3-Aminofurazan-4-carboxylic acid
Uses- Product Name
- 3-Aminofurazan-4-carboxylic acid
- CAS No.
- 78350-50-2
- Chemical Name
- 3-Aminofurazan-4-carboxylic acid
- Synonyms
- TIMTEC-BB SBB000060;3-amino-4-carboxyfuran;3-amino-4-carboxyfurazan;3-AMINOFURAZAN-4-CARBOXYLIC ACID;4-AMINO-3-FURAZANECARBOXYLIC ACID;5-AMINOFURAZANE-4-CARBOXYLIC ACID;4-AMINO-FURAZAN-3-CARBOXYLIC ACID;4-Amino-1,2,5-oxadiazole-3-carboxylicaci;4-Amino-1,2,5-oxadiazol-3-carboxylic acid;4-AMINO-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID
- CBNumber
- CB7441817
- Molecular Formula
- C3H3N3O3
- Formula Weight
- 129.07
- MOL File
- 78350-50-2.mol
3-Aminofurazan-4-carboxylic acid Property
- Melting point:
- 216-217 °C(Solv: water (7732-18-5))
- Boiling point:
- 385.4±52.0 °C(Predicted)
- Density
- 1.756±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- 3.40±0.10(Predicted)
- Appearance
- Light brown to off-white Solid
- InChI
- InChI=1S/C3H3N3O3/c4-2-1(3(7)8)5-9-6-2/h(H2,4,6)(H,7,8)
- InChIKey
- YOXIXLVJYMCCIB-UHFFFAOYSA-N
- SMILES
- O1N=C(N)C(C(O)=O)=N1
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
N-Bromosuccinimide Price
- Product number
- B419178
- Product name
- 4-Amino-1,2,5-oxadiazole-3-carboxylicAcid
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 007819
- Product name
- 4-Amino-1,2,5-oxadiazole-3-carboxylic acid
- Packaging
- 1g
- Price
- $25
- Updated
- 2021/12/16
- Product number
- A920
- Product name
- 4-Amino-1,2,5-oxadiazole-3-carboxylicacid
- Packaging
- 1g
- Price
- $38
- Updated
- 2021/12/16
- Product number
- OR912026
- Product name
- 4-Amino-1,2,5-oxadiazole-3-carboxylicacid
- Purity
- 96%
- Packaging
- 1g
- Price
- $52
- Updated
- 2021/12/16
- Product number
- FA57184
- Product name
- 3-Aminofurazan-4-carboxylic acid
- Packaging
- 2g
- Price
- $60
- Updated
- 2021/12/16
3-Aminofurazan-4-carboxylic acid Chemical Properties,Usage,Production
Uses
3-Aminofuran-4-carboxylic acid is a carboxylic acid organic compound and an important intermediate in the synthesis of compounds such as furazan, oxyfuran, and pyrrolifuran.
Synthesis
105-56-6
78350-50-2
To a stirred suspension of ethyl cyanoacetate (28.3 g, 0.25 mol, 1.0 eq.) and sodium nitrite (17.3 g, 0.25 mol, 1.0 eq.) in a mixture of ethanol (17 mL) and water (200 mL) was added 85% phosphoric acid (10 mL) slowly and dropwise at 10-15°C with continuous stirring for 12 hours. Upon completion of the reaction, the reaction mixture was treated sequentially with sodium hydroxide (4 x 10 g, 1 mol, 4.0 eq.) and potassium hydroxide (2 x 14 g, 0.5 mol, 2.0 eq.). Hydroxylamine hydrochloride (NH2OH-HCl, 69.5 g, 1.0 mol, 4.0 eq.) was slowly added to the resulting solution at room temperature, followed by heating the reaction mixture to 95 °C and stirring for 2 hours. After completion of the reaction, it was cooled to room temperature and quenched with concentrated hydrochloric acid. The mixture was cooled to 0 °C and allowed to stand for 12 h to precipitate, the precipitate was collected by filtration and dried. The filtrate was extracted with ether (3 x 30 mL), the organic phases were combined and concentrated under reduced pressure. The concentrated residue was combined with the previously obtained precipitate and recrystallized from hot water to afford the target compound 4-amino-1,2,5-oxadiazole-3-carboxylic acid (21.3 g, 0.165 mol, 66% yield) as a white solid. The product was characterized by 1H-NMR (300 MHz, DMSO-d6), 13C-NMR (75 MHz, DMSO-d6) and HRMS (ESI), and the data were consistent with the expected structure.
References
[1] Patent: EP3305783, 2018, A1. Location in patent: Paragraph 0092; 0093
3-Aminofurazan-4-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Aminofurazan-4-carboxylic acid Suppliers
- Tel
- --
- Fax
- --
- sales@carbosynth.com
- Country
- United Kingdom
- ProdList
- 6005
- Advantage
- 58
- Tel
- --
- Fax
- --
- enquiries@keyorganics.ltd.uk
- Country
- United Kingdom
- ProdList
- 6663
- Advantage
- 50
- Tel
- --
- Fax
- --
- info@atlantic-chemicals.com
- Country
- United Kingdom
- ProdList
- 5618
- Advantage
- 63
- Tel
- --
- Fax
- --
- sales@zerenex-molecular.com
- Country
- United Kingdom
- ProdList
- 6204
- Advantage
- 47
View Lastest Price from 3-Aminofurazan-4-carboxylic acid manufacturers
- Product
- 3-Aminofurazan-4-carboxylic acid 78350-50-2
- Price
- US $1.60-6.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19
- Product
- 3-Aminofurazan-4-carboxylic acid 78350-50-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg;10kg;100kg
- Release date
- 2019-08-29