1,6-Dibromohexane
- Product Name
- 1,6-Dibromohexane
- CAS No.
- 629-03-8
- Chemical Name
- 1,6-Dibromohexane
- Synonyms
- 1,6-Dibromhexan;6-Dibromohexane;1,6-Dibromohexan;1,6-dibromo-hexan;1,6-Dibromotexane;1,6-DIBROMOHEXANE;Dibromo-1,6 hexane;Hexane,1,6-dibromo-;1,6-DIBROMO-N-HEXANE;1,6-Dibromohexane,98%
- CBNumber
- CB7435155
- Molecular Formula
- C6H12Br2
- Formula Weight
- 243.97
- MOL File
- 629-03-8.mol
1,6-Dibromohexane Property
- Melting point:
- -2-2.5 °C (lit.)
- Boiling point:
- 243 °C (lit.)
- Density
- 1.586 g/mL at 25 °C (lit.)
- vapor pressure
- <1 hPa (20 °C)
- refractive index
- n20/D 1.507(lit.)
- Flash point:
- 110 °C
- storage temp.
- Store below +30°C.
- solubility
- soluble in Chloroform, Ethyl Acetate
- form
- Liquid
- color
- colorless to brownish-yellow
- Water Solubility
- insoluble
- BRN
- 1236322
- Dielectric constant
- 8.8900000000000006
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- SGRHVVLXEBNBDV-UHFFFAOYSA-N
- CAS DataBase Reference
- 629-03-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Hexane, 1,6-dibromo-(629-03-8)
- EPA Substance Registry System
- Hexane, 1,6-dibromo- (629-03-8)
Safety
- Hazard Codes
- T,N,C
- Risk Statements
- 25-51/53-43
- Safety Statements
- 36-45-61-36/37
- RIDADR
- UN 2810 6.1/PG 3
- WGK Germany
- 3
- RTECS
- MO1515000
- TSCA
- Yes
- HazardClass
- 9
- PackingGroup
- III
- HS Code
- 29033036
- Toxicity
- LD50 orally in Rabbit: 1800 mg/kg LD50 dermal Rabbit > 2000 mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- D41007
- Product name
- 1,6-Dibromohexane
- Purity
- 96%
- Packaging
- 25g
- Price
- $20
- Updated
- 2025/07/31
- Product number
- D41007
- Product name
- 1,6-Dibromohexane
- Purity
- 96%
- Packaging
- 100g
- Price
- $40.6
- Updated
- 2025/07/31
- Product number
- 8.02921
- Product name
- 1,6-Dibromohexane
- Purity
- for synthesis
- Packaging
- 250ml
- Price
- $123
- Updated
- 2025/07/31
- Product number
- D0185
- Product name
- 1,6-Dibromohexane
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $18
- Updated
- 2025/07/31
- Product number
- D0185
- Product name
- 1,6-Dibromohexane
- Purity
- >97.0%(GC)
- Packaging
- 100g
- Price
- $28
- Updated
- 2025/07/31
1,6-Dibromohexane Chemical Properties,Usage,Production
Chemical Properties
colourless or pale yellow liquid. soluble in ethanol, ether, benzene and chloroform, insoluble in water. It is used in the synthesis of the hypotensive drug hexamethonium bromide.
Uses
1,6-Dibromohexane is used as a reagent in the synthesis of novel benzo[b]xanthone derivatives which have a potential antitumor activity. It is also used as a cross-linker for the cross-linking of glycuronans.
Uses
1,6-Dibromohexane is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are:
Synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications.
Synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.
Synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study redox switching behavior of single molecules.
Synthesis of water-soluble thermoresponsive polylactides.
Preparation
1,6-Dibromohexane is synthesized from hexanediol by bromination.
Synthesis
629-11-8
629-03-8
The general procedure for the synthesis of 1,6-dibromohexane from 1,6-hexanediol was as follows: N-bromosuccinimide (NBS, 534 mg, 3 mmol) was dissolved in dichloromethane (CH2Cl2, 10 mL) in a 50 mL round-bottomed flask. Triphenylphosphine (Ph3P, 786 mg, 3 mmol) and 1,6-hexanediol (1 mmol) were added dropwise to the NBS solution at -78 °C. The reaction mixture was stirred at room temperature away from light for 12 h, during which the progress of the reaction was monitored by thin layer chromatography (TLC, eluent: petroleum ether-ethyl acetate, 20:1). Upon completion of the reaction, the mixture was concentrated under vacuum and purified by fast chromatography on silica gel column (eluent: petroleum ether-ethyl acetate, 30:1) to afford the target product 1,6-dibromohexane.
References
[1] Synthesis (Germany), 2015, vol. 47, # 8, p. 1154 - 1162
[2] Journal of the American Chemical Society, 1936, vol. 58, p. 488
[3] Archiv der Pharmazie (Weinheim, Germany), 1935, p. 323
[4] Zhurnal Obshchei Khimii, 1935, vol. 5, p. 1508
[5] Journal of the Chemical Society, 1948, p. 46
1,6-Dibromohexane Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,6-Dibromohexane manufacturers
- Product
- 1,6-Dibromohexane 629-03-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-01-13
- Product
- 1,6-Dibromohexane 629-03-8
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25
- Product
- 1,6-Dibromohexane 629-03-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-13