DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS

Product Name: DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS
CAS No.: 161877-70-9
Chemical Name: DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS
Synonyms: ICE SUBSTRATE II;DABCYL-YVADAPV-EDANS;CASPASE 1 (ICE) SUBSTRATE;IL-1B CONVERTING ENZYME SUBSTRATE II;DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS;IL-1-BETA CONVERTING ENZYME SUBSTRATE II;Caspase 1 (ICE) substrate for FRET assays;INTERLEUKIN-1BETA CONVERTING ENZYME SUBSTRATE II;DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt;4-(4-DIMETHYLAMINOPHENYLAZO)BENZOYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-5-[(2-AMINOETHYL)AMINO]-NAPHTHALENE-1-SULFONIC ACID
CBNumber: CB4308586
Molecular Formula: C61H76N12O14S
Formula Weight: 1233.39
MOL File: 161877-70-9.mol

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DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS Property

Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: -15°C
solubility: 5% NH3 (Aqueous): 1 mg/ml
form: A lyophilized powder
pka: -0.26±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24993
Product name: Dabcyl-YVADAPV-EDANS
Purity: ≥95%
Packaging: 1mg
Price: $242
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FD110900
Product name: DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt
Packaging: 100ug
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD110900
Product name: DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt
Packaging: 250ug
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD110900
Product name: DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt
Packaging: 500ug
Price: $310
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD110900
Product name: DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt
Packaging: 1mg
Price: $541
Updated: 2021/12/16

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DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS Chemical Properties,Usage,Production

Description

Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1. EDANS is released upon enzymatic cleavage by caspase-1 at the Ala-Ser site, of which the fluorescence can be used to quantify caspase-1 activity.

Uses

Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1].

References

[1] Schulz JB, et al. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J Neurosci. 1996 Aug 1;16(15):4696-706. DOI:10.1523/JNEUROSCI.16-15-04696.1996

Sequene

Dabcyl-Tyr-Val-Ala-Asp-Ala-Pro-Val-edans

DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS Preparation Products And Raw materials

Raw materials

Preparation Products

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DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS Suppliers

China 33 South Korea 1 United Kingdom 1 United States 6 Global 41

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161877-70-9, DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANSRelated Search:

CALCIUM-LIKE PEPTIDE Dentonin H-TYR-CYS-TRP-SER-GLN-TYR-LEU-CYS-TYR-OH COG-1410 HNGF6A -Defensin-2 (human) (trifluoroacetate salt) L-Glutamine, L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-threonyl- L-Cysteine, L-cysteinylglycyl-L-asparaginyl-L-lysyl-L-arginyl-L-threonyl-L-arginylglycyl-, cyclic (1→9)-disulfide C-PEPTIDE 2 (RAT) 4-DIMETHYLAMINO-4'-METHYLAZOBENZENE 1,5-EDANS BZ-PHE-NH2 BZ-TYR-VAL-NH2 AC-YVAD-CHO 4-amino-N-(2-phenylethyl)benzamide DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS BZ-TYR-NH2 Caspase 1, beta (Interleukin-1 Beta Converting Enzyme, ICE) Substrate II [DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS]

CASPASE 1 (ICE) SUBSTRATE

DABCYL-YVADAPV-EDANS

DABCYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-EDANS

ICE SUBSTRATE II

IL-1-BETA CONVERTING ENZYME SUBSTRATE II

IL-1B CONVERTING ENZYME SUBSTRATE II

4-(4-DIMETHYLAMINOPHENYLAZO)BENZOYL-TYR-VAL-ALA-ASP-ALA-PRO-VAL-5-[(2-AMINOETHYL)AMINO]-NAPHTHALENE-1-SULFONIC ACID

4-(4'-dimethylaminophenylazo)benzoyl-tyrosyl-valyl-alanyl-aspartyl-alanyl-prolyl-valyl-5((2-aminoethyl)amino)naphthalene-1-sulfonic acid

INTERLEUKIN-1BETA CONVERTING ENZYME SUBSTRATE II

Caspase 1 (ICE) substrate for FRET assays

DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt

L-Valinamide, N-[4-[[4-(dimethylamino)phenyl]azo]benzoyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]- (9CI)

L-Valinamide,N-[4-[[4-(dimethylamino)phenyl]azo]benzoyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N-[2-[(5-sulfo-1-naphthalenyl)amino]ethyl]-

161877-70-9

C61H76N12O14S

peptide