DITHIO-BIS-MALEIMIDOETHANE

Product Name: DITHIO-BIS-MALEIMIDOETHANE
CAS No.: 71865-37-7
Chemical Name: DITHIO-BIS-MALEIMIDOETHANE
Synonyms: CAS_71865-37-7;Bis(2-maleimidoethyl) Disulfide;DTME (dithio-bis-maleimid&œ1,1'-(Dithiodi-2,1-ethanediyl)bis-1H-pyrrole-2,5-dione;1,1'-(Disulfanediylbis(ethane-2,1-diyl))bis(1H-pyrrole-2,5-dione);1,1'-[Disulfanediylbis(ethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione);1-[2-[2-(2,5-dioxopyrrol-1-yl)ethyldisulfanyl]ethyl]pyrrole-2,5-dione;1-[2-[[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]dithio]ethyl]-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-[2-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]dithio]ethyl]-
CBNumber: CB7506718
Molecular Formula: C12H12N2O4S2
Formula Weight: 312.36
MOL File: 71865-37-7.mol

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DITHIO-BIS-MALEIMIDOETHANE Property

Melting point:: 124°C
Boiling point:: 518.6±35.0 °C(Predicted)
Density: 1.511±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly)
pka: -2.05±0.20(Predicted)
form: powder to crystal
color: White to Light yellow
Stability:: Temperature Sensitve, Moisture Sensitive
InChI: 1S/C12H12N2O4S2/c15-9-1-2-10(16)13(9)5-7-19-20-8-6-14-11(17)3-4-12(14)18/h1-4H,5-8H2
InChIKey: SGVWDRVQIYUSRA-UHFFFAOYSA-N
SMILES: O=C(C=CC1=O)N1CCSSCCN2C(C=CC2=O)=O

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Safety

WGK Germany: WGK 3
HS Code: 2930.90.9250
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 803618
Product name: DTME (dithio-bis-maleimidoethane)
Packaging: 50MG
Price: $482
Updated: 2023/06/20

TCI Chemical

Product number: B5699
Product name: Bis(2-maleimidoethyl) Disulfide
Purity: >98.0%(HPLC)(N)
Packaging: 25mg
Price: $156
Updated: 2026/03/19

TCI Chemical

Product number: B5699
Product name: Bis(2-maleimidoethyl) Disulfide
Purity: >98.0%(HPLC)(N)
Packaging: 100mg
Price: $466
Updated: 2026/03/19

TRC

Product number: D494300
Product name: Dithio-bis-maleimidoethane
Packaging: 10mg
Price: $175
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD22563
Product name: Dithio-bis-maleimidoethane
Packaging: 10mg
Price: $199.9
Updated: 2021/12/16

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DITHIO-BIS-MALEIMIDOETHANE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A sulfhydryl reactive homobifunctional crosslinking reagent. Spacer Arm: 13.3 Angstroms

Uses

A sulfhydryl reactive homobifunctional crosslinking reagent.Spacer Arm: 13.3 Angstroms

General Description

DTME is a homobifunctional, maleimide crosslinker for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e., oligomerization) or protein interactions. DTME is similar in length to BMH but differs in containing a disulfide bond in its spacer arm, allowing crosslinks with DTME to be cleaved with reducing agent such as dithiothreitol (DTT).

reaction suitability

reagent type: cross-linking reagent

DITHIO-BIS-MALEIMIDOETHANE Preparation Products And Raw materials

Raw materials

Preparation Products

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DITHIO-BIS-MALEIMIDOETHANE Suppliers

Americas 1 Canada 1 China 42 Europe 1 India 1 Japan 1 United Kingdom 1 United States 3 Global 51

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Sigma-Aldrich

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71865-37-7, DITHIO-BIS-MALEIMIDOETHANERelated Search:

N,N'-BIS(ACRYLOYL)CYSTAMINE DITHIO-BIS-MALEIMIDOETHANE N-Ethylmaleimide 1,4-BIS-MALEIMIDOBUTANE GMBS N-SUCCINIMIDYL 6-(3-MALEIMIDOPROPIONAMIDO) HEXANOATE SMCC crosslinker 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester) 1,8-BIS-MALEIMIDOTRIETHYLENEGLYCOL

1,1'-(Dithiodi-2,1-ethanediyl)bis-1H-pyrrole-2,5-dione

1-[2-[[2-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]dithio]ethyl]-1H-pyrrole-2,5-dione

Bis(2-maleimidoethyl) Disulfide

CAS_71865-37-7

1H-Pyrrole-2,5-dione, 1-[2-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]dithio]ethyl]-

1-[2-[2-(2,5-dioxopyrrol-1-yl)ethyldisulfanyl]ethyl]pyrrole-2,5-dione

1,1'-[Disulfanediylbis(ethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione)

DTME (dithio-bis-maleimid&&oelig

1,1'-(Disulfanediylbis(ethane-2,1-diyl))bis(1H-pyrrole-2,5-dione)

71865-37-7

Maleimide Derivatives

Cross Linking Reagents

MTS & Sulfhydryl Active Reagents