Description
ChemicalBook > CAS DataBase List > Ethylenebis(oxyethylenenitrilo)tetraacetic acid

Ethylenebis(oxyethylenenitrilo)tetraacetic acid

Description
Product Name
Ethylenebis(oxyethylenenitrilo)tetraacetic acid
CAS No.
67-42-5
Chemical Name
Ethylenebis(oxyethylenenitrilo)tetraacetic acid
Synonyms
EGTA;EGTAZIC ACID;1,2-bis(2-dicarboxymethylaminoethoxy)ethane;ethylenedioxybis(ethyleneamino)tetraaceticacid;AEGT;GEDTA;GIETA;ebonta;Egtazic;CHEL-DE
CBNumber
CB7671001
Molecular Formula
C14H24N2O10
Formula Weight
380.35
MOL File
67-42-5.mol
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Ethylenebis(oxyethylenenitrilo)tetraacetic acid Property

Melting point:
241 °C (dec.)(lit.)
Boiling point:
507.99°C (rough estimate)
Density 
1.2838 (rough estimate)
bulk density
450kg/m3
refractive index 
1.4590 (estimate)
storage temp. 
room temp
solubility 
0.1 M NaOH: 0.1 M at 20 °C, clear, colorless
form 
Crystalline Powder
pka
1.47±0.10(Predicted)
color 
White
biological source
synthetic (organic)
Water Solubility 
slightly soluble
Merck 
14,3529
BRN 
1717370
CAS DataBase Reference
67-42-5(CAS DataBase Reference)
EPA Substance Registry System
Ethylenebis(oxyethylenenitrilo)tetraacetic acid (67-42-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
2
RTECS 
AH3760000
TSCA 
Yes
HS Code 
29225000
Toxicity
LD50 orally in Rabbit: 3587 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
4100-OP
Product name
OmniPur EGTA -CAS 67-42-5 - Calbiochem
Packaging
50g
Price
$240
Updated
2024/03/01
Sigma-Aldrich
Product number
1.08435
Product name
Titriplex® VI
Purity
for analysis
Packaging
25g
Price
$431
Updated
2024/03/01
Sigma-Aldrich
Product number
324626
Product name
EGTA, Molecular Biology Grade - CAS 67-42-5 - Calbiochem
Packaging
25g
Price
$185
Updated
2024/03/01
Sigma-Aldrich
Product number
1.08435
Product name
Titriplex® VI
Purity
for analysis
Packaging
100g
Price
$631
Updated
2024/03/01
Sigma-Aldrich
Product number
1.08435
Product name
Titriplex® VI
Purity
for analysis
Packaging
1kg
Price
$4210
Updated
2024/03/01
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Ethylenebis(oxyethylenenitrilo)tetraacetic acid Chemical Properties,Usage,Production

Description

Ethylenebis(oxyethylenenitrilo)tetraacetic acid is also named as Egtazic acid. It works as a chelating agent for the determination of calcium in the presence of magnesium.

Chemical Properties

White to slightly off-white powder

Uses

Pharmaceutic aid. EGTA.

Uses

Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid is a chelating agent used for making complexes, especially for calcium ions, which help to determine calcium in the presence of magnesium. It can be used experimentally for treating animals possessing cerium poisoning. It is useful in the separation of thorium from monazite. It also acts as a buffer and is used in protein purification.

Uses

A chelating agent useful for the determination of calcium in the presence of magnesium.

Definition

ChEBI: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.

reaction suitability

reagent type: chelator

Biological Activity

Calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.

Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx. See also GLYCOL ETHERS.

storage

Room temperature

Purification Methods

Dissolve EGTA in aqueous NaOH, precipitate it by adding aqueous HCl, wash it with water and dry at 100o in vacuo.[Beilstein 4 IV 217.]

Ethylenebis(oxyethylenenitrilo)tetraacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ethylenebis(oxyethylenenitrilo)tetraacetic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Ethylenebis(oxyethylenenitrilo)tetraacetic acid EGTA 67-42-5
Price
US $99.00-35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-17
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ethylenebis(oxyethylenenitrilo)tetraacetic acid 67-42-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
3500kg/month
Release date
2021-09-11
Baoji Guokang Bio-Technology Co., Ltd.
Product
Ethylenebis(oxyethylenenitrilo)tetraacetic acid 67-42-5
Price
US $198.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1-800kg
Release date
2021-06-08

67-42-5, Ethylenebis(oxyethylenenitrilo)tetraacetic acidRelated Search:

ETHYLENE Ethyl ethoxyacetate Iminodiacetic acid Ethylene glycol 2-Butoxyethanol 2-Phenoxyethanol 2-Butoxyethyl acetate Ethylene carbonate Folic acid Ethyl 2-(Chlorosulfonyl)acetate Citric acid GLYCOFUROL POLY(ETHYLENE-CO-ACRYLIC ACID) Ethylenediamine-N,N'-diacetic acid Hyaluronic acid Stearic acid 2-(Vinyloxy)ethanol ETHANE

  • 3,6-DIOXAOCTAMETHYLENEDINITRILOTETRAACETIC ACID
  • 1,2-bis(2-dicarboxymethylaminoethoxy)ethane
  • 12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-9-dioxa-3
  • 6,9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-
  • 9-Dioxa-3,12-diazatetradecanedioicacid,3,12-bis(carboxymethyl)-6
  • ebonta
  • ethylenedioxybis(ethyleneamino)tetraaceticacid
  • ETHYLENE GLYCOL BIS-(BETA-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC
  • Egtazic
  • chel tm -de
  • ETHYLENE GLYCOL-BIS(B-AMINOETHYL*ETHER)N ,N,N',N'-TE
  • ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHYL)-N ,N,N',N'-T.ACET.AC
  • ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHYL)-N ,N,N',N'-TETRAAC.
  • IDRANAL VI R. G.
  • ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHYL)-N ,N,N',N'-TETRAACET.
  • EGTA MOLECULAR BIOLOGY REAGENT
  • Egta(EthyleneGlycolBis-(AminoethylEther)TetraceticAcid)
  • 1,2-Bis-(2-aminoethoxyethane)-N,N,N',N'-tetraaceti
  • ETHYLENEGLYCOL-bis-(AMINOETHYLETHER)-TETRAACETIC ACID REAGENT (EGTA)
  • ETHYLENE GLYCOL-O,-O'-bis(2-AMINOETHYL) N,N,N,N-TETRAACETIC ACID extrapure
  • ChelTM-DE, EGTA, Egtazic acid, Ethylene-bis(oxyethylenenitrilo)tetraacetic acid, Glycol ether diamine tetraacetic acid
  • ETHYLENEGLYCOLBIS(2-AMINOETHYLETHER)-N,N,NNTETRAACETICACID,HIGHPURITY
  • ETHYLENEGLYCOLBIS(BETA-AMINOETHYLETHER)TETRAACETICACID
  • ETHYLENE GLYCOL-O,O''-BIS(2-AMINOSTHYL)-N,N,N'',N''-TETRAACETIC ACID
  • ETHYLENE GLYCOL BIS(2-AMINOETHYL ETHER)TETRAACETIC ACID (EGTA)
  • EGTA MOLECULAR BIOLOGY GRADE
  • ETHYLENEGLYCOL-BIS(2-AMINOETHYLETHER)-N,N,N'',N''-TETRAACETICACID(EGTA)
  • Ethylene glycol-bis(b-aminoethyl ether)-N,N,N'',N''-tetraacetic acid
  • 3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetra-decane-1,14-dioic acid (EGTA)
  • EGTA (Ethyleneglycol bis (2-AMinoethyl ether)-N,N,N',N' Tetraacetic acid
  • BROMOMETHANE 200UG/ML IN METHANOL
  • EGTA, egtazic acid
  • VENTING SCREW CAP (CLOCK) PP RED DIN 45
  • Ethylene Glycol Bis(β-aminoethylether)-N,N,N',N'-tetraacetic Acid 〔EGTA
  • 2-Di(2-aminoethoxy)ethane-N,N,N,N-tetraacetic acid
  • ETHYLENE GLYCOL-BIS(2-AMINOETHYLETHE
  • ETHYLENE GLYCOL-BIS(B-AMINOETHYL*ETH
  • ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHY
  • Ethylenebis(oxyethylenenitrilo)
  • Ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetraacetic acid≥ 99% (Titration)
  • Titriplex VI for analysis
  • Ethylene glycol-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, 99% EGTA
  • EGTA bio grade 99%
  • EGTA, egtazic acid, Glycol ether diamine tetraacetic acid
  • 1,2-DI(2-AMINOETHOXY)ETHANE-NNN'N'-TETRA-ACETIC ACID
  • 1,2-BIS[2-[BIS(CARBOXYMETHYL)AMINO]ETHOXY]ETHANE
  • 2,2'-ETHYLENEDIOXYBIS[ETHYLIMINODI(ACETIC ACID)]
  • GLYCOLETHERDIAMINE-N,N,N',N'-TETRAACETIC ACID
  • GLYCOL ETHER DIAMINE TETRAACETIC ACID
  • IDRANAL(R) VI
  • GEDTA
  • ETHYLENE-BIS(OXYETHYLENENITRILLO)TETRAACETIC ACID
  • ETHYLENEBIS(OXYETHYLENENITRILO)TETRAACETIC ACID
  • ETHYLENE GLYCOL-O,O'-BIS(2-AMINOETHYL)-N,N,N',N'-TETRAACETIC ACID
  • ETHYLENEDIOXYBIS(ETHYLAMINE)-N,N,N',N'-TETRAACETIC ACID
  • ETHYLENEDIOXYBIS(ETHYLENENITRILO)-TETRAACETIC ACID
  • ETHYLENE GLYCOL-BIS(2-AMINOETHYLETHER)-N,N,N',N'-TETRAACETIC ACID
  • ETHYLENE GLYCOL BIS[2-AMINOETHYL ETHER]TETRAACETIC ACID