4-(PYRIDIN-4-YL)ANILINE
- Product Name
- 4-(PYRIDIN-4-YL)ANILINE
- CAS No.
- 13296-04-3
- Chemical Name
- 4-(PYRIDIN-4-YL)ANILINE
- Synonyms
- 4-(Pyridin-4-yl);4-(4-Pyridyl)aniline;4-(4-Pyridinyl)aniline;4-(PYRIDIN-4-YL)ANILINE;4-(p-Aminophenyl)pyridine;4-(4-Aminophenyl)pyridine;4-PYRIDIN-4-YL-PHENYLAMINE;4-(4-Pyridinyl)benzenamine;4-(4-pyridinyl)benzeneaMine;4-(pyridin-4-yl)benzenaMine
- CBNumber
- CB7478471
- Molecular Formula
- C11H10N2
- Formula Weight
- 170.21
- MOL File
- 13296-04-3.mol
4-(PYRIDIN-4-YL)ANILINE Property
- Melting point:
- 232-234℃
- Boiling point:
- 319.1±17.0 °C(Predicted)
- Density
- 1.133
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 6.55±0.10(Predicted)
- Appearance
- Off-white to light brown Solid
- InChI
- InChI=1S/C11H10N2/c12-11-3-1-9(2-4-11)10-5-7-13-8-6-10/h1-8H,12H2
- InChIKey
- GKVYVZSNXXTOMQ-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(C2C=CN=CC=2)C=C1
Safety
- Hazard Codes
- Xi
- Risk Statements
- 20/21/22-36/37/38-38
- Safety Statements
- 26-36/37/39
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- P2782
- Product name
- 4-(Pyridin-4-yl)aniline
- Packaging
- 1G
- Price
- $160
- Updated
- 2025/07/31
- Product number
- P2782
- Product name
- 4-(Pyridin-4-yl)aniline
- Packaging
- 5G
- Price
- $568
- Updated
- 2025/07/31
- Product number
- P840665
- Product name
- 4-(4-Pyridinyl)aniline
- Packaging
- 2.5g
- Price
- $475
- Updated
- 2021/12/16
- Product number
- 074012
- Product name
- 4-(Pyridin-4-yl)aniline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $520
- Updated
- 2021/12/16
- Product number
- OR912614
- Product name
- 4-(Pyridin-4-yl)aniline
- Purity
- 95%
- Packaging
- 250mg
- Price
- $232
- Updated
- 2021/12/16
4-(PYRIDIN-4-YL)ANILINE Chemical Properties,Usage,Production
Uses
4-(4-Pyridinyl)aniline is diazotized, its product is nitrated and reduced to form 2-Amino-4-(4-pyridyl)phenol, which can increase cardiac contractility; Also, it is derived from 4-Pyridineboronic Acid (P991355), which is boronic acid derivative and their binding affinities with diols.
Synthesis
197435-52-2
13296-04-3
Tert-butyl 4-(pyridin-4-yl)phenylcarbamate (600 mg, 2.2 mmol) was treated with a mixture of dichloromethane (DCM) and trifluoroacetic acid (TFA) (1:1, 1 mL) for 2 hr at room temperature, and upon completion of the reaction, 4-(pyridin-4-yl)aniline (20) (380 mg, 99%) was obtained. Subsequently, the solvent was removed by distillation under reduced pressure. The structure of the product 4-(pyridin-4-yl)aniline (20) was 1H NMR (400 MHz, d6-DMSO) δ 8.81 (s, 2H), 8.25 (s, 2H), 7.76 (d, J = 8.7 Hz, 2H), 6.87 (m, 2H), 2.09 (s, 2H) and mass spectrometry (ESI) m/z 171 [M + H]+ for Confirmation. High resolution mass spectrometry (HRMS) calculated value of CnHn2 171.0917 and measured value of 171.0938 further verified the structure of the product.
References
[1] Journal of Medicinal Chemistry, 2012, vol. 55, # 5, p. 2474 - 2478
[2] Patent: WO2013/112722, 2013, A1. Location in patent: Page/Page column 45
[3] Dyes and Pigments, 2017, vol. 137, p. 229 - 235
[4] Journal of Medicinal Chemistry, 1997, vol. 40, # 22, p. 3542 - 3550
4-(PYRIDIN-4-YL)ANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(PYRIDIN-4-YL)ANILINE manufacturers
- Product
- 4-(PYRIDIN-4-YL)ANILINE 13296-04-3
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2018-12-24