Uses
ChemicalBook > CAS DataBase List > 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE

Uses
Product Name
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
CAS No.
1964-77-8
Chemical Name
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
Synonyms
2-Methy-5-bromobenzimidazole;5-bromo-2-methybenzimidazole;5-BROMO-2-METHYLBENZIMIDAZOLE;5-Bromo-2-methylbenzoimidazole;5-BROMO-2-METHYL-1H-BENZIMIDAZOLE;5-Bromo-2-methyl-1H-benzoimidazole;1H-BenziMidazole, 6-broMo-2-Methyl-;5-broMo-2-Methyl-1H-1,3-benzodiazole;5-BROMO-2-METHYL-1H-BENZ(D)IMIDAZOLE;6-bromo-2-methyl-1H-benzo[d]imidazole
CBNumber
CB7733608
Molecular Formula
C8H7BrN2
Formula Weight
211.06
MOL File
1964-77-8.mol
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5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Property

Melting point:
214-215 °C
Boiling point:
397.3±15.0 °C(Predicted)
Density 
1.654±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
10.50±0.10(Predicted)
Appearance
Light yellow to yellow Solid
InChI
InChI=1S/C8H7BrN2/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3,(H,10,11)
InChIKey
FHDFUQGJYYGLHJ-UHFFFAOYSA-N
SMILES
C1(C)NC2=CC(Br)=CC=C2N=1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ANV00243
Product name
5-Bromo-2-methyl-1<I>H</I>-benzimidazole
Purity
Aldrich<SUP>CPR</SUP>
Packaging
1 g
Price
$185
Updated
2025/07/31
TRC
Product number
B697035
Product name
5-Bromo-2-methylbenzoimidazole
Packaging
500mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
J54672
Product name
5-Bromo-2-methyl-1H-benzimidazole
Packaging
10g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
119046
Product name
5-Bromo-2-methyl-1H-benzo[d]imidazole
Purity
95+%
Packaging
1g
Price
$82
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB44915
Product name
5-Bromo-2-methyl-1H-benzo[d]imidazole
Packaging
2g
Price
$200
Updated
2021/12/16
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5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Chemical Properties,Usage,Production

Uses

5-Bromo-2-methyl-1H-benzo[D]imidazole is a benzo[D]imidazole derivative. Benzimidazole compounds possess biological activities such as anti-HIV-1 activity, anti-tumor activity, anti-cell proliferation activity, anti-parasitic activity, anti-inflammatory activity, antioxidant activity, and anti-epileptic activity. In addition, these compounds are also used as metal ligands. Therefore, the synthesis of these compounds has attracted considerable attention from chemists.

Synthesis

78-39-7

1575-37-7

1964-77-8

GENERAL METHOD: A mixture of 4-bromophthalimide (1.0 mmol), triethyl orthoacetate (1.2 mmol) and ZrCl4 (0.1 mmol) in 10 mL of methanol was stirred at room temperature for 3 hours. Upon completion of the reaction, the progress was monitored by TLC and the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent ratio of petroleum ether/ethyl acetate (4:1 to 1:1, v/v) to afford the target compound 5-bromo-2-methyl-1H-benzo[D]imidazole.

References

[1] European Journal of Medicinal Chemistry, 2015, vol. 90, p. 241 - 250

5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-METHYL-1H-BENZIMIDAZOLE Suppliers

China 124 France 1 India 5 United Kingdom 2 United States 14 Global 146
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
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View Lastest Price from 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Bromo-2-Methyl-1H-Benzimidazole 1964-77-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Bromo-2-Methyl-1H-Benzimidazole 1964-77-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
5-BROMO-2-METHYL-1H-BENZIMIDAZOLE 1964-77-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-20

1964-77-8, 5-BROMO-2-METHYL-1H-BENZIMIDAZOLERelated Search:

5-Bromo-1H-Benzo[d]Imidazole-2-Carboxylic Acid 6-BROMO-1H-BENZOIMIDAZOLE-2-CARBOXYLIC ACID METHYL ESTER 2-(HYDROXYMETHYL)-5-BROMO-1H-BENZOIMIDAZOLE 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE 6-Bromo-1-methyl-1H-benzimidazole 1H-BENZIMIDAZOLE, 6-BROMO-2-(TRIFLUOROMETHYL)- 3-(5-BROMO-1H-BENZOIMIDAZOL-2-YL)-PROPAN-1-OL 5-bromo-2-(chloromethyl)-1H-benzo[d]imidazole 4-BROMO-2-METHYL-1H-BENZIMIDAZOLE 5-BROMO-6-METHYL-1H-BENZIMIDAZOLE 4-(5-BROMO-1 H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE 5-BROMO-1H-BENZIMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER 3-(5-BROMO-1 H-BENZOIMIDAZOL-2-YL)-PHENYLAMINE 1-(5-BROMO-1H-BENZOIMIDAZOL-2-YL)-ETHANOL 6-BROMO-2-(PIPERIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE 5-Bromobenzimidazole-2-carboxaldehyde 5-BROMO-1-METHYL-1H-BENZIMIDAZOLE AURORA KA-316

  • 5-BROMO-2-METHYL-1H-BENZIMIDAZOLE
  • 5-BROMO-2-METHYL-1H-BENZO[D]IMIDAZOLE
  • 5-BROMO-2-METHYLBENZIMIDAZOLE
  • 5-BROMO-2-METHYL-1H-BENZ(D)IMIDAZOLE
  • 5-Bromo-2-methylbenzoimidazole
  • 1H-BenziMidazole, 6-broMo-2-Methyl-
  • 5-broMo-2-Methyl-1H-1,3-benzodiazole
  • 5-Bromo-2-methyl-1H-benzoimidazole
  • 5-bromo-2-methybenzimidazole
  • 2-Methy-5-bromobenzimidazole
  • 6-bromo-2-methyl-1H-benzo[d]imidazole
  • 5-Bromo-2-methyl-1<i>H</i>-benzimidazole
  • 1964-77-8
  • C8H7BrN2