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Sophoricoside

Product Name
Sophoricoside
CAS No.
152-95-4
Chemical Name
Sophoricoside
Synonyms
Sophomoric;ISOGENISTIN;SOPHORICOSIDE;Sophoricoside(P);Sophoricoside-RM;Sophoricoside >SOLSTITIALIN A(SH);Sophoricoside ,98%;Sophora glycosides;GENISTEIN-4'-GLUCOSIDE
CBNumber
CB7446261
Molecular Formula
C21H20O10
Formula Weight
432.38
MOL File
152-95-4.mol
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Sophoricoside Property

Melting point:
298°
alpha 
D20 -47° (pyridine); D20 -32° (10% aq pyridine)
Boiling point:
466.08°C (rough estimate)
Density 
1.3597 (rough estimate)
refractive index 
1.5376 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Aqueous Base (Slightly), DMSO (Slightly, Heated), Pyridine (Slightly, Sonicated)
pka
6.45±0.20(Predicted)
form 
Solid
color 
White to Light Brown
λmax
271nm(MeOH)(lit.)
InChIKey
ISQRJFLLIDGZEP-JNAFRSBINA-N
SMILES
C12C(O)=CC(O)=CC=1OC=C(C1C=CC(O[C@H]3[C@H](O)[C@H]([C@H](O)[C@@H](CO)O3)O)=CC=1)C2=O |&1:16,17,19,20,22,r|
CAS DataBase Reference
152-95-4(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00438
Product name
Sophoricoside
Purity
≥98% (HPLC)
Packaging
5 mg
Price
$161
Updated
2025/07/31
Sigma-Aldrich
Product number
SMB00438
Product name
Sophoricoside
Purity
≥98% (HPLC)
Packaging
25 mg
Price
$476
Updated
2025/07/31
TCI Chemical
Product number
S0835
Product name
Sophoricoside
Purity
>98.0%(HPLC)
Packaging
100mg
Price
$230
Updated
2025/07/31
Usbiological
Product number
300997
Product name
Sophoricoside
Packaging
20mg
Price
$276
Updated
2021/12/16
Usbiological
Product number
294604
Product name
Sophoricoside
Packaging
100mg
Price
$333
Updated
2021/12/16
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Sophoricoside Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Uses

Genistein 4''-β-D-glucopyranoside is a metabolite of Genistein (G350000), which exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation.

Definition

ChEBI: Sophoricoside is an isoflavonoid and an acrovestone.

Biological Activity

Sophoricoside (SOP) improves lipopolysaccharides (LPS)-induced acute lung injury (ALI) in mice by activating the adenosine monophosphate-activated protein kinase (AMPK)/nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. It also improves contact dermatitis by inhibiting the nuclear factor-kappa B (NF-KB) pathway in B cells in mice model.', 'Sophoricoside elicits anti-cancer, immunosuppressive, and anti-inflammatory activities. It inhibits proinflammatory cytokine production in human mast cells and has the potential to tre at allergic inflammation diseases.

in vivo

When the Sophoricoside is orally administered 1 h before compound 48/80 injections, the scratching behaviors is reduced. The inhibition rate of Sophoricoside (2 mg/kg) is approximately 41.21%. Orally administered Sophoricoside inhibits the scratching behaviors by 47.31%. When mice are treated for 2 weeks with Sophoricoside, the atopic dermatitis is recovered to a significant extent[1].

Sophoricoside Preparation Products And Raw materials

Raw materials

Preparation Products

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Sophoricoside Suppliers

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View Lastest Price from Sophoricoside manufacturers

BINBO BIOLOGICAL CO.,LTD
Product
Sophoricoside 152-95-4
Price
US $0.00/kg
Min. Order
1kg
Purity
10% 20% 98%
Supply Ability
1000 kg
Release date
2025-06-09
Shaanxi Xianhe Biotech Co., Ltd
Product
Sophoricoside 152-95-4
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000kg
Release date
2025-04-29
Changsha Staherb Natural Ingredients Co., Ltd.
Product
Sophoricoside 152-95-4
Price
US $80.00-750.00/kg
Min. Order
1kg
Purity
5%-98% HPLC
Supply Ability
10000KG
Release date
2022-09-19

152-95-4, SophoricosideRelated Search:

SOPHORIDINE Sophoridine Tea polyphenol Naringin Ginkgo biloba extract Polydatin Evodiamine PINOCEMBRIN CALYCOSIN Quercetin dihydrate Rotundine Tris(hydroxymethyl)nitromethane Solvent Red 43 Tangeretin Genistein 5,7-DIHYDROXYISOFLAVONE 5,4'-DIHYDROXY-7-METHOXYISOFLAVONE-4'-O-GLUCOSIDE Sophoricoside

  • 5,7-dihydroxy-3-[4-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]phenyl]-1-benzopyran-4-one
  • SOPHORICOSIDE
  • ISOGENISTIN
  • GENISTEIN-4'-GLUCOSIDE
  • GENISTEIN-4'-O-GLUCOSIDE
  • 4H-1-Benzopyran-4-one,3-[4-(β-
  • D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-
  • Sophoricoside ,98%
  • 3-[4-(β-D-Glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
  • SOLSTITIALIN A(SH)
  • Genistein 4'-Glucoside 4'-(beta-D-Glucopyranosyloxy)-5,7-dihydroxyisoflavone
  • 5,7-dihydroxy-3-[4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
  • 4'-beta-D-glucopyranosyloxy-5,7-dihydroxyisoflavone
  • Sophora glycosides
  • Sophoricoside 5,7-Dihydroxy-3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]chromen-4-one
  • Sophoricoside, 98%, from Sophora japonica Linn.
  • Sophoricoside &gt
  • Genistein 4'-β-D-glucopyranoside
  • Genistein sophoricoside
  • 4H-1-Benzopyran-4-one, 3-[4-(β-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-
  • Sophoricoside USP/EP/BP
  • 5,7-Dihydroxy-3-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-4H-chromen-4-one
  • Sophomoric
  • 4H-1-Benzopyran-4-one,3-[4-(b-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-
  • SOPHORICOSIDE(GENISTEIN-4'-GLUCOSIDE)
  • Sophoricoside(P)
  • Sophoricoside-RM
  • Sophoricoside, 10 mM in DMSO
  • Genistein 4'-beta-D-glucopyranoside
  • 152-95-4
  • 152-94-5
  • Miscellaneous Natural Products
  • Natural Plant Extract