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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE

Product Name
4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
CAS No.
4465-65-0
Chemical Name
4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
Synonyms
Epianhydrotetracycline;Aureomycin EP impurity K;Tetracycline EP Impurity D HCl;Tetracycline 4-Epi Anhydro HCl;Chlortetracycline EP Impurity I;Epianhydrotetracycline hydrochloride;4-Epianhydrotetracycline HCl, EvoPure;4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE;4-Epianhydroustetracycline hydrochloride;4-Epianhydrotetracycline hydrochloride CRS
CBNumber
CB9171671
Molecular Formula
C22H23ClN2O7
Formula Weight
462.88
MOL File
4465-65-0.mol
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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Property

Melting point:
220 °C
storage temp. 
-20°C Freezer
solubility 
DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 2 mg/ml; PBS (pH 7.2): 0.25 mg/ml
form 
Powder
color 
Orange
BRN 
3840711
EPA Substance Registry System
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, hydrochloride (1:1), (4R,4aS,12aS)- (4465-65-0)
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Safety

Hazard Codes 
Xn
Risk Statements 
63-36-22
Safety Statements 
36/37/39-26
WGK Germany 
3
HS Code 
29413000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
37921
Product name
4-Epianhydrotetracycline hydrochloride
Purity
VETRANAL?, analytical standard
Packaging
100mg
Price
$311
Updated
2024/03/01
Sigma-Aldrich
Product number
1236506
Product name
4-Epianhydrotetracycline hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$1380
Updated
2024/03/01
Cayman Chemical
Product number
27954
Product name
Epianhydrotetracycline (hydrochloride)
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
27954
Product name
Epianhydrotetracycline (hydrochloride)
Packaging
25mg
Price
$606
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR1691
Product name
4-Epianhydrotetracycline hydrochloride
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100mg
Price
$705
Updated
2024/03/01
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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

orange powder

Uses

Epianhydrotetracycline is a secondary degradation product formed by epimerisation of tetracycline and dehydration at the C6 position to aromatise the B ring. Epianhydrotetracycline is an important standard for monitoring tetracycline stability. Although the degradation is associated with a loss of antibiotic activity, epianhdrotetracycline is considered biologically active and is thought responsible for aspects tetracycline toxicity.

Uses

An antibiotic derived from Tetracycline. Studies have shown that this derivative can have a 250-fold higher toxicity depending on the system under study.

4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE Suppliers

Belgium 1 Canada 1 China 49 France 1 Germany 1 India 4 Japan 1 Switzerland 1 United Kingdom 2 United States 9 Global 70
Dr. Ehrenstorfer GmbH
Tel
--
Fax
--
Email
info@analytical-standards.com
Country
Germany
ProdList
5545
Advantage
66

4465-65-0, 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDERelated Search:

2,3-DIMETHYLNAPHTHALENE 1,3-DIMETHYLNAPHTHALENE 4-EPIANHYDROCHLORTETRACYCLINE HYDROCHLORIDE, CAN BE USED AS SECONDARY STANDARD 1'-HYDROXY-2'-ACETONAPHTHONE 2-ACETYL-1-TETRALONE 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE C-(1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-METHYLAMINE 2-Methyl-1-tetralone Naphthalen-2-ethanol 5-METHOXY-1-TETRALONE L-ISOLEUCINOL HCL 1,2-DIMETHYLNAPHTHALENE ANHYDROTETRACYCLINE HYDROCHLORIDE Tetracycline 1,2,3-TRIMETHYLNAPHTHALENE 5-Methylnaphthalene-1-ol 4-EPIANHYDROTETRACYCLINE 1-M-TOLYL-PENTAN-1-ONE

  • 4-epianhydrotetracyclinehydrochloride’canbeusedassecondarystandard’
  • 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE
  • Lymecycline Impurity 4（Lymecycline EP Impurity D）
  • Tetracycline EP Impurity D HCl
  • (4R,4AS,12AS)-4-(DIMETHYLAMINO)-1,4,4A,5,12,12A-HEXAHYDRO-3,10,11,12A-TETRAHYDROXY-6-METHYL-1,12-DIOXO-2-NAPHTHACENECARBOXAMIDE MONOHYDROCHLORIDE
  • 4-Epianhydrotetracycline hydrochloride, 'can be used as a secondary standard', 97%
  • 4-Epianhydroustetracycline hydrochloride
  • 4-Epianhydrotetracycline hydrochloride,97%,'can be used as a secondary standard'
  • 4-Epianhydrotetracycline Hydrochloride (50 mg)
  • (4R,4aS,12aS)-4-(DiMethylaMino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-Methyl-1,12-dioxo-2-naphthacenecarboxaMide Hydrochloride
  • Epianhydrotetracycline hydrochloride
  • 4-Epianhydrotetracycline hydrochloride CRS
  • Tetracycline 4-Epi Anhydro HCl
  • Chlortetracycline EP Impurity I
  • Aureomycin EP impurity K
  • Epianhydrotetracycline
  • 4-EPI-ANHYDROTETRACYCLINE HYDROCHLORIDE USP/EP/BP
  • 4-Epianhydrotetracycline Hydrochloride (1236506)
  • (4R,4aS,12aS)-4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide (4-epianhydrotetracycline)
  • Tetracycline EP Impurity D (Chlortetracycline EP Impurity I, Lymecycline EP Impurity D, 4-Epianhydrotetracycline)
  • 4-Epianhydrotetracycline HCl, EvoPure
  • 4-epi-Anhydrotetracycline hydrochloride in methanol
  • C13174500 4-EpianhydrotetracyclinEhydrochlor
  • 4465-65-0
  • C22H22N2O7HCl
  • C22H23ClN2O7
  • Intermediates & Fine Chemicals
  • Pharmaceuticals