2-METHANESULFONYL-PYRIMIDINE
Application- Product Name
- 2-METHANESULFONYL-PYRIMIDINE
- CAS No.
- 14161-09-2
- Chemical Name
- 2-METHANESULFONYL-PYRIMIDINE
- Synonyms
- 2-(Methylsulfonyl)pyrimidine;2-METHANESULFONYL-PYRIMIDINE;Methyl pyrimidin-2-yl sulphone;Pyrimidine, 2-(methylsulfonyl)-;2-METHANESULFONYL-PYRIMIDINE ISO 9001:2015 REACH
- CBNumber
- CB7684944
- Molecular Formula
- C5H6N2O2S
- Formula Weight
- 158.18
- MOL File
- 14161-09-2.mol
2-METHANESULFONYL-PYRIMIDINE Property
- Boiling point:
- 335.6±25.0 °C(Predicted)
- Density
- 1.344±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -3.39±0.13(Predicted)
- form
- solid
- color
- Yellow
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 296312
- Product name
- 2-Methanesulfonyl-pyrimidine
- Packaging
- 250mg
- Price
- $375
- Updated
- 2021/12/16
- Product number
- M339263
- Product name
- 2-(Methylsulphonyl)pyrimidine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- NUC0001228
- Product name
- 2-(METHYLSULPHONYL)PYRIMIDINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $461
- Updated
- 2021/12/16
- Product number
- NM44273
- Product name
- 2-Methanesulfonyl-pyrimidine
- Packaging
- 2g
- Price
- $375
- Updated
- 2021/12/16
- Product number
- 107875
- Product name
- 2-Methanesulfonyl-pyrimidine
- Packaging
- 250mg
- Price
- $390
- Updated
- 2021/12/16
2-METHANESULFONYL-PYRIMIDINE Chemical Properties,Usage,Production
Application
2-Methylsulfonylpyrimidine can be used as a pharmaceutical synthesis intermediate and an organic synthesis intermediate, mainly in laboratory research and development processes and chemical and pharmaceutical synthesis processes.
Synthesis
2-Methylsulfonylpyrimidine was prepared as follows: a suspension of potassium carbonate (27.6 g, 0.2 mol) in a solution of 2-mercaptopyrimidine (0.1 mol) and methyl iodide (18.7 ml, 0.3 mol) in acetone (200 ml) was heated to reflux for a period of 3 hours. The reaction mixture was allowed to cool and then filtered followed by vacuum evaporation. Distillation of the mixture at a pressure of 0.01 mmHg gave 12.7 g of 2-methylthio-4,6-dimethylpyrimidine as a white solid. A portion of this solid (4.42 g, 28.7 mmol) was dissolved in dichloromethane (200 ml) and m-chloroperoxybenzoic acid (50%, 22.8 g, 66.0 mmol) was added in batches. The resulting mixture was stirred for 5 days and finally it was filtered and then evaporated under vacuum. Purification by rapid column chromatography on silica gel, using ether as eluent, gave 2-methylsulfonylpyrimidine as a white solid, m.pt., 81 ??C.
2-METHANESULFONYL-PYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-METHANESULFONYL-PYRIMIDINE manufacturers
- Product
- 2-METHANESULFONYL-PYRIMIDINE 14161-09-2
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-11-12
- Product
- 2-METHANESULFONYL-PYRIMIDINE 14161-09-2
- Price
- US $1.00-1.00/Kg/Drum
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2020-05-14
- Product
- 2-METHANESULFONYL-PYRIMIDINE 14161-09-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons
- Release date
- 2022-02-18