6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE

Product Name: 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE
CAS No.: 63744-22-9
Chemical Name: 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE
Synonyms: 8-dibroMoiMidazo[1;6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE;6,8-Dibromoimidazol[1,2-a]pyrazine;IMidazo[1,2-a]pyrazine, 6,8-dibroMo-;6,8-Dibromoimidazo[1,2-a]pyrazine>6,8-Dibromoimidazo[1,2-a]pyrazine,95%;6,8-Dibromo imidazole [1,2-A] pyrazine
CBNumber: CB7726277
Molecular Formula: C6H3Br2N3
Formula Weight: 276.92
MOL File: 63744-22-9.mol

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6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE Property

Melting point:: 165.0 to 169.0 °C
Density: 2.35±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystal
pka: -0.36±0.30(Predicted)
color: White to Amber
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C6H3Br2N3/c7-4-3-11-2-1-9-6(11)5(8)10-4/h1-3H
InChIKey: UQCZZGIPIMJBCL-UHFFFAOYSA-N
SMILES: C12=NC=CN1C=C(Br)N=C2Br

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: D4967
Product name: 6,8-Dibromoimidazo[1,2-a]pyrazine
Purity: >98.0%(GC)
Packaging: 1g
Price: $54
Updated: 2025/07/31

TCI Chemical

Product number: D4967
Product name: 6,8-Dibromoimidazo[1,2-a]pyrazine
Purity: >98.0%(GC)
Packaging: 5g
Price: $192
Updated: 2025/07/31

TRC

Product number: D425495
Product name: 6,8-Dibromoimidazo[1,2-a]pyrazine
Packaging: 10g
Price: $1230
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: CAPOD11638
Product name: 6,8-Dibromoimidazo[1,2-a]pyrazine
Purity: 98%
Packaging: 1g
Price: $25
Updated: 2021/12/16

Apolloscientific

Product number: OR16939
Product name: 6,8-Dibromoimidazo[1,2-a]pyrazine
Packaging: 5g
Price: $41
Updated: 2021/12/16

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6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE Chemical Properties,Usage,Production

Uses

6,8-Dibromoimidazo[1,2-a]pyrazine is a imidazopyrazine derivative with uterine-relaxing, antibronchospastic, and cardiac-stimulating properties. 6,8-Dibromoimidazo[1,2-a]pyrazine also displays theophylline-like properties.

Uses

It is an Intermediate in organic syntheses.

Synthesis

7252-83-7

24241-18-7

63744-22-9

1. 3,5-dibromopyrazin-2-amine (1018 g, 4.03 mol) was dissolved in water (10 kg) at room temperature. 2. 2-bromo-1,1-dimethoxyethane (1.79 kg, 4.14 mol) was added to the above solution and mixed with stirring. 3. The reaction mixture was heated to reflux and held for 2 hours. 4. After the reaction was complete, water (15.3 kg) and sodium bicarbonate (744 g) were added to the reaction solution and stirring was continued for 15 minutes. 5. The reaction mixture was filtered and the solid product was collected. 6. 6. After drying, 6,8-dibromoimidazo[1,2-A]pyrazine (1106 g, 3.99 mmol, 99% yield) was obtained as a brown solid. 7. The structure of the product was confirmed by 1H-NMR (400 MHz, DMSO-d6): δ 7.90 (s, 1H), 8.23 (s, 1H), 9.02 (s, 1H).

References

[1] Patent: US2012/59162, 2012, A1. Location in patent: Page/Page column 53-54
[2] Patent: WO2005/85252, 2005, A1. Location in patent: Page/Page column 37-38; 40-41
[3] Journal of Medicinal Chemistry, 2015, vol. 58, # 1, p. 512 - 516
[4] Patent: WO2016/209895, 2016, A1. Location in patent: Paragraph 15; 16

6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE Suppliers

Americas 1 Canada 1 China 205 Czech Republic 1 Europe 1 Germany 4 Hungary 1 India 6 Japan 1 The Netherlands 1 United Kingdom 3 United States 29 Global 254

Toronto Research Chemicals

Tel: --
Fax: --
Email: info@trc-canada.com
Country: Canada
ProdList: 6038
Advantage: 71

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View Lastest Price from 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE 63744-22-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 2000
Release date: 2025-08-29

Career Henan Chemical Co

Product: 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE 63744-22-9
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-24

63744-22-9, 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINERelated Search:

Acetylene 1,4-Dibromobenzene 1,2-DIBROMOETHYLENE Dibromomethane ACETONE-D6 IMidazo[1,2-a]pyridine, 6,8-dibroMo- Imidazo[1,2-a]pyrazin-8-amine (9CI) 6-bromoimidazo[1,2-a]pyrazin-8-amine 6,8-dibromo-[1,2,4]triazolo[1,5-a]pyrazine 6,8-Dibromo-2-methylimidazo[1,2-a]pyrazine 6,8-Dibromoimidazo[1,2-a]pyrazine-3-carbaldehyde 3,5-Dibromo-imidazo[1,2-a]pyrazine 6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE IMIDAZO[1,2-A]PYRAZINE 6-Bromoimidazo[1,2-a]pyrazine 2-(Bromomethyl)imidazole

6,8-DIBROMOIMIDAZO[1,2-A]PYRAZINE

6,8-Dibromoimidazol[1,2-a]pyrazine

IMidazo[1,2-a]pyrazine, 6,8-dibroMo-

8-dibroMoiMidazo[1

6,8-Dibromoimidazo[1,2-a]pyrazine&gt

6,8-Dibromoimidazo[1,2-a]pyrazine,95%

6,8-Dibromo imidazole [1,2-A] pyrazine

63744-22-9

C6H3Br2N3

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

CHIRAL CHEMICALS

Heterocycles series