ChemicalBook > CAS DataBase List > 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

Product Name
4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
CAS No.
4465-65-0
Chemical Name
4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonyms
Epianhydrotetracycline;Aureomycin EP impurity K;Tetracycline Impurity D(EP);Tetracycline EP Impurity D HCl;Tetracycline 4-Epi Anhydro HCl;Chlortetracycline EP Impurity I;Epianhydrotetracycline hydrochloride;4-Epianhydrotetracycline HCl, EvoPure;4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE;4-Epianhydroustetracycline hydrochloride
CBNumber
CB9171671
Molecular Formula
C22H23ClN2O7
Formula Weight
462.88
MOL File
4465-65-0.mol
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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Property

Melting point:
220 °C
storage temp. 
-20°C Freezer
solubility 
DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form 
Powder
color 
Orange
BRN 
3840711
InChIKey
XBSQEFHDCDFNJU-PFRKANOHNA-N
SMILES
O[C@@]12C(C(C(=O)N)=C(O)[C@H](N(C)C)[C@]1([H])CC1C(=C3C=CC=C(O)C3=C(O)C=1C2=O)C)=O.Cl |&1:1,9,13,r|
EPA Substance Registry System
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
63-36-22
Safety Statements 
36/37/39-26
WGK Germany 
3
HS Code 
29413000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E0400000
Product name
4-Epianhydrotetracycline hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
25 mg
Price
$225
Updated
2025/07/31
Sigma-Aldrich
Product number
37921
Product name
4-Epianhydrotetracycline hydrochloride
Purity
VETRANAL?, analytical standard
Packaging
100mg
Price
$221.9
Updated
2025/07/31
Sigma-Aldrich
Product number
1236506
Product name
4-Epianhydrotetracycline hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1200
Updated
2025/07/31
Cayman Chemical
Product number
27954
Product name
Epianhydrotetracycline (hydrochloride)
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
27954
Product name
Epianhydrotetracycline (hydrochloride)
Packaging
25mg
Price
$606
Updated
2024/03/01
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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

orange powder

Uses

Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.

Uses

An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Suppliers

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View Lastest Price from 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE 4465-65-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-08

4465-65-0, 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDERelated Search:


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  • (4R,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE
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  • 4-Epianhydrotetracycline Hydrochloride (50 mg)
  • (4R,4aS,12aS)-4-(DiMethylaMino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-Methyl-1,12-dioxo-2-naphthacenecarboxaMide Hydrochloride
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  • 4-Epianhydrotetracycline Hydrochloride (1236506)
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  • TETRACYCLINE EP IMPURITY D/ 4-EPIANHYDRO TETRACYCLINE HYDROCHLORIDE
  • 4-Epianhydrotetracycline hydrochloride RS
  • Tetracycline Impurity D(EP)
  • 4465-65-0
  • C22H22N2O7HCl
  • C22H23ClN2O7
  • Intermediates & Fine Chemicals
  • Pharmaceuticals