5-Bromotryptophol
- Product Name
- 5-Bromotryptophol
- CAS No.
- 32774-29-1
- Chemical Name
- 5-Bromotryptophol
- Synonyms
- 2-(5-broMo-1H-indol-3-yl)ethan-1-ol;5-bromochromol;5-BROMOTRYPTOPHOL;L806 5-Bromotryptophol;5-Bromoindole-3-ethanol;5-bromo-1H-indole-3-ethanol;2-(5-Bromo-3-indolyl)ethanol;1H-Indole-3-ethanol, 5-bromo-;5-Bromo-3-(2-hydroxyethyl)indole;2-(5-Bromo-1H-indol-3-yl)ethanol
- CBNumber
- CB7671713
- Molecular Formula
- C10H10BrNO
- Formula Weight
- 240.1
- MOL File
- 32774-29-1.mol
5-Bromotryptophol Property
- Melting point:
- 92-94°C
- Boiling point:
- 411.5±30.0 °C(Predicted)
- Density
- 1.618±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder to crystal
- pka
- 14.87±0.10(Predicted)
- color
- White to Orange to Green
- CAS DataBase Reference
- 32774-29-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B5068
- Product name
- 5-Bromoindole-3-ethanol
- Purity
- >98.0%(GC)
- Packaging
- 200mg
- Price
- $66
- Updated
- 2025/07/31
- Product number
- B5068
- Product name
- 5-Bromoindole-3-ethanol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $198
- Updated
- 2025/07/31
- Product number
- B686398
- Product name
- 2-(5-Bromo-1H-indol-3-yl)ethanol
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB144419
- Product name
- 2-(5-Bromo-1H-indol-3-yl)ethanol
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 44516
- Product name
- 5-Bromoindole-3-ethanol,≥98%(GC)
- Purity
- ≥98%(GC)
- Packaging
- 250MG
- Price
- $112.57
- Updated
- 2021/12/16
5-Bromotryptophol Chemical Properties,Usage,Production
Synthesis
117235-22-0
32774-29-1
General procedure for the synthesis of 2-(5-bromo-1H-indol-3-yl)ethanol from methyl (5-bromo-1H-indol-3-yl)-acetate: to a solution of methyl ester (5-bromo-1H-indol-3-yl)-acetate (4 mmol, 1 eq.) in anhydrous THF (50 mL) was added lithium aluminum hydride (LiAlH4; 16 mmol, 4 eq.) in batches and the reaction The temperature was maintained at 0 °C. The reaction mixture was gradually brought to room temperature with continuous stirring for 30 min. The excess LiAlH4 was quenched by slow addition of saturated aqueous Na2SO4 while maintaining the temperature at about 0 °C. The reaction mixture was filtered. The reaction mixture was filtered and the filtrate was washed with THF. After combining the filtrates, the solvent was removed by concentration under reduced pressure and the residue was adjusted to pH 6 with 10% HCl solution and subsequently extracted with CHCl3. The organic layers were combined, dried with anhydrous Na2SO4, filtered and evaporated to dryness. The crude product was purified by fast column chromatography using EtOAc/hexane as eluent to afford the target product 2-(5-bromo-1H-indol-3-yl)ethanol. Yield: 83%; 1H NMR (300 MHz, CDCl3): δ 2.97 (t, J = 18 Hz, 2H), 3.86-3.93 (m, 2H), 4.09 (t, J = 21 Hz, 1H), 7.09 (d, J = 3 Hz, 1H), 7.22 (d, J = 9 Hz, 1H), 7.75 (s, 1H), 8.10 ( s, 1H); MS (APCI): m/z 241.2 [M + H]+.
References
[1] Journal of Medicinal Chemistry, 2010, vol. 53, # 19, p. 6838 - 6850
[2] Patent: WO2011/14128, 2011, A1. Location in patent: Page/Page column 65
5-Bromotryptophol Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromotryptophol Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from 5-Bromotryptophol manufacturers
- Product
- 5-Bromotryptophol 32774-29-1
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-11-21
- Product
- 5-Bromotryptophol 32774-29-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-01
- Product
- 2-(5-bromo-1H-indol-3-yl)ethanol 32774-29-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons
- Release date
- 2020-02-14