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS
BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE
PGLU-GLY-ARG P-NITROANILIDE HYDROCHLORID
MCA-GLY-LYS-PRO-ILE-LEU-PHE-PHE-ARG-LEU-LYS(DNP)-D-ARG-NH2
MCA-ARG-PRO-LYS-PRO-TYR-ALA-NVA-TRP-MET-LYS(DNP)-NH2
SUC-ALA-ALA-ALA-AMC