2-MORPHOLINOBENZALDEHYDE
- Product Name
- 2-MORPHOLINOBENZALDEHYDE
- CAS No.
- 58028-76-5
- Chemical Name
- 2-MORPHOLINOBENZALDEHYDE
- Synonyms
- 2-MORPHOLINOBENZALDEHYDE;2-(4-MORPHOLINO)BENZALDEHYDE;4-(2-Formylphenyl)morpholine;2-MORPHOLIN-4-YL-BENZALDEHYDE;2-(4-Morpholinyl)-benzaldehyde;2-MORPHOLINOBENZENECARBALDEHYDE;2-(morpholine-1-yl)benzaldehyde;2- Morpholino-4-yl-benzaldehyde;2-(4-Morpholino)benzaldehyde 97%;Benzaldehyde, 2-(4-morpholinyl)-
- CBNumber
- CB7693157
- Molecular Formula
- C11H13NO2
- Formula Weight
- 191.23
- MOL File
- 58028-76-5.mol
2-MORPHOLINOBENZALDEHYDE Property
- Melting point:
- 45-48°C
- Boiling point:
- 162 °C(Press: 12.0 Torr)
- Density
- 1.163±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.88±0.40(Predicted)
- form
- solid
- color
- Yellow
- InChI
- InChI=1S/C11H13NO2/c13-9-10-3-1-2-4-11(10)12-5-7-14-8-6-12/h1-4,9H,5-8H2
- InChIKey
- GTTAEWVBVHSDLX-UHFFFAOYSA-N
- SMILES
- C(=O)C1=CC=CC=C1N1CCOCC1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M723760
- Product name
- 2-Morpholinobenzaldehyde
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 046044
- Product name
- 2-Morpholinobenzenecarbaldehyde
- Purity
- >95%
- Packaging
- 500mg
- Price
- $181
- Updated
- 2021/12/16
- Product number
- 046044
- Product name
- 2-Morpholinobenzenecarbaldehyde
- Purity
- >95%
- Packaging
- 1g
- Price
- $228
- Updated
- 2021/12/16
- Product number
- COR0001819
- Product name
- 2-MORPHOLIN-4-YL-BENZALDEHYDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $448
- Updated
- 2021/12/16
- Product number
- 046044
- Product name
- 2-Morpholinobenzenecarbaldehyde
- Purity
- >95%
- Packaging
- 5g
- Price
- $524
- Updated
- 2021/12/16
2-MORPHOLINOBENZALDEHYDE Chemical Properties,Usage,Production
Uses
Benzaldehyde derivative.
Synthesis
110-91-8
446-52-6
58028-76-5
Example 180: Synthesis of N-(1-methyl-1H-pyrazol-4-yl)-1-(2-morpholinobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine Step (i): 2-fluorobenzaldehyde (0.5 mL, 4.8 mmol), morpholine (0.6 mL, 1.5 eq.), and potassium carbonate (1.3 g, 2 eq.) were mixed and heated in a microwave reactor at 125 °C for 2.5 hours. Upon completion of the reaction, the solvent was removed by evaporation. The residue was partitioned between water and dichloromethane (DCM) and the aqueous phase was further extracted with DCM. All organic phases were combined, dried over sodium sulfate and subsequently concentrated under vacuum to give 2-morpholino benzaldehyde (0.57 g, 63% yield).
References
[1] Russian Chemical Bulletin, 2004, vol. 53, # 6, p. 1240 - 1247
[2] Synthesis, 2010, # 24, p. 4287 - 4299
[3] Patent: WO2011/48082, 2011, A1. Location in patent: Page/Page column 160; 161
[4] Medicinal Chemistry Research, 2015, vol. 24, # 9, p. 3516 - 3528
[5] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1975, p. 1679 - 1682
2-MORPHOLINOBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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