FORTUNELLIN

Product Name: FORTUNELLIN
CAS No.: 20633-93-6
Chemical Name: FORTUNELLIN
Synonyms: FORTUNELLIN;ACACETIN-7-NEOHESPERIDOSIDE;ACACETIN-7-O-NEOHESPERIDOSIDE;4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-
CBNumber: CB7713662
Molecular Formula: C28H32O14
Formula Weight: 592.55
MOL File: 20633-93-6.mol

More

Less

FORTUNELLIN Property

Melting point:: 193-198°C
Boiling point:: 888.7±65.0 °C(Predicted)
Density: 1.62±0.1 g/cm3(Predicted)
pka: 6.10±0.40(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: OA71574
Product name: Acacetin-7-neohesperidoside
Packaging: 5mg
Price: $800
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0029941
Product name: FORTUNELLIN
Purity: 95.00%
Packaging: 5MG
Price: $933.82
Updated: 2021/12/16

Biosynth Carbosynth

Product number: OA71574
Product name: Acacetin-7-neohesperidoside
Packaging: 10mg
Price: $1200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: OA71574
Product name: Acacetin-7-neohesperidoside
Packaging: 25mg
Price: $2500
Updated: 2021/12/16

Biosynth Carbosynth

Product number: OA71574
Product name: Acacetin-7-neohesperidoside
Packaging: 1mg
Price: $300
Updated: 2021/12/16

More

Less

FORTUNELLIN Chemical Properties,Usage,Production

Description

Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation.

Chemical Properties

Off-white to light yellow Solid

Uses

Fortunellin is a flavonoid that can be isolated from kumquat (Fortunella margarita) fruit. Studies have shown that Fortunellin inhibits LPS-induced inflammation and ROS production in H9C2 cells, and also prevents fructose-induced inflammation and oxidative stress by enhancing the AMPK/Nrf2 pathway. In addition, Fortunellin has a dual role in the prevention and treatment of coronaviral disease, with antiviral activity against SARS-CoV-2 and anti-inflammatory immunomodulatory capacity in the host.

Biological Functions

Fortunellin (acacetin 7-O-neohesperidoside) is a citrus flavonoid isolated from kumquat fruit. Kumquat extract has attracted much attention recently for its beneficial effects on human health, which include antitumor, antioxidant and anti-inflammatory characteristics . The beneficial effects of flavonoids on IBD have been confirmed in many studies. However, although fortunellin is the main flavonoid in kumquat, there is a lack of information on its alleviation of IBD.

Mechanism of action

Fortunellin is a citrus flavonoid that is a potential anti-inflammation agent in inflammatory diseases. Fortunellin ameliorated colitis symptoms, including excessive inflammation and oxidative stress. Fortunellin decreased epithelial cell apoptosis through inhibiting PTEN expression in colitis. Fortunellin-induced downregulation of PTEN could be counteracted by miR-374a depletion. Moreover, knockdown of miR-374a in vivo partly inhibited the effects of fortunellin on rat colitis.

FORTUNELLIN Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

FORTUNELLIN Suppliers

China 30 Germany 2 Japan 1 United Kingdom 5 United States 7 Global 45

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40240
Advantage: 62

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9636
Advantage: 58

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 7059
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8012
Advantage: 62

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9175
Advantage: 60

Beijing LAL Pharmaceutical Co., Ltd.

Tel: 010-010-62452898 13581984929
Fax: 010-62452898
Email: jlzhang929@163.com
Country: China
ProdList: 80
Advantage: 58

Nanjing Digger Medical Technology Co. Ltd.

Tel: 025-025-51191215 18013836722
Fax: 025-51191215
Email: 2399235533@qq.com
Country: China
ProdList: 4933
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55896
Advantage: 58

Finetech Industry Limited

Tel: +86-27-87465837 +8618971612321
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9635
Advantage: 58

Hubei yongkuo Technology Co., Ltd

Tel: 027-59223108 15972152991
Fax: 027-59223108
Email: 1248580099@qq.com
Country: China
ProdList: 10007
Advantage: 58

Hubei Xinkang Pharmaceutical Chemical Co., Ltd

Tel: 027-027-59308705 18871579363
Fax: 027-59308705
Email: 1248680011@qq.com
Country: China
ProdList: 9984
Advantage: 58

Hubei Shishun Biotechnology Co. Ltd

Tel: 027-59223025 15107168801
Fax: 027-59223025
Email: 1718480011@qq.com
Country: China
ProdList: 9990
Advantage: 58

Hubei Baidu Chemical Co., Ltd

Tel: 13627137652
Fax: 027-59223020
Email: 1438180055@qq.com
Country: China
ProdList: 9994
Advantage: 58

Hubei Guangao Biotechnology Co., Ltd

Tel: 027-027-59223056 18162699093
Fax: 027-59223056
Email: 1208480011@qq.com
Country: China
ProdList: 9951
Advantage: 58

Hubei Wande Chemical Co., Ltd

Tel: 027-59210159 15377098680
Fax: 027-59210159
Email: 1148280011@qq.com
Country: China
ProdList: 9994
Advantage: 58

Tianmen Hengchang Chemical Co., Ltd

Tel: 027-59322316 15172518801
Fax: 027-59322316
Email: 1208480077@qq.com
Country: China
ProdList: 9942
Advantage: 58

Hubei Qifei Pharmaceutical Chemical Co., Ltd

Tel: 027-027-59322506 18071128681
Fax: 027-59322506
Email: 1438082200@qq.com
Country: China
ProdList: 9995
Advantage: 58

Hubei xingongli Chemical Co., Ltd

Tel: 027-59503710 15172325309
Fax: 027-59503710
Email: 1400858877@qq.com
Country: China
ProdList: 9965
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9209
Advantage: 58

Shanghai Moqi Biological Technology Co., LTD

Tel: 021-38218169 13341702378
Email: 190129269@qq.com
Country: China
ProdList: 9111
Advantage: 58

Hubei DAHAO Chemical Co., Ltd.

Tel: 027-59106191 13986041085
Email: 1400868877@qq.com
Country: China
ProdList: 9987
Advantage: 58

Hubei Tuobang Chemical Co., Ltd.

Tel: 027-59106185 13986181695
Email: 1466039@qq.com
Country: China
ProdList: 9995
Advantage: 58

Wuhan Jingkangen Biomedical Technology Co., Ltd

Tel: 13720134139 13720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 4959
Advantage: 58

Hubei Chenghai Chemical Co., Ltd

Tel: 027-59220433 18327245847
Email: 112699200@qq.com
Country: China
ProdList: 9992
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: rose.shi@synzest.com
Country: China
ProdList: 6111
Advantage: 58

Wuhan Huangzhen Biochemical Co., Ltd

Tel: 13795480948 13795480948
Email: 3450865996@qq.com
Country: China
ProdList: 4958
Advantage: 58

20633-93-6, FORTUNELLINRelated Search:

Acacetin FORTUNELLIN(RG) FORTUNELLIN(P) FORTUNELLIN(REAGENT / STANDARD GRADE) RHOIFOLIN 1-(2,4-DIETHOXY-PHENYL)-ETHANONE 4'-FORMYLPHENYL-BETA-D-GLUCOPYRANOSIDE 3',5'-Dimethoxytricetin 7-O-β-D-glucopypranoside FORTUNELLIN 7-HYDROXYFLAVONE-BETA-D-GLUCOSIDE NEOHESPERIDOSE Neoisoliquiritin L-PICEIN

ACACETIN-7-NEOHESPERIDOSIDE

ACACETIN-7-O-NEOHESPERIDOSIDE

FORTUNELLIN

4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-

20633-93-6

C28H32O14

Tri-substituted Flavones