N-(Trimethylsilyl)acetamide

Product Name: N-(Trimethylsilyl)acetamide
CAS No.: 13435-12-6
Chemical Name: N-(Trimethylsilyl)acetamide
Synonyms: TMSA;DK063;TMS ACETAMIDE;trimethylsilyl;N-TMS-acetamide;N-(Trimethylsilyl);TRIMETHYLSILYLACETAMIDE;N-TRIMETHYLSILYLACETAMIDE;n-(trimethylsilyl)-acetamid;(acetylamino)trimethylsilane
CBNumber: CB7667530
Molecular Formula: C5H13NOSi
Formula Weight: 131.25
MOL File: 13435-12-6.mol

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N-(Trimethylsilyl)acetamide Property

Melting point:: 46-49 °C(lit.)
Boiling point:: 84 °C18 mm Hg(lit.)
Density: 0.859±0.06 g/cm3(Predicted)
Flash point:: 135 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform, DMSO, Methanol
form: Crystalline Mass
pka: 18.23±0.46(Predicted)
color: White to yellow
Water Solubility: reacts
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
Sensitive: Moisture Sensitive
BRN: 741928
Stability:: Moisture Sensitive
CAS DataBase Reference: 13435-12-6(CAS DataBase Reference)
EPA Substance Registry System: Acetamide, N-(trimethylsilyl)- (13435-12-6)

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Safety

Hazard Codes: Xi-F,Xi,F
Risk Statements: 36/37/38-11
Safety Statements: 37/39-26
RIDADR: 1325
WGK Germany: 3
RTECS: AD0250000
F: 10-21
TSCA: Yes
HazardClass: 4.1
PackingGroup: III
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 223298
Product name: N-(Trimethylsilyl)acetamide
Purity: 95%
Packaging: 25g
Price: $124
Updated: 2024/03/01

TCI Chemical

Product number: T0590
Product name: N-Trimethylsilylacetamide
Purity: >98.0%(GC)
Packaging: 25g
Price: $118
Updated: 2024/03/01

TRC

Product number: T796720
Product name: N-Trimethylsilylacetamide
Packaging: 25g
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 468234
Product name: Trimethylsilyl
Packaging: 10g
Price: $319
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 42527
Product name: N-Trimethylsilylacetamide
Packaging: 50g
Price: $640
Updated: 2021/12/16

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N-(Trimethylsilyl)acetamide Chemical Properties,Usage,Production

Chemical Properties

WHITE TO YELLOWISH CRYSTALLINE MASS

Uses

N-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).

General Description

The efficiency of N-(Trimethylsilyl)acetamide (TMS acetamide) as allyl group scavenger and its compatibility with Fluorenylmethyloxycarbonyl chloride (Fmoc) protecting groups were studied.

Purification Methods

Distil the amide repeatedly in an inert atmosphere with all operations to be performed in an anhydrous atmosphere. In the presence of moisture, trimethylsilanol (b 31-34o/26mm) is formed and is a likely impurity (check by NMR). [Birkofer et al. Chem Ber 96 1473 1963, Beilstein 4 IV 4011.]

N-(Trimethylsilyl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

Cefdinir

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N-(Trimethylsilyl)acetamide Suppliers

Belgium 3 Canada 1 China 119 Europe 2 Germany 7 India 4 Italy 1 Japan 4 Singapore 1 Switzerland 2 United Kingdom 7 United States 34 Global 185

NBS Biologicals

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CARBONE SCIENTIFIC CO.,LTD

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MOLEKULA Ltd.

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Fluorochem Ltd.

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VWR International

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View Lastest Price from N-(Trimethylsilyl)acetamide manufacturers

Hubei Changfu Chemical Co., Ltd.

Product: N-Trimethylsilylacetamide 13435-12-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 97%
Supply Ability: 20t
Release date: 2024-04-26

Zhengzhou Gecko Scientific Inc.

Product: N-(Trimethylsilyl)acetamide 13435-12-6
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 100%
Supply Ability: 10kg
Release date: 2022-09-27

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-(Trimethylsilyl)acetamide 13435-12-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

13435-12-6, N-(Trimethylsilyl)acetamideRelated Search:

N,N-Dimethylacetamide Acetamide Trimethylsilylacetylene Acetaminophen 1-TRIMETHYLSILYL-2-PYRROLIDINONE N,O-Bis(trimethylsilyl)acetamide Silicone rubber,methyl-vinyl N-(tert-Butyldimethylsilyl)-N-methyl-trifluoroacetamide BIS(TRIMETHYLSILYL)HYPOXATHINE N-METHYL-N-TRIMETHYLSILYLHEPTAFLUOROBUTYRAMIDE N-Methyl-N-(trimethylsilyl)acetamide N-Methyl-N-(trimethylsilyl)trifluoroacetamide N-(TERT-BUTYLDIMETHYLSILYL)PHTHALIMIDE N,N-Bis(trimethylsilyl)acetamide (4S)-N-(TERT-BUTYLDIMETHYLSILYL)AZETIDIN-2-ONE-4-CARBOXYLIC ACID (4R)-N-(TERT-BUTYLDIMETHYLSILYL)AZETIDIN-2-ONE-4-CARBOXYLIC ACID (5-METHYL-1,3-BIS-TRIMETHYLSILYL)-2,4-(1H,3H-PYRIMIDINEDIONE) METHACRYLAMIDOTRIMETHYLSILANE

N-(TRIMETHYLSILYL)ACETAMIDE FOR SYNTHESI

N-(Trimethylsilyl)acetamide,97%

N-(Trimethylsilyl)

(acetylamino)trimethylsilane

n-(trimethylsilyl)-acetamid

N-TRIMETHYLSILYLACETAMIDE

TRIMETHYLSILYLACETAMIDE

TMSA

TMS ACETAMIDE

N-TrimethylsilylacetamideA.R.

trimethylsilyl

N-TRIMETHYLSILYL ACETAMIDE(TMSA)

N-TMS-acetamide

Acetamide, N-(trimethylsilyl)-

N-Trimethylsilylacetamide &gt

13435-12-6 N-(Trimethylsilyl)acetamide

DK063

13435-12-6

C5H13NOSi

CH3CONHSiCH33

Derivatization Reagents

Fluka Reagents

Organic Building Blocks

Si (Classes of Silicon Compounds)

Silylation (GC Derivatizing Reagents)

Silylacetamides

Acyclic

Alkenes

Analytical Chromatography Product Catalog

Building Blocks

Trimethylsilylation (GC Derivatizing Reagents)

Si-N Compounds

GC Derivatizing Reagents

Silicon Compounds (for Synthesis)

Aliphatics

Miscellaneous Reagents

Analytical Chemistry

GC Derivatizing Reagents

Si (Classes of Silicon Compounds)

Silicon Compounds (for Synthesis)

Silylacetamides

Silylation (GC Derivatizing Reagents)

Si-N Compounds

Synthetic Organic Chemistry

Trimethylsilylation (GC Derivatizing Reagents)