4-Ethynylbenzonitrile

Product Name: 4-Ethynylbenzonitrile
CAS No.: 3032-92-6
Chemical Name: 4-Ethynylbenzonitrile
Synonyms: (4-Cyanophenyl)ethyne;4-Cyanophenylacetylene;1-Cyano-4-ethynylbenzene;Benzonitrile, 4-ethynyl-;4-ETHYNYLBENZONITRILE 97;4-Ethynylbenzonitrile 97%;Benzonitrile, 4-ethynyl- (9CI)
CBNumber: CB7498992
Molecular Formula: C9H5N
Formula Weight: 127.14
MOL File: 3032-92-6.mol

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4-Ethynylbenzonitrile Property

Melting point:: 156-160 °C(lit.)
Boiling point:: 230.2±23.0 °C(Predicted)
Density: 1.037 g/mL at 25 °C(lit.)
Flash point:: >110 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Solid
color: Pale yellow
Water Solubility: Slightly soluble in water.

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 206539
Product name: 4-Ethynylbenzonitrile
Purity: 97%
Packaging: 5g
Price: $256.2
Updated: 2025/07/31

TCI Chemical

Product number: E0872
Product name: 4-Ethynylbenzonitrile
Purity: min. 97.0 %
Packaging: 1G
Price: $71
Updated: 2025/07/31

TCI Chemical

Product number: E0872
Product name: 4-Ethynylbenzonitrile
Purity: min. 97.0 %
Packaging: 5G
Price: $213
Updated: 2025/07/31

TRC

Product number: E932163
Product name: 4-Ethynylbenzonitrile
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: E932163
Product name: 4-Ethynylbenzonitrile
Packaging: 500mg
Price: $65
Updated: 2021/12/16

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4-Ethynylbenzonitrile Chemical Properties,Usage,Production

Uses

4-Ethynylbenzonitrile is used as a synthetic fragment and as a test compound for cross-coupling reactions. It is used in the study of hydrogen bond formation in multifunctional molecules due to the presence of four hydrogen bonding sites. It is also involved in the preparation of 4-[(trimethylsilyl)ethynyl]benzonitrile.

General Description

The water complexes formed with 4-ethynylbenzonitrile (4EBzN) were studied using IR-UV double resonance spectroscopy.

Synthesis

75867-40-2

3032-92-6

General procedure for the synthesis of 4-ethynylbenzonitrile from 4-[(trimethylsilyl)ethynyl]benzyl cyanide: potassium carbonate (50 mg, 0.36 mmol) was added to a mixed methanol/tetrahydrofuran solution (16 mL, 1:1) of 4-[(trimethylsilyl)ethynyl]benzyl cyanide (1.1 g, 5.3 mmol). The reaction mixture was stirred at room temperature for 30 min, followed by removal of the solvent by rotary evaporator. The residue was diluted with ethyl acetate and washed sequentially with 10% aqueous hydrochloric acid and saturated saline. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 4-ethynylbenzonitrile as a white solid (0.61 g, 4.80 mmol, 91% yield).

References

[1] Tetrahedron, 2003, vol. 59, # 3, p. 287 - 293
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 21, p. 4036 - 4052
[3] Journal of the American Chemical Society, 1997, vol. 119, # 43, p. 10401 - 10412
[4] Journal of Organic Chemistry, 2014, vol. 79, # 16, p. 7342 - 7357
[5] New Journal of Chemistry, 2017, vol. 41, # 6, p. 2296 - 2308

4-Ethynylbenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Ethynylbenzonitrile Suppliers

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View Lastest Price from 4-Ethynylbenzonitrile manufacturers

Shanghai UCHEM Inc.

Product: 4-Ethynylbenzonitrile 3032-92-6
Price: US $25.00-407.00/g
Min. Order: 5g
Purity: 0.97
Supply Ability: 10kg
Release date: 2023-12-04

Career Henan Chemical Co

Product: 4-ETHYNYLBENZONITRILE 97 3032-92-6
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

3032-92-6, 4-EthynylbenzonitrileRelated Search:

2-Amino-5-(1-methylethyl)benzonitrile 3-Ethylbenzonitrile (R)-3-(1-aminoethyl)benzonitrile 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile 4-CYANOPHENYLETHYLAMINE HCL 4-Ethylbenzonitrile (S)-3-(1-Aminoethyl)benzonitrile 4-Ethynylbenzonitrile 4-(3-HYDROXY-PROP-1-YNYL)-BENZONITRILE 4-(2-PHENYLETH-1-YNYL)BENZONITRILE 4-(4-METHOXY-PHENYLETHYNYL)-BENZONITRILE 4-(3-HYDROXY-1-BUTYNYL)BENZONITRILE 4-(3-HYDROXY-3-METHYL-1-BUTYNYL)BENZONITRILE 4-(2'-TRIMETHYLSILYLETHYNYL)BENZONITRILE 4-O-TOLYLETHYNYL-BENZONITRILE 4-HEX-1-YNYLBENZONITRILE 4-(2-BROMO-PHENYLETHYNYL)-BENZONITRILE 4-(3-METHOXY-PHENYLETHYNYL)-BENZONITRILE

4-Cyanophenylacetylene

(4-Cyanophenyl)ethyne

1-Cyano-4-ethynylbenzene

4-Ethynylbenzonitrile 97%

4-ETHYNYLBENZONITRILE 97

Benzonitrile, 4-ethynyl- (9CI)

Benzonitrile, 4-ethynyl-

3032-92-6

HC8801CC6H4CN

HCCC6H4CN

C9H5N

C8 to C9

Cyanides/Nitriles

Nitrogen Compounds