ChemicalBook > CAS DataBase List > 4-(Aminomethyl)benzonitrile hydrochloride

4-(Aminomethyl)benzonitrile hydrochloride

Product Name
4-(Aminomethyl)benzonitrile hydrochloride
CAS No.
15996-76-6
Chemical Name
4-(Aminomethyl)benzonitrile hydrochloride
Synonyms
4-CYANOBENZYLAMINE HYDROCHLORIDE;4-CNBAM X HCL;4-CyanobenzylaMine HCl Salt;4-(AMINOMETHYL)BENZONITRILE HCL;α-Amino-p-tolunitrile Hydrochloride;ALPHA-AMINO-P-TOLUNITRILE HYDROCHLORIDE;4-(AMINOMETHYL)BENZONITRILE HYDROCHLORIDE;p-(Aminomethyl)benzonitrile Hydrochloride;Benzonitrile,4-(aminomethyl)-, hydrochloride;4-(Aminomethyl)benzonitrile hydrochloride 97%
CBNumber
CB7696815
Molecular Formula
C8H9ClN2
Formula Weight
168.62
MOL File
15996-76-6.mol
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4-(Aminomethyl)benzonitrile hydrochloride Property

Melting point:
274-279 °C(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
Off-White to Yellow
Water Solubility 
almost transparency
CAS DataBase Reference
15996-76-6(CAS DataBase Reference)
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Safety

Risk Statements 
20/21/22-36/37/38-22
Safety Statements 
22-24/25-36/37-26
WGK Germany 
3
HS Code 
29269090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
631396
Product name
4-(Aminomethyl)benzonitrile hydrochloride
Purity
97%
Packaging
5g
Price
$26.5
Updated
2025/07/31
Sigma-Aldrich
Product number
631396
Product name
4-(Aminomethyl)benzonitrile hydrochloride
Purity
97%
Packaging
25g
Price
$102.42
Updated
2025/07/31
TCI Chemical
Product number
A1645
Product name
4-(Aminomethyl)benzonitrile Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$32
Updated
2025/07/31
TCI Chemical
Product number
A1645
Product name
4-(Aminomethyl)benzonitrile Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$68
Updated
2025/07/31
TRC
Product number
C962285
Product name
4-CyanobenzylamineHydrochloride
Packaging
50g
Price
$375
Updated
2021/12/16
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4-(Aminomethyl)benzonitrile hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

4-(Aminomethyl)benzonitrile hydrochloride can be used in the synthesis of fluorescent-labeled bisbenzamidine, which can be a biochemical tool in biomedical studies. It can also be used in the synthesis of 3-(p-benzylamino)-1,2,4,5 tetrazine, used in the modification of alginate hydrogels, employed in cell engineering applications.

Synthesis

10406-25-4

15996-76-6

In a 200 mL four-neck flask equipped with a stirrer, a thermometer, a gas introduction tube, and a reflux condenser, 4-cyanobenzylamine (10.0 g) obtained in Preparation Example 3 was dissolved in ethyl acetate (90.0 g). The reactor was cooled in a water bath under stirring while hydrogen chloride gas was slowly introduced into the gas phase of the reactor. Immediately after the introduction of hydrogen chloride gas, an exothermic phenomenon was observed and a white solid precipitated. After the reaction mixture was cooled to room temperature, the white solid was separated by filtration and dried in a vacuum desiccator to give 12.6 g of 4-(aminomethyl)benzonitrile hydrochloride (99% yield as 4-cyanobenzylamine). The resulting 4-(aminomethyl)benzonitrile hydrochloride was analyzed by high performance liquid chromatography and found to contain 77 wt% of 4-cyanobenzylamine. In addition, anion chromatographic analysis showed 23 wt% of hydrogen chloride in 4-(aminomethyl)benzonitrile hydrochloride. The measured bulk density of 4-(aminomethyl)benzonitrile hydrochloride was 0.3 g/mL.

References

[1] Patent: US6392083, 2002, B1. Location in patent: Page column 6
[2] Patent: US6392083, 2002, B1. Location in patent: Page column 7

4-(Aminomethyl)benzonitrile hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-(Aminomethyl)benzonitrile hydrochloride manufacturers

Career Henan Chemical Co
Product
4-(Aminomethyl)benzonitrile hydrochloride 15996-76-6
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-12-24

15996-76-6, 4-(Aminomethyl)benzonitrile hydrochlorideRelated Search:

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