ChemicalBook > CAS DataBase List > -Defensin-2 (human) (trifluoroacetate salt)
-Defensin-2 (human) (trifluoroacetate salt)
- Product Name
- -Defensin-2 (human) (trifluoroacetate salt)
- CAS No.
- 372146-20-8
- Chemical Name
- -Defensin-2 (human) (trifluoroacetate salt)
- Synonyms
- Human β-defensin-2;-Defensin-2 (human) (trifluoroacetate salt)
- CBNumber
- CB24665692
- Molecular Formula
- C190H306F3N55O52S6
- Formula Weight
- 4442.1851496
- MOL File
- 372146-20-8.mol
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-Defensin-2 (human) (trifluoroacetate salt) Property
- Sequence
- Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro (Disulfide bridge:Cys8-Cys37; Cys15-Cys30; Cys20-Cys38)
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-Defensin-2 (human) (trifluoroacetate salt) Chemical Properties,Usage,Production
Uses
Human β-defensin-2 (HβD-2) is a small cysteine-rich cationic skin-antimicrobial peptide?(SAP) produced by a number of epithelial cells.Human β-defensin-2 has antimicrobial activity against gram-negative bacteria and Candida, but not gram-positive Staphylococcus aureus[1]. Human β-defensin-2 can be used for the study of colitis[2].
References
[1] J M Schr?der, et al. Human beta-defensin-2. Int J Biochem Cell Biol DOI:10.1016/s1357-2725(99)00013-8
[2] Louis Koeninger, et al. Human β-Defensin 2 Mediated Immune Modulation as Treatment for Experimental Colitis. Front Immunol. 2020 Jan 31;11:93. DOI:10.3389/fimmu.2020.00093
-Defensin-2 (human) (trifluoroacetate salt) Preparation Products And Raw materials
Raw materials
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