ChemicalBook > CAS DataBase List > 1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE

1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE

Product Name
1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE
CAS No.
132414-50-7
Chemical Name
1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE
Synonyms
1-Benzylhexahydropyrrolo[3,4-b]pyrrole;1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE;octahydro-1-(phenylmethyl)-Pyrrolo[3,4-b]pyrrole;Pyrrolo[3,4-b]pyrrole, octahydro-1-(phenylmethyl)-;1-benzyl-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole;1-(phenylmethyl)-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole
CBNumber
CB7453687
Molecular Formula
C13H18N2
Formula Weight
202.3
MOL File
132414-50-7.mol
More
Less

1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE Property

Boiling point:
304.4±17.0 °C(Predicted)
Density 
1.074±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
10.80±0.20(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B285325
Product name
1-Benzyloctahydropyrrolo[3,4-b]pyrrole
Packaging
250mg
Price
$145
Updated
2021/12/16
AK Scientific
Product number
X9831
Product name
1-Benzyloctahydropyrrolo[3,4-b]pyrrole
Packaging
1g
Price
$159
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB143062
Product name
1-Benzyloctahydropyrrolo[3,4-b]pyrrole
Packaging
2g
Price
$209
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB143062
Product name
1-Benzyloctahydropyrrolo[3,4-b]pyrrole
Packaging
500mg
Price
$70
Updated
2021/12/16
Matrix Scientific
Product number
072082
Product name
1-Benzyloctahydropyrrolo[3,4-b]pyrrole
Purity
95+%
Packaging
1g
Price
$347
Updated
2021/12/16
More
Less

1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE Chemical Properties,Usage,Production

Uses

1-Benzyloctahydropyrrolo[3,4-b]pyrrole is used in the synthesis of intermediates as quinolone anti-bacterials.

Synthesis

132414-78-9

132414-50-7

General procedure for the synthesis of 1-benzyl octahydropyrrolo[3,4-B]pyrrole-5(1H)-carboxylic acid from ethyl 1-benzylhexahydropyrrolo[3,4-B]pyrrole: Ethyl 1-benzyl octahydropyrrolo[2,3-c]pyrrole-5-carboxylate (2.1 g, 7.65 mmol) was dissolved in 37% hydrochloric acid (11 mL), and the reaction was heated and refluxed for 24 hours. Upon completion of the reaction, the pH of the reaction solution was adjusted to 8 with sodium carbonate, followed by multiple extractions of the product with dichloromethane. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford 1.4 g of 1-benzyl octahydropyrrolo[3,4-B]pyrrole (90% yield) as a brown oil, which could be used for the next reaction without further purification. Mass spectral analysis (m/z): 203.2 [MH]+.

References

[1] Patent: WO2017/21920, 2017, A1. Location in patent: Paragraph 0633; 0634
[2] Patent: US5071999, 1991, A

1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE Suppliers

China 58 Germany 2 India 1 United Kingdom 1 United States 12 Global 74
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Carlow Chemicals Co., Ltd.
Tel
21-33526724 18930996265
Fax
37023730
Email
info@carlowchem.com
Country
China
ProdList
1922
Advantage
58
Shanghai ChuangYan Chemical Technology Co., Ltd.
Tel
021-11111111 11111111111
Fax
qq:546919421
Email
546919421@qq.com
Country
China
ProdList
3518
Advantage
55
Shanghai Tombiopharma Chemical Co. Ltd.
Tel
13391076197
Email
tombiopharma@163.com
Country
China
ProdList
4987
Advantage
55
Shanghai XR Chemical Technology Co., Ltd.
Tel
021-31007982 18019432809
Fax
021-31007982
Email
info@xrpharma.com
Country
China
ProdList
676
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Hangzhou Milestone Pharmtech Co., Ltd.
Tel
0571-82896630 18969958410
Email
sales_hz@milestonepharmtech.com
Country
China
ProdList
4894
Advantage
55
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12000
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
316
Advantage
55
Taizhou GreenChem Pharmaceutical Co., Ltd.
Tel
0514-86654616 15366892466
Email
greenchem@tzglmk.com
Country
China
ProdList
498
Advantage
56
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9021
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Adobe Chem Co., Ltd.
Tel
2332782371
Fax
QQ: 2332782371
Email
adobechem@qq.com
Country
China
ProdList
7980
Advantage
58
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
Sichuan BaiPeng Biotechnology Co., Ltd.
Tel
028-65791793 18140026355
Fax
QQ568470422
Email
568470422@qq.com
Country
China
ProdList
9997
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15083
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
4087
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Hefei Molake Biotechnology Co., Ltd.
Tel
0551-66336380 18956014586
Fax
055166336380
Email
983438788@qq.com
Country
China
ProdList
2297
Advantage
58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
Country
China
ProdList
19778
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Shanghai Songfan Pharmaceutical Technology Co., Ltd.
Tel
17321241880
Email
485229790@qq.com
Country
China
ProdList
1750
Advantage
58
Beijing xinyanhui pharmaceutical research and development co., LTD
Tel
13969155946
Email
1461866103@qq.com
Country
China
ProdList
16111
Advantage
58
Qi Qi hang Biotechnology Co., Ltd.
Tel
18151111370
Email
1046215251@qq.com
Country
China
ProdList
5999
Advantage
58
Zhengzhou anmousse chemical products co. LTD
Tel
0371-55289822 18737195735
Fax
QQ:483339295
Email
483339295@qq.com
Country
China
ProdList
7587
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Antai Fine Chemical Technology Co.,Limited
Tel
18503026267
Email
info@antaichem.com
Country
CHINA
ProdList
9636
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9947
Advantage
58
Wuhan YlypharmTech Co.,L
Tel
027-87212669 15927337358
Fax
027-87212669
Email
Sales@ylypharmtech.com
Country
China
ProdList
396
Advantage
58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15727060112
Email
yutianchun2007@126.com
Country
China
ProdList
9814
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
Shanghai Hanlin biology science and technology co., ltd
Tel
183-0212-4410 18302124410
Email
Djt18302124410@163.com
Country
China
ProdList
3000
Advantage
58
Hubei Co-prosperity Medicine Technonlogy Co., Ltd
Tel
2383948258 19172820304
Email
2383948258@qq.com
Country
China
ProdList
12987
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Tianjin shanhaijing medicine technology co., ltd
Tel
19129375004 15321929114
Email
yangtzechem@163.com
Country
China
ProdList
497
Advantage
58
Wuhan Brin Technology Co., Ltd.
Tel
3456065315 13260619011
Email
3456065315@qq.com
Country
China
ProdList
2192
Advantage
58
Heze Aiding Pharmaceutical Co., Ltd
Tel
17661365138
Email
2845578351@qq.com
Country
China
ProdList
7115
Advantage
58
Shanghai Haohong Scientific Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Taizhou GreenChem Pharma-Tech Co.,Ltd
Tel
15366892466
Email
greenchem@tzglmk.com
Country
China
ProdList
1028
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50751
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13795461237
Email
zhuruyan@jskchem.com
Country
China
ProdList
49234
Advantage
58
GIHI CHEMICALS CO.,LIMITED
Tel
+8618058761490
Email
info@gihichemicals.com
Country
China
ProdList
49941
Advantage
58
PT CHEM GROUP LIMITED
Tel
+86-85511178;
Email
peter68@ptchemgroup.com
Country
China
ProdList
35425
Advantage
58
More
Less

View Lastest Price from 1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE manufacturers

Career Henan Chemical Co
Product
1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE 132414-50-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-24

132414-50-7, 1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLERelated Search:

4-OXO-HEXAHYDRO-CYCLOPENTA[C]PYRROLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER TERT-BUTYL 1-OXO-2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLATE BICYCLO[2.2.2]OCTANE-1,4-DICARBOXYLIC ACID HEMIMETHYL ESTER Tert-butyl 1,7-diazaspiro[4,4]nonane-1-carboxylate Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate benzyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 2S-7-Aza-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid 7-tert-butyl ester 7-(TERT-BUTOXYCARBONYL)-1-OXA-2,7-DIAZASPIRO[4.4]NON-2-ENE-3-CARBOXYLIC ACID TERT-BUTYL 1-BENZYLHEXAHYDROPYRROLO[3,4-B]PYRROLE-5(1H)-CARBOXYLATE 1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE 2-Benzyl-Octahydro-Pyrrolo[3,4-C]Pyrrole HCl,2-BENZYL-OCTAHYDRO-PYRROLO [3,4-C] PYRROLE OCTAHYDRO-PYRROLO[3,4-B]PYRROLE 5-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRROLE DIHYDROCHLORIDE ETHYL 1-BENZYL-HEXAHYDROPYRROLO[3,4-B]PYRROLE-5(1H)-CARBOXYLATE 1-BENZYL-2-METHYLOCTAHYDROPYRROLO[3,4-B]PYRROLE 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRROLE HYDROCHLORIDE (3AS,6AS)-1-BENZYLOCTAHYDROPYRROLO[3,4-B]PYRROLE

  • 1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE
  • 1-Benzylhexahydropyrrolo[3,4-b]pyrrole
  • octahydro-1-(phenylmethyl)-Pyrrolo[3,4-b]pyrrole
  • 1-benzyl-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole
  • 1-(phenylmethyl)-3,3a,4,5,6,6a-hexahydro-2H-pyrrolo[2,3-c]pyrrole
  • Pyrrolo[3,4-b]pyrrole, octahydro-1-(phenylmethyl)-
  • 132414-50-7
  • Heterocycles series