4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

Product Name: 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
CAS No.: 4465-65-0
Chemical Name: 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonyms: Epianhydrotetracycline;Aureomycin EP impurity K;Tetracycline EP Impurity D HCl;Tetracycline 4-Epi Anhydro HCl;Chlortetracycline EP Impurity I;Epianhydrotetracycline hydrochloride;4-Epianhydrotetracycline HCl, EvoPure;4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE;4-Epianhydroustetracycline hydrochloride;4-Epianhydrotetracycline hydrochloride CRS
CBNumber: CB9171671
Molecular Formula: C22H23ClN2O7
Formula Weight: 462.88
MOL File: 4465-65-0.mol

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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Property

Melting point:: 220 °C
storage temp.: -20°C Freezer
solubility: DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form: Powder
color: Orange
BRN: 3840711
EPA Substance Registry System: 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0)

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Safety

Hazard Codes: Xn
Risk Statements: 63-36-22
Safety Statements: 36/37/39-26
WGK Germany: 3
HS Code: 29413000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 37921
Product name: 4-Epianhydrotetracycline hydrochloride
Purity: VETRANAL?, analytical standard
Packaging: 100mg
Price: $311
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1236506
Product name: 4-Epianhydrotetracycline hydrochloride
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $1380
Updated: 2024/03/01

Cayman Chemical

Product number: 27954
Product name: Epianhydrotetracycline (hydrochloride)
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 27954
Product name: Epianhydrotetracycline (hydrochloride)
Packaging: 25mg
Price: $606
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHR1691
Product name: 4-Epianhydrotetracycline hydrochloride
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 100mg
Price: $705
Updated: 2024/03/01

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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

orange powder

Uses

Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.

Uses

An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Suppliers

Belgium 1 Canada 1 China 50 France 1 Germany 1 India 4 Japan 1 Switzerland 1 United Kingdom 2 United States 9 Global 71

J & K SCIENTIFIC LTD.

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Sinopharm Chemical Reagent Co,Ltd.

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Thermo Fisher Scientific

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ChemStrong Scientific Co.,Ltd

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Alta Scientific Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Beijing Solarbio Science & Tecnology Co., Ltd.

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Lynnchem

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4465-65-0, 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDERelated Search:

2,3-DIMETHYLNAPHTHALENE 1,3-DIMETHYLNAPHTHALENE 4-EPIANHYDROCHLORTETRACYCLINE HYDROCHLORIDE, CAN BE USED AS SECONDARY STANDARD 1'-HYDROXY-2'-ACETONAPHTHONE 2-ACETYL-1-TETRALONE 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE C-(1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-METHYLAMINE 2-Methyl-1-tetralone Naphthalen-2-ethanol 5-METHOXY-1-TETRALONE L-ISOLEUCINOL HCL 1,2-DIMETHYLNAPHTHALENE ANHYDROTETRACYCLINE HYDROCHLORIDE Tetracycline 1,2,3-TRIMETHYLNAPHTHALENE 5-Methylnaphthalene-1-ol 4-EPIANHYDROTETRACYCLINE 1-M-TOLYL-PENTAN-1-ONE

4-epianhydrotetracyclinehydrochloride’canbeusedassecondarystandard’

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

Lymecycline Impurity 4（Lymecycline EP Impurity D）

Tetracycline EP Impurity D HCl

(4R,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE

4-Epianhydrotetracycline hydrochloride, 'can be used as a secondary standard', 97%

4-Epianhydroustetracycline hydrochloride

4-Epianhydrotetracycline hydrochloride,97%,'can be used as a secondary standard'

4-Epianhydrotetracycline Hydrochloride (50 mg)

(4R,4aS,12aS)-4-(DiMethylaMino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-Methyl-1,12-dioxo-2-naphthacenecarboxaMide Hydrochloride

Epianhydrotetracycline hydrochloride

4-Epianhydrotetracycline hydrochloride CRS

Tetracycline 4-Epi Anhydro HCl

Chlortetracycline EP Impurity I

Aureomycin EP impurity K

Epianhydrotetracycline

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP

4-Epianhydrotetracycline Hydrochloride (1236506)

(4R,4aS,12aS)-4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide (4-epianhydrotetracycline)

4-Epianhydrotetracycline HCl, EvoPure

4-epi-Anhydrotetracycline hydrochloride in methanol

C13174500 4-EpianhydrotetracyclinEhydrochlor

Tetracycline EP Impurity D (Chlortetracycline EP Impurity I, Lymecycline EP Impurity D, 4-Epianhydrotetracycline)

4465-65-0

C22H22N2O7HCl

C22H23ClN2O7

Intermediates & Fine Chemicals

Pharmaceuticals