ChemicalBook > CAS DataBase List > FMOC-SER-OME

FMOC-SER-OME

Product Name
FMOC-SER-OME
CAS No.
82911-78-2
Chemical Name
FMOC-SER-OME
Synonyms
FMOC-SER-OME;Fmoc-L-Ser-OMe;FMOC-SERINE-OME;Fmoc-Ser-Ome, ≥98%;Tryptophan Impurity 78;Ceftobiprole Impurity 19;FMOC-L-SERINE METHYL ESTER;Fmoc-L-β-hydroxyalanine methyl ester;Fmoc-L-serine methyl ester≥ 99.5% (HPLC);(9H-Fluoren-9-yl)MethOxy]Carbonyl Ser-OMe
CBNumber
CB7736311
Molecular Formula
C19H19NO5
Formula Weight
341.36
MOL File
82911-78-2.mol
More
Less

FMOC-SER-OME Property

Boiling point:
579.4±45.0 °C(Predicted)
Density 
1.285±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
form 
Solid
pka
10.07±0.46(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
F861045
Product name
Fmoc-Ser-OMe
Packaging
250mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
J96847
Product name
Fmoc-L-serinemethylester
Packaging
250mg
Price
$15
Updated
2021/12/16
Activate Scientific
Product number
AS88997
Product name
Fmoc-L-serine methyl ester
Purity
97% ee
Packaging
1g
Price
$49
Updated
2021/12/16
Chem-Impex
Product number
03925
Product name
Fmoc-L-serinemethylester,99.5%(HPLC)
Purity
99.5%(HPLC)
Packaging
250MG
Price
$56
Updated
2021/12/16
Chem-Impex
Product number
03925
Product name
Fmoc-L-serinemethylester,≥99.5%(HPLC)
Purity
≥99.5%(HPLC)
Packaging
1G
Price
$110.66
Updated
2021/12/16
More
Less

FMOC-SER-OME Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor[1][2].

Synthesis

5680-80-8

82911-69-1

82911-78-2

GENERAL STEPS: To a mixed solution of 1,4-dioxane (15 mL) and water (90 mL) containing L-serine methyl ester hydrochloride (10.0 g, 64.3 mmol), sodium bicarbonate (10.8 g, 129 mmol) was added. The reaction mixture was stirred at room temperature for 15 minutes. Subsequently, a solution of 1,4-dioxane (60 mL) of 2,5-dioxopyrrolidin-1-yl 9H-fluoren-9-ylmethyl carbonate (21.7 g, 64.3 mmol) was slowly added to the reaction system, and stirring was continued at room temperature for 14 hours. Upon completion of the reaction, water was added to the reaction mixture and extracted three times with ethyl acetate. The organic layers were combined and washed sequentially with water and saturated brine. The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Ether and heptane were added to the residue and the precipitate was collected by filtration to give fmoc-L-serine methyl ester (22.3 g, yield: quantitative). The product was characterized by 1H-NMR (400 MHz, CDCl3): δ 2.00-2.15 (1H, m), 3.81 (3H, s), 3.89-4.07 (2H, m), 4.20-4.28 (1H, m), 4.39-4.53 (3H, m), 5.63-5.74 (1H, m), 7.29-7.37 (2H , m), 7.38-7.46 (2H, m), 7.55-7.65 (2H, m), 7.74-7.82 (2H, m).

References

[1] Tamiaki H, et al. Synthesis of chlorophyll-amino acid conjugates as models for modification of proteins with chromo/fluorophores. Bioorg Med Chem. 2014 Feb 15;22(4):1421-8. DOI:10.1016/j.bmc.2013.12.059
[2] K?rkk?inen TS, et al. Iodine-mediated glycosylation en route to mucin-related glyco-aminoacids and glycopeptides. Carbohydr Res. 2008 Jul 21;343(10-11):1830-4. DOI:10.1016/j.carres.2008.03.034

FMOC-SER-OME Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

FMOC-SER-OME Suppliers

China 76 India 2 Japan 2 United States 10 Global 90
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Rosewell Industry Co., Ltd.
Tel
--
Fax
--
Email
synbiochem@gmail.com
Country
United States
ProdList
310
Advantage
0
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
More
Less

View Lastest Price from FMOC-SER-OME manufacturers

Career Henan Chemical Co
Product
FMOC-SER-OME 82911-78-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20kg
Release date
2018-08-22

82911-78-2, FMOC-SER-OMERelated Search:

Fmoc-L-Glutamic acid gamma-methyl ester FMOC-L-BETA-HOMOMETHIONINE FMOC-ILE-OL Fmoc-Ile-OH Boc-L-Glutamic acid 1-benzyl ester Fmoc-D-Aspartic acid beta-tert-butyl ester FMOC-GLU-OALL Fmoc-L-Serine FMOC-SER-OME O-(2-Azido-4,6-O-benzylidene-2-deoxy-alpha-D-galactopyranosyl)-N-Fmoc-L-serine tert-Butyl Ester O-(2-Azido-4,6-O-benzylidene-2-deoxy-alpha-D-galactopyranosyl)-N-Fmoc-L-threonine tert-Butyl Ester FMOC-L-SER(TBU)-O-CH2-PHI-OCH2-CH2-COOH FMOC-SER(TBU)-OPFP Fmoc-O-tert·butyl-L-threonineN-carboxyanhydride 3-O-Benzoyl-N-acetyl-a-D-galactosaminyl-1-O-N-(Fmoc)serine Phenacylester NALPHA-FMOC-L-SERINE TERT-BUTYL ESTER FMOC-THR(TBU)-OPFP NALPHA-FMOC-L-THREONINE TERT-BUTYL ESTER

  • (S)-Methyl 2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-hydroxypropanoate
  • FMOC-L-SERINE METHYL ESTER
  • FMOC-SERINE-OME
  • FMOC-SER-OME
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-SERINE METHYL ESTER
  • Fmoc-L-Ser-OMe
  • (S)-Fmoc-2-Amino-3-hydroxypropionic acid methyl ester
  • Fmoc-L-serine methyl ester≥ 99.5% (HPLC)
  • Fmoc-L-β-hydroxyalanine methyl ester
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Ser-OMe
  • Fmoc-Ser-Ome, ≥98%
  • Methyl (((9H-fluoren-9-yl)methoxy)carbonyl)-L-serinate
  • methyl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-hydroxypropanoate
  • N-[(9-fluorenylmethoxy)carbonyl]-L-serine methyl ester
  • Methyl (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-3-hydroxypropanoate
  • L-Serine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester
  • Ceftobiprole Impurity 19
  • Tryptophan Impurity 78
  • 82911-78-2