4-Fluorophenethylamine Property

Boiling point:

50-52 °C/0.15 mmHg (lit.)

Density 

1.061 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5072(lit.)

Flash point:

174 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

pka

9.84±0.10(Predicted)

form 

Liquid

Specific Gravity

1.061

color 

Yellow

Water Solubility 

Slightly soluble in water.

InChI

InChI=1S/C8H10FN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5-6,10H2

InChIKey

CKLFJWXRWIQYOC-UHFFFAOYSA-N

SMILES

C1(CCN)=CC=C(F)C=C1

CAS DataBase Reference

1583-88-6(CAS DataBase Reference)

Safety

Hazard Codes 

T,C

Risk Statements 

23/24/25-34

Safety Statements 

26-27-36/37/39-45

RIDADR 

UN 2922 8/PG 2

WGK Germany 

3

HazardClass 

8

PackingGroup 

Ⅱ

HS Code 

29214200

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H300Fatal if swallowed

H301Toxic if swalloed

H310Fatal in contact with skin

H311Toxic in contact with skin

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H330Fatal if inhaled

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P405Store locked up.

4-Fluorophenethylamine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

4-Fluorophenethylamine may be employed as nucleophile in the synthesis of 2-amino-4-arylpyrimidine derivatives. It is suitable for use in the preparation of ortho-metalated primary phenethylamines having electron-releasing and electron-withdrawing groups on the aromatic ring, leading to complexes containing six membered palladacycles.

Application

Firstly, ethyl 2-cyano-3,3-dimethythioacrylate was prepared from reactions of ethyl cyanoacetate with carbon disulfide and dimethyl sulfate. Secondly, it reacted with 4-fluorophenethylamine to yield ethyl 2-cyano-3-methythioacrylate-3-[2-(4- fluorophenyl)-ethylamino]-acrylate.

Precautions

Stable under recommended storage conditions. Incompatible with oxidizing agents and acids.