ChemicalBook > CAS DataBase List > 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
- Product Name
- 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
- CAS No.
- 143030-02-8
- Chemical Name
- 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
- Synonyms
- Rapamycin Impurity 32;42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin;Rapamycin, 42-O-[(1,1-dimethylethyl)dimethylsilyl]-;Clobetasone Butyrate Impurity 9 (Clobetasone Butyrate EP Impurity I)
- CBNumber
- CB75177306
- Molecular Formula
- C57H93NO13Si
- Formula Weight
- 1028.45
- MOL File
- 143030-02-8.mol
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42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Property
- Boiling point:
- 977.0±75.0 °C(Predicted)
- Density
- 1.12±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Dichloromethane, Methanol
- form
- Solid
- pka
- 10.40±0.70(Predicted)
- color
- White
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N-Bromosuccinimide Price
TRC
- Product number
- D479400
- Product name
- 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
- Packaging
- 25mg
- Price
- $735
- Updated
- 2021/12/16
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42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Chemical Properties,Usage,Production
Uses
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin is an intermediate in the synthesis of 8-O-Methyl-rapamycin which is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Preparation Products And Raw materials
Raw materials
Preparation Products
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143030-02-8, 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycinRelated Search:
Everolimus
2-Piperidinecarboxylic acid, 1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-, (1S,4R,5E)-1-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-4,6-dimethyl-3,7-dioxo-5-heptenyl es...
Everolimus EP Impurity E
USDOYNAPNXMXOE-SPSCNLKESA-N
Everolimus Impurity 1
23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexam...
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EveroliMus-d4
Everolimus Related Compound 2
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Seco Rapamycin
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28-epirapamycin
Everolimus Ring-Opening Impurity
2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone