ANHYDROTETRACYCLINE HYDROCHLORIDE
- Product Name
- ANHYDROTETRACYCLINE HYDROCHLORIDE
- CAS No.
- 13803-65-1
- Chemical Name
- ANHYDROTETRACYCLINE HYDROCHLORIDE
- Synonyms
- AnhydrotetracyclineHCl;Tetracycline Anhydro HCl;Aureomycin EP impurity J;Anhydrotetracycline HCl, EvoPure;ANHYDROTETRACYCLINE HYDROCHLORIDE;Anhydrotetracycline hydrochloride CRS;5A,6-ANHYDROTETRACYCLINEHYDROCHLORIDE;Anhydrotetracycline hydrochloride ,97%;ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP;Lymecycline Impurity 3(Lymecycline EP Impurity C)
- CBNumber
- CB7438626
- Molecular Formula
- C22H23ClN2O7
- Formula Weight
- 462.88
- MOL File
- 13803-65-1.mol
ANHYDROTETRACYCLINE HYDROCHLORIDE Property
- Melting point:
- 223 °C
- RTECS
- QI7860000
- storage temp.
- Refrigerator
- solubility
- Soluble in ethanol, DMSO, or DMF
- form
- Powder
- color
- Yellow to bright yellow
- Sensitive
- Moisture Sensitive
- BRN
- 4228856
- Stability:
- Hygroscopic
- EPA Substance Registry System
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4S,4aS,12aS)- (13803-65-1)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 63-36
- Safety Statements
- 36/37/39-26
- WGK Germany
- 3
- HS Code
- 29413020
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P403Store in a well-ventilated place.
N-Bromosuccinimide Price
- Product number
- PHR3175
- Product name
- Anhydrotetracycline Hydrochloride
- Purity
- pharmaceutical secondary standard, certified reference material
- Packaging
- 50MG
- Price
- $534
- Updated
- 2024/03/01
- Product number
- 94664
- Product name
- Anhydrotetracycline hydrochloride
- Purity
- certified reference material, TraceCERT
- Packaging
- 10mg
- Price
- $296
- Updated
- 2024/03/01
- Product number
- 37919
- Product name
- Anhydrotetracycline hydrochloride
- Purity
- VETRANAL?, analytical standard
- Packaging
- 100mg
- Price
- $257
- Updated
- 2024/03/01
- Product number
- 1035708
- Product name
- Anhydrotetracycline hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25mg
- Price
- $1350
- Updated
- 2024/03/01
- Product number
- J66688
- Product name
- Anhydrotetracycline hydrochloride
- Packaging
- 10mg
- Price
- $66.2
- Updated
- 2024/03/01
ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties,Usage,Production
Description
The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-
Chemical Properties
yellow to bright yellow powder
Uses
A Tetracycline derivative exhibiting no antibiotic activity, a useful effector of tetracycline-dependent gene expression in bacterial expression systems.
Uses
Anhydrotetracycline is a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions to aromatise the B ring. Anhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, anhydrotetracycline is considered biologically active and is thought responsible for aspects of tetracycline toxicity.
Uses
Anhydrotetracycline hydrochloride is a salt of a degradation product of tetracycline, formed by dehydration at the C6 position under acidic conditions to aromatise the B ring. Anhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, anhydrotetracycline is considered biologically active and is thought responsible for aspects of tetracycline toxicity.