HALOPERIDOL DECANOATE Property

Melting point:

42-44°C

storage temp. 

Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Solid

color 

White

Hazard and Precautionary Statements (GHS)

HALOPERIDOL DECANOATE Chemical Properties,Usage,Production

Uses

Antipsychotic.

brand name

Haldol (Ortho-McNeil).

General Description

Haloperidol decanoate, 4-[4-(4-chlorophenyl)-4-hydroxypiperidino]-4-fluorobutyrophenonedecanoate (Haldol Decanoate), is the decanoate ester(prodrug) of haloperidol. Peak plasma concentrations occurwithin 3 to 9 days and then decrease slowly. Haloperidol decanoatehas no intrinsic activity. Haloperidol decanoate undergoes hydrolysis by plasma and/or tissue esterases toform haloperidol and decanoic acid, subsequently; haloperidolis metabolized in the liver. The pharmacological effectsare those of haloperidol, which is released by bioconversion.Haloperidol decanoate is indicated for the treatment of longtermmaintenance in schizophrenia, psychoses especiallyparanoid, and other mental and behavioral problems.