3-Methyl-2-pyridone
- Product Name
- 3-Methyl-2-pyridone
- CAS No.
- 1003-56-1
- Chemical Name
- 3-Methyl-2-pyridone
- Synonyms
- 3-Methylpyridin-2(1H)-one;2(1H)-Pyridinone, 3-methyl-;AKOS BBS-00002968;3-METHYL-2-PYRIDONE;3-Methyl-2-pyridinol;2-Hydroxy-3-picoline;3-METHYL-2-PYRIDINONE;2-Hydroxy-3-Piocoline;3-Methyl-2-pyridone>Anagrelide Impurity 39
- CBNumber
- CB7415881
- Molecular Formula
- C6H7NO
- Formula Weight
- 109.13
- MOL File
- 1003-56-1.mol
3-Methyl-2-pyridone Property
- Melting point:
- 139-141 °C
- Boiling point:
- 204.59°C (rough estimate)
- Density
- 1.1143 (rough estimate)
- refractive index
- 1.5444 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Soluble in methanol.
- pka
- 12.61±0.10(Predicted)
- form
- powder to crystal
- color
- White to Orange to Green
- BRN
- 1422044
- InChI
- InChI=1S/C6H7NO/c1-5-3-2-4-7-6(5)8/h2-4H,1H3,(H,7,8)
- InChIKey
- MVKDNXIKAWKCCS-UHFFFAOYSA-N
- SMILES
- C1(=O)NC=CC=C1C
- CAS DataBase Reference
- 1003-56-1(CAS DataBase Reference)
- NIST Chemistry Reference
- 2(1H)-pyridinone, 3-methyl-(1003-56-1)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-20/21/22-41-37/38-22
- Safety Statements
- 36/37/39-26-22-36
- WGK Germany
- 3
- HS Code
- 29333995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M1447
- Product name
- 3-Methyl-2-pyridone
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $124
- Updated
- 2025/07/31
- Product number
- M1447
- Product name
- 3-Methyl-2-pyridone
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $496
- Updated
- 2025/07/31
- Product number
- M337948
- Product name
- 3-Methylpyridin-2-ol
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- JK511717
- Product name
- 3-Methyl-2-pyridone
- Purity
- 98%
- Packaging
- 1g
- Price
- $33
- Updated
- 2021/12/16
- Product number
- 073936
- Product name
- 3-Methylpyridin-2(1H)-one
- Purity
- 95+%
- Packaging
- 5g
- Price
- $40
- Updated
- 2021/12/16
3-Methyl-2-pyridone Chemical Properties,Usage,Production
Chemical Properties
Light yellow needles
Uses
3-Methyl-2-pyridone, is used as a reactant with chloro-methoxy-methane to produce 1-methoxymethyl-3-methyl-1H-pyridin-2-one. This reaction will need reagent solvent CH2Cl2. The reaction time is 24 hours with ambient temperature
Definition
ChEBI: 3-Methyl-1,2-dihydropyridin-2-one is a member of methylpyridines.
Synthesis
3430-17-9
1003-56-1
GENERAL METHOD: In a dry Schlenk tube, 2-bromo-3-methylpyridine (5.98 g, 35.0 mmol) was dissolved in 100 mL of ammonia (Am-OH) and potassium tert-butanol (KOt-Bu, 39.3 g, 350.0 mmol) was added. The reaction mixture was stirred at 100 °C for 40 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in 50 mL of formic acid (HCO2H) and stirred at room temperature for 24 hours. Subsequently, the pH was adjusted to about 6 using 3N aqueous potassium hydroxide (KOH). extraction was carried out with chloroform (CHCl3, 3 x 50 mL), the organic phases were combined and washed with saturated saline, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated. The crude product was purified by column chromatography (eluent: 8% methanol/dichloromethane) to afford the target product 2-hydroxy-3-methylpyridine (1) as a white solid with a yield of 2.75 g in 72% yield.
References
[1] Synlett, 2015, vol. 26, # 11, p. 1557 - 1562
3-Methyl-2-pyridone Preparation Products And Raw materials
Raw materials
Preparation Products
3-Methyl-2-pyridone Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 3-Methyl-2-pyridone manufacturers
- Product
- 3-Methyl-2-pyridone 1003-56-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-14
- Product
- 3-Methyl-2-pyridinol 1003-56-1
- Price
- US $0.00/gm
- Min. Order
- 100gm
- Purity
- 99%min
- Supply Ability
- 100kgs
- Release date
- 2024-09-04
- Product
- 3-Methyl-2-pyridone 1003-56-1
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09