Identification test Chemical properties Uses Preparation Toxicity
ChemicalBook > CAS DataBase List > NEROL

NEROL

Identification test Chemical properties Uses Preparation Toxicity
Product Name
NEROL
CAS No.
106-25-2
Chemical Name
NEROL
Synonyms
CIS-GERANIOL;(Z)-3,7-DIMETHYL-2,6-OCTADIEN-1-OL;(3Z)-3,7-Dimethyl-2,6-octadiene-1-ol;2,6-Octadien-1-ol,3,7-dimethyl-,(Z)-;Vernol;NEROLEX;NERYL ALCOHOL;Nerol solution;2,6-OCTADIEN-1-OL, 3,7-DIMETHYL;(Z)-3,7-dimethylocta-2,6-dien-1-ol
CBNumber
CB7698233
Molecular Formula
C10H18O
Formula Weight
154.25
MOL File
106-25-2.mol
More
Less

NEROL Property

Melting point:
<-15 °C
Boiling point:
103-105 °C/9 mmHg (lit.)
Density 
0.876 g/mL at 25 °C (lit.)
vapor pressure 
2.39Pa at 20℃
FEMA 
2770 | NEROL
refractive index 
n20/D 1.474(lit.)
Flash point:
226 °F
storage temp. 
2-8°C
solubility 
absolute ethanol: soluble(lit.)
form 
Liquid
pka
14.45±0.10(Predicted)
color 
Clear colorless to almost colorless
Odor
at 100.00 %. sweet natural neroli citrus magnolia
Odor Type
floral
Water Solubility 
1.311g/L(25 ºC)
Merck 
14,6475
JECFA Number
1224
BRN 
1722455
LogP
2.76 at 30℃
CAS DataBase Reference
106-25-2(CAS DataBase Reference)
EPA Substance Registry System
2,6-Octadien-1-ol, 3,7-dimethyl-, (2Z)- (106-25-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
2
RTECS 
RG5840000
TSCA 
Yes
HS Code 
29052210
Hazardous Substances Data
106-25-2(Hazardous Substances Data)
Toxicity
The acute oral LD50 value in rats was reported as 4.5 g/kg (3.4-5.6 g/kg) (Moreno, 1972). The acute dermal LD50 value in rabbits exceeded 5 g/kg (Moreno, 1972).
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W277002
Product name
cis-3,7-Dimethyl-2,6-octadien-1-ol
Purity
≥97%, FCC, FG
Packaging
1kg
Price
$111
Updated
2024/03/01
Sigma-Aldrich
Product number
W277002
Product name
cis-3,7-Dimethyl-2,6-octadien-1-ol
Purity
≥97%, FCC, FG
Packaging
4kg
Price
$403
Updated
2024/03/01
Sigma-Aldrich
Product number
W277002
Product name
cis-3,7-Dimethyl-2,6-octadien-1-ol
Purity
≥97%, FCC, FG
Packaging
9kg
Price
$610
Updated
2024/03/01
Sigma-Aldrich
Product number
268909
Product name
cis-3,7-Dimethyl-2,6-octadien-1-ol
Purity
97%
Packaging
5ml
Price
$31.86
Updated
2024/03/01
Sigma-Aldrich
Product number
268909
Product name
cis-3,7-Dimethyl-2,6-octadien-1-ol
Purity
97%
Packaging
100ml
Price
$41.16
Updated
2024/03/01
More
Less

NEROL Chemical Properties,Usage,Production

Identification test

Determination of total alcohol (OT-5). The amount of sample taken is 1.2g; the equivalent factor (e) in the calculation is 77.13.

Chemical properties

Colorless oily liquid It bears a sweet smell similar to the fresh rose, better than geraniol, and with hints of lemon flavor. The boiling point is 227 ℃; flash point is 92 ℃; optical rotation is [α] D ± 0 °. Miscible in ethanol, chloroform and ether; nearly insoluble in water.
It is the isomer of geraniol (trans; geraniol is cis).
Natural lanolin and its esters are found in orange leaf oil, rose oil, lavender oil, Sri Lanka citronella oil, bitter orange blossom oil and bergamot, lemon, white lemon, grapefruit, sweet orange and so on.

Uses

The food flavors are mainly for the preparation of raspberry, strawberry and citrus fruit flavors and preparation of orange blossom, rose, magnolia main spices. It is a spice commonly used in jasmine, white flowers, lilac, lily of the valley, narcissus, carnation, mimosa, violet, vanilla, cymbidium, tuberose and citrus cologne. It is also commonly used in hyacinth, gardenia, osmanthus, acacia flavor formula. In the food flavor, its raspberry-strawberry flavor effect is commonly used. The product is also used in the preparation of daily makeup fragrance, such as violet, orange blossom, jasmine, lily of the valley, magnolia, cloves and other fragrance type makeup fragrance. It is widely used in orange blossom, rose, jasmine, tuberose and other fragrances of fragrant type and food flavor of raspberry, strawberry. It can also be used to produce ester spices.

Preparation

1. Oil of petitgrain is used as raw material; the first step is eliminating linalool and terpenes through fractionation; through saponification the fraction containing primary alcohol will be made into phthalate esters; and then going through purification and alkali saponification, geraniol (60 %) and nerol (40%) mixture is derived; removing geraniol with lead chloride, undergoing the residue vacuum distillation or steam distillation, the product was derived.
2. Let the geraniol and hydroiodic acid reacted in the neutral solution. Removing excess hydrogen iodide with alkali, the nerol mixed with geraniol can be derived, and then separate the mixture using the above method.
3. Heat the mixture of the same amount of camphor and acetic anhydride to boiling in the presence of sodium acetate. The mixture of geraniol and neryl alcohol can be derived through saponified esterification, and then separate the mixture by the former method.
4. Reducing citral in the isopropanol solution containing isopropanol aluminium also can obtain the mixture of geraniol and nerol, and nerol is derived through re-separation.

Toxicity

GRAS (FEMA).
LD504500 mg/kg (rat, oral).
maximum level    FEMA (mg/kg): soft drink 1.4; cold drink 3.9; candy 16; baked food 19; pudding 1.0 to 1.3;
utilization limitation (FDA $ 172. 515, 2000).

Description

Nerol has a fresh, sweet, rose-like odor and a bitter flavor. Nerol may be synthesized from pinene.

Chemical Properties

Nerol has a fresh, sweet, rose-like odor and a bitter flavor.

Chemical Properties

Clear colorless to almost colorless liquid

Chemical Properties

Nerol occurs in small quantities in many essential oils where it is always accompanied by geraniol; its name originates from its occurrence in neroli oil. Nerol is a colorless liquid with a pleasant rose-like odor, which, unlike that of geraniol, has a fresh green note. Nerol undergoes the same reactions as geraniol but cyclizes more readily in the presence of acids.
Nerol is produced along with geraniol from myrcene in the process described for geraniol. It can be separated from geraniol by fractional distillation.
Nerol is used in perfumery not only for the same purposes as geraniol, for example, in rose compositions, to which it lends a particular freshness, but also in other blossom compositions. In flavor work, it is used for bouquetting citrus flavors. Technical-grade nerol, often in a mixture with geraniol, is used as an intermediate in the production of citronellol and citral.

Occurrence

Reported found in neroli oil (with geraniol) and in the essential oils of lemongrass, Ceylon citronella, ylangylang, champaca, Cayenne Bois de Rose and bergamot; also in lemon, sweet orange and petitgrain bergamot; in clary sage, lavandin, lavender, Mexican linaloe, myrrh, jasmine, Paraguay petitgrain; also reported among the volatile constituents of currant aroma; Helicrysum angustifolium contains up to 30 to 50% nerol. Also reported found in citrus peel oils and juices, apricot, cranberry, blueberry, currant, grapes, papaya, raspberry, blackberry, strawberry, potato, tomato, cinnamon, ginger, mentha oils, mustard, nutmeg, thyme, hop oil, beer, gin, cognac, brandy, grape wines, tea, honey, Arctic bramble, passion fruit, prune, Japanese plum, rose apple, marjoram, mango, tamarind, cardamom, coriander seed and leaf, tarragon, litchi, licorice, buckwheat, laurel, wort, elderberry, cherimoya, myrtle leaf and berry, buchu oil, Bourbon vanilla, lemon balm, clary sage, loganberry, maté, German chamomile oil and mastic gum leaf oil.

Uses

Nerol is a flavoring agent that is a colorless liquid with an odor resem- bling fresh, sweet roses and contains geranoils and other terpenic alcohols. it is miscible in alcohol, chloroform, and ether insoluble in water. it is obtained by synthesis. it is also termed cis-3,7-dime- thyl-2,6-octadien-1-ol.

Uses

Nerol is an isomer of Geraniol (G367000), used in the synthesis of insect repellant. It is also used in the synthesis of Angelicoin A and Herecinone J, which inhibit collagen-induced platelet aggregat ion.

Uses

nerol is a primary alcohol used in perfumes, especially those with rose and orange blossom scents. nerol is a naturally occurring fraction in oil of lavender, orange leaf, palmarosa, rose, neroli, and petitgrain. It is colorless and has a rose-like scent.

Definition

ChEBI: The (2Z)-stereoisomer of 3,7-dimethylocta-2,6-dien-1-ol. It has been isolated from the essential oils from plants like lemon grass.

Preparation

From pinene.

Aroma threshold values

Detection: 680 ppb to 2.2 ppm; aroma characteristics at 2%: rosy, slightly citrus, terpy and floral, reminiscent of linalool oxide with aldehydic waxy and fruity nuances

Taste threshold values

Taste characteristics at 10 ppm in 5% sugar and 0.1% CA: rosy with citrus nuances, fruity pear with floral citronellal notes

Synthesis Reference(s)

Tetrahedron, 40, p. 641, 1984 DOI: 10.1016/S0040-4020(01)91092-0
Tetrahedron Letters, 33, p. 5417, 1992 DOI: 10.1016/S0040-4039(00)79109-X
Synthesis, p. 328, 1988 DOI: 10.1055/s-1988-27559

General Description

The antifungal efficacy of nerol (cis-3,7-Dimethyl-2,6-octadien-1-ol), against Aspergillus flavus, was studied.

Safety Profile

Moderately toxic by intramuscular route. Mildly toxic by ingestion. A skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

NEROL Preparation Products And Raw materials

Raw materials

Geraniol Aluminium isopropoxide Sodium acetate trihydrate Linalool Phthalates Hydriodic acid Esterified product Citral

Preparation Products

Citronellol Geraniol NERYL ISOBUTYRATE Citral
More
Less

NEROL Suppliers

Americas 1 Australia 1 Belgium 2 Brazil 1 Canada 1 China 260 Europe 2 France 2 Germany 7 India 23 Italy 1 Japan 7 Mexico 1 Singapore 1 South Africa 1 Spain 5 Switzerland 2 United Kingdom 9 United States 77 Global 404
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
Nice Group Inc
Tel
--
Fax
--
Email
Amy@nicegroupinc.com
Country
United States
ProdList
134
Advantage
58
Parchem Fine & Specialty Chemicals
Tel
--
Fax
--
Email
info@parchem.com
Country
United States
ProdList
1031
Advantage
58
Advanced Biotech - ABT
Tel
--
Fax
--
Country
United States
ProdList
260
Advantage
58
Penta Manufacturing Company (a division of Penta International Corporation)
Tel
--
Fax
--
Email
@pentamfg.com
Country
United States
ProdList
901
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
Selleck Chemicals LLC
Tel
--
Fax
--
Email
sales@selleckchem.com
Country
United States
ProdList
1848
Advantage
58
Fleurchem Inc.,
Tel
--
Fax
--
Country
United States
ProdList
119
Advantage
58
International Flavors & Fragrances Inc. (IFF)
Tel
--
Fax
--
Email
info@lucasmeyercosmetics.com
Country
United States
ProdList
53
Advantage
58
AA Blocks LLC
Tel
--
Fax
--
Email
s@aablocks.com
Country
United States
ProdList
536
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Citrus and Allied Essences Ltd.
Tel
--
Fax
--
Email
galloca@citrusandallied.com
Country
United States
ProdList
90
Advantage
58
Ambeed, Inc.
Tel
--
Fax
--
Email
info@ambeed.com
Country
United States
ProdList
502
Advantage
58
Berje Inc.
Tel
--
Fax
--
Email
tlauzurica@berjeinc.com
Country
United States
ProdList
958
Advantage
58
Lluch Essence S.L.
Tel
--
Fax
--
Email
web@lluche.com
Country
United States
ProdList
2352
Advantage
58
Prodasynth
Tel
--
Fax
--
Email
info@prodasynth.com
Country
United States
ProdList
423
Advantage
58
Taytonn ASCC Pte Ltd
Tel
--
Fax
--
Email
info@taytonnascc.com
Country
United States
ProdList
742
Advantage
58
TCI America, Inc. (part of Tokyo Chemical Industry)
Tel
--
Fax
--
Email
Angelina.Crew@tcichemicals.com
Country
United States
ProdList
2053
Advantage
58
Elan Chemical Inc.
Tel
--
Fax
--
Email
sales@elan-chemical.com
Country
United States
ProdList
114
Advantage
65
Auro Chemicals
Tel
--
Fax
--
Email
customerservice@aurochemicals.com
Country
United States
ProdList
246
Advantage
58
Vigon International, Inc.
Tel
--
Fax
--
Email
jpassamonte@vigoninternational.com
Country
United States
ProdList
1268
Advantage
64
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Phoenix Aromas & Essential Oils, LLC
Tel
--
Fax
--
Country
United States
ProdList
41
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
The Good Scents Company
Tel
--
Fax
--
Email
goodscnt@thegoodscentscompany.com
Country
United States
ProdList
160
Advantage
58
Pell Wall Perfumes
Tel
--
Fax
--
Email
//pellwall.com/contact-us/
Country
United States
ProdList
559
Advantage
58
M&U International LLC
Tel
--
Fax
--
Email
sales@mu-intel.com
Country
United States
ProdList
2011
Advantage
58
Alfrebro LLC/ Archer Daniels Midland Company
Tel
--
Fax
--
Email
sforbis@alfrebro.com
Country
United States
ProdList
768
Advantage
58
Moellhausen S.P.A.
Tel
--
Fax
--
Country
United States
ProdList
1676
Advantage
58
ECSA Chemicals
Tel
--
Fax
--
Email
marketing@ecsa.ch
Country
United States
ProdList
1735
Advantage
58
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
Elan Inc.
Tel
--
Fax
--
Email
dpimentel@elan-chemical.com
Country
United States
ProdList
116
Advantage
58
Pyrazine Specialties, Inc.
Tel
--
Fax
--
Country
United States
ProdList
1265
Advantage
30
Indukern, S.A. F&F Ingredients Division
Tel
--
Fax
--
Email
info@indukern.es
Country
United States
ProdList
1321
Advantage
58
Fleurchem, Inc.
Tel
--
Fax
--
Email
info@fleurchem.com
Country
United States
ProdList
790
Advantage
58
Ernesto Ventós S.A.
Tel
--
Fax
--
Email
info@ventos.com
Country
United States
ProdList
2257
Advantage
58
Advanced Biotech. Inc.
Tel
--
Fax
--
Email
info@adv-bio.com
Country
United States
ProdList
1121
Advantage
58
Excellentia International
Tel
--
Fax
--
Email
info@excellentiaint.com
Country
United States
ProdList
567
Advantage
58
Zanos Ltd.
Tel
--
Fax
--
Email
sales@zanos.co.uk
Country
United States
ProdList
444
Advantage
58
The John D. Walsh Company, Inc
Tel
--
Fax
--
Email
info@johndwalsh.com
Country
United States
ProdList
1139
Advantage
58
Vigon International
Tel
--
Fax
--
Email
sales@vigon.com
Country
United States
ProdList
1776
Advantage
58
CJ Latta & Associates, LLC
Tel
--
Fax
--
Email
chiplatta@msn.com
Country
United States
ProdList
357
Advantage
58
R C Treatt and Co Ltd
Tel
--
Fax
--
Email
enquiries@treatt.com
Country
United States
ProdList
1690
Advantage
58
More
Less

View Lastest Price from NEROL manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
NEROL 106-25-2
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-20
Shandong Deshang Chemical Co., Ltd.
Product
NEROL 106-25-2
Price
US $10.00-7.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
10 tons
Release date
2024-06-07
Hebei Weibang Biotechnology Co., Ltd
Product
Nerol 106-25-2
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-08

106-25-2, NEROLRelated Search:

NEROL ACETATE TRANS-NEROL Glycerol Citric acid HENEICOSAPRENOL VETIVEROL UNDECAPRENOL NEROL OXIDE NERYL PROPIONATE 1,2,3,3a,4,5,6,8a-octahydro-2-isopropylidene-4,8-dimethylazulen-6-yl acetate FEMA 2774 NERYL ISOBUTYRATE NEROL NERYL FORMATE NERYL PYROPHOSPHATE, [1-3H] CIS, CIS FARNESOL, [1-3H] FEMA 2778 TSCHIMGANIDINE

  • (3Z)-3,7-Dimethyl-2,6-octadiene-1-ol
  • NEROL EXTRA LG FCC
  • NEROL PRIME
  • NEROL, NATURAL
  • cis-3,7-Dimethyl-2,6-octadien-1-ol, Nerol
  • Nerol,97%
  • Nerol,cis-3,7-Dimethyl-2,6-octadien-1-ol
  • cis-3,7-Dimethyl-2,6-octadien-1-ol,cis-3,7-Dimethyl-2,6-octadien-1-ol, Nerol
  • beta-nerol
  • cis-3,7-dimethyl-octa-2,6-dien-1-ol
  • Vernol
  • Nerol, 98%, from rose refined oil
  • nerol,(Z)-3,7-dimethyl-2,6-octadien-1-ol
  • 2,6-Octadien-1-ol, 3,7-dimethyl-, (2Z)-
  • (2E)-3,7-dimethylocta-2,6-dien-1-ol
  • NEROL(SG)
  • DIMETHYLOCTADIENOL
  • NEROL WITH GC
  • Neraniol
  • Nerol, 97% 100ML
  • cis-3,7-DiMethyl-2,6-octadien-1-ol 97%
  • 3, 7-DIMETHYL-CIS-2, 6-OCTADIEN-1-OL
  • (Z)-3,7-dimethylocta-2,6-dien-1-ol
  • NEROLEX FCC
  • NEROL 97+% FCC
  • (2Z)-3,7-Dimethyl-2,6-octadien-1-ol
  • 2, 6-DIMETHYL-CIS-2, 6-OCTADIEN-8-OL
  • 2,6-OCTADIEN-1-OL, 3,7-DIMETHYL
  • 2,6-DIMETHYL-2,6-OCTADIEN-8-OL
  • CIS-GERANIOL
  • CIS-3,7-DIMETHYL-2,6-OCTADIEN-1-OL
  • FEMA 2770
  • NEROL BJ
  • NEROLEX
  • NEROL
  • NEROL 70
  • NERYL ALCOHOL
  • (Z)-3,7-DIMETHYL-2,6-OCTADIEN-1-OL
  • (Z)-geraniol
  • 2,6-Octadien-1-ol,3,7-dimethyl-,(Z)-
  • 2-cis-3,7-Dimethyl-2,6-octadien-1-ol
  • 3,7-dimethyl-octa-2cis,6-dien-1-ol
  • 6-Octadien-1-ol,3,7-dimethyl-,(Z)-2
  • 7-dimethyl-6-octadien-1-o(z)-3
  • Nerol, froM rose refined oil
  • NEROL BRI (98+%) FCC
  • Nerol solution
  • Nerol&gt
  • cis-3,7-Dimethyl-2,6-octadien-1-ol,>98%
  • NEROL 98%*
  • Top quality factory provide Nerol CAS 106-25-2 in stock Vernol
  • Nerol / (3Z)-3,7-Dimethyl-2,6-octadiene-1-ol
  • Difenidolo
  • (2Z)-3,7-dimethylocta-2,6-dien-1-ol
  • Nerol 1000 μg/mL in Isopropanol
  • Cis-Geraniol|||Neryl alcohol
  • Nerol in isooctane
  • 106-25-2