2,4-Dimethylphenylhydrazine hydrochloride
- Product Name
- 2,4-Dimethylphenylhydrazine hydrochloride
- CAS No.
- 60480-83-3
- Chemical Name
- 2,4-Dimethylphenylhydrazine hydrochloride
- Synonyms
- 2,4-DIMETHYLPHENYLHYDRAZINE HCL;2,4-Dimethylphenylhydrazine HCI;4-hydrazinyl-N,N-diMethylaniline;4-Hydrazino-m-xylene hydrochloride;1-(2,4-Dimethylphenyl)hydrazineHCl;2,4-DIMETHYLPHENYLHYDRAZINE HYDROCHLORIDE;2,4-Dimethylphenylhydrazine hydrochloride 98%;1-(2,4-DIMETHYLPHENYL)HYDRAZINE HYDROCHLORIDE;(2,4-Dimethylphenyl)hydrazine hydrochloride (1:1);2,4-Dimethylphenylhydrazine hydrochloride ISO 9001：2015 REACH
- CBNumber
- CB7443321
- Molecular Formula
- C8H13ClN2
- Formula Weight
- 172.66
- MOL File
- 60480-83-3.mol
2,4-Dimethylphenylhydrazine hydrochloride Property
- Melting point:
- 180 °C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- color
- Light beige/brown
- Sensitive
- Hygroscopic
- CAS DataBase Reference
- 60480-83-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36-36/37
- WGK Germany
- 3
- Hazard Note
- Harmful/Irritant
- HS Code
- 2928009090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- D460058
- Product name
- 2,4-Dimethylphenylhydrazine hydrochloride
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3739-5-Y1
- Product name
- 2,4-Dimethylphenylhydrazine hydrochloride
- Packaging
- 25g
- Price
- $47
- Updated
- 2021/12/16
- Product number
- 074330
- Product name
- 2,4-Dimethylphenylhydrazine hydrochloride
- Purity
- 95+%
- Packaging
- 100g
- Price
- $94
- Updated
- 2021/12/16
- Product number
- 074330
- Product name
- 2,4-Dimethylphenylhydrazine hydrochloride
- Purity
- 95+%
- Packaging
- 500mg
- Price
- $10
- Updated
- 2021/12/16
- Product number
- AK-35813
- Product name
- 2,4-Dimethylphenylhydrazine hydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
2,4-Dimethylphenylhydrazine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powde
Synthesis
95-68-1
60480-83-3
Example 13, Preparation of 2,4-dimethylphenylhydrazine hydrochloride (Compound 13): to a mixed solution of 2,4-dimethylaniline (35.4 mL; 36.3 g; 0.3 mol) cooled to 0 °C and concentrated hydrochloric acid (220 mL), aqueous sodium nitrite (20.6 g; 0.3 mol dissolved in 60 mL of water) was slowly added dropwise with a controlled rate of acceleration of dropwise addition to maintain the temperature of the reaction at a temperature not The rate of acceleration was controlled to maintain the reaction temperature not exceeding 5 °C. Upon completion of the reaction, the resulting solution was filtered and added to a solution of stannous chloride (124 g; 0.65 mol) in concentrated hydrochloric acid (124 mL) that had been pre-cooled to 5 °C with vigorous stirring. Subsequently, the resulting precipitate was separated by filtration, suspended in water (500 mL) and adjusted to pH 12 with sodium hydroxide solution (40%).The reaction mixture was extracted with ether (3 x 200 mL), the ether layers were combined and dried over anhydrous magnesium sulfate. The dried ether solution was passed through dry HCl gas until the precipitation was complete. The precipitate was collected by filtration, washed with ether and dried in a vacuum desiccator using phosphorus pentoxide as desiccant to give 2,4-dimethylphenylhydrazine hydrochloride (compound 13) in 18.5 g (35.8% yield). UV maximum absorption wavelength λmax 281 nm. mass spectrum (MALDI) (C8H12N2): measured value m/z 137.2, calculated value m/z 136.19. 1H-NMR (D2O), δ (ppm): 2.03 (3H, s, para-CH3), 2.08 (3H, s, o- CH3), 6.72 (1H, s, aryl ring H ), 6.93 (2H, d, aryl ring H).
References
[1] Patent: EP2157088, 2010, A1. Location in patent: Page/Page column 43-44
[2] Journal of Organic Chemistry, 2011, vol. 76, # 13, p. 5295 - 5308
[3] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 3, p. 529 - 532
[4] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 137 - 147
2,4-Dimethylphenylhydrazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
2,4-Dimethylphenylhydrazine hydrochloride Suppliers
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View Lastest Price from 2,4-Dimethylphenylhydrazine hydrochloride manufacturers
- Product
- 2,4-Dimethylphenylhydrazine hydrochloride 60480-83-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-11