RICTOR antibody

Source Reactivity Background References

Product Name: RICTOR antibody
Chemical Name: RICTOR antibody
Synonyms: RICTOR antibody
CBNumber: CB75692685
Formula Weight: 0
MOL File: Mol file

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

RICTOR antibody Chemical Properties,Usage,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Monkey

Background

Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian TOR pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals. mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GβL and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GβL, Sin1, and rictor. The mTOR-rictor complex phosphorylates Ser473 of Akt/PKB in vitro. This phosphorylation is essential for full Akt/PKB activation. Furthermore, an siRNA knockdown of rictor inhibits Ser473 phosphorylation in 3T3-L1 adipocytes. This complex has also been shown to phosphorylate the rapamycin-resistant mutants of S6K1, another effector of mTOR.

References

[1] Sarbassov, D.D. et al. (2004) Curr. Biol. 14, 1296-1302.
[2] Sarbassov, D.D. et al. (2005) Science 307, 1098-1101.
[3] Hresko, R.C. and Mueckler, M. (2005) J. Biol. Chem. 280, 40406-40416.
[4] Ali, S.M. and Sabatini, D.M. (2005) J. Biol. Chem. 280, 19445-19448.

RICTOR antibody Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

RICTOR antibody Suppliers

China 75 Global 75

Shanghai Universal Biotech Co.,Ltd

Tel: 15921930842 15921930842
Email: yh-wang@univ-bio.com
Country: China
ProdList: 25004
Advantage: 58

Hubei ipodix Biotech Technology Co., Ltd

Tel: 18007124176
Email: ipdshengwu@163.com
Country: China
ProdList: 4801
Advantage: 58

Hubei Ipodix Biotechnology Co.,Ltd.

Tel: 18007124176 19384116026
Email: 2706668885@qq.com
Country: China
ProdList: 4987
Advantage: 58

Novus Biologicals

Tel: 400821347
Email: orders@novusbio.com
Country: China
ProdList: 6433
Advantage: 58

CUSABIO TECHNOLOGY LLC

Tel: 027-87196173
Email: cusabio@163.com
Country: China
ProdList: 6066
Advantage: 58

NSJ Bioreagents

Tel: 858.663.9055 8586639055
Email: NSJBioname@qq.com
Country: China
ProdList: 6941
Advantage: 58

Enzo Biochem Inc

Tel: Enzo Biochem Inc. 13797054060
Email: Enzoname@qq.com
Country: China
ProdList: 6174
Advantage: 58

Biosynth Ltd

Tel: 18886812933
Email: sales@biosynth.com
Country: China
ProdList: 6218
Advantage: 58

Cell Signaling Technology Inc

Tel: 21-80243558 86218024
Email: info@cellsignal.cn
Country: China
ProdList: 6725
Advantage: 58

Abmart Inc

Tel: 4006-123-828 13162017139
Email: market@ab-mart.com
Country: China
ProdList: 6917
Advantage: 58

RICTOR antibodyRelated Search:

ATP2C1 antibody DIRAS3 antibody APTX antibody AGBL2 antibody PRKAA2 Antibody CDC37L1 Antibody GAB1 antibody CAMK4 antibody FASTKD2 antibody FANCG antibody

RICTOR antibody