Allylestrenol

Product Name: Allylestrenol
CAS No.: 432-60-0
Chemical Name: Allylestrenol
Synonyms: organon;Turinal;gestanin;gestanol;gestanon;gestanyn;orageston;NSC 37723;ALLYLESTRENOL;allyl-estreno
CBNumber: CB7739529
Molecular Formula: C21H32O
Formula Weight: 300.48
MOL File: 432-60-0.mol

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Allylestrenol Property

Melting point:: 79.5-80°
Boiling point:: 381.7°C (rough estimate)
Density: 0.9914 (rough estimate)
refractive index: 1.4800 (estimate)
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 14.95±0.40(Predicted)
form: Solid
color: White to Pale Yellow
Merck: 14,291
CAS DataBase Reference: 432-60-0(CAS DataBase Reference)

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Safety

RTECS: KG7960000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: A554755
Product name: Allylestrenol
Packaging: 100mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA55289
Product name: Allylestrenol
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Chem-Impex

Product number: 28191
Product name: Allylestrenol,97-102%(assay)
Purity: 97-102%(assay)
Packaging: 250MG
Price: $44.8
Updated: 2021/12/16

Chem-Impex

Product number: 28191
Product name: Allylestrenol,97-102%(assay)
Purity: 97-102%(assay)
Packaging: 10G
Price: $817.6
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 18468
Product name: Allylestrenol
Packaging: 5mg
Price: $950
Updated: 2021/12/16

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Allylestrenol Chemical Properties,Usage,Production

Originator

Alilestrenol ,Terapia

Uses

A synthetic steroid with progestational activity.

Uses

Allylestrenol, is a synthetic sexualsteroid, that is used worldwide in case of endangered pregnancies.

Definition

ChEBI: Allylestrenol is a steroid. It derives from a hydride of an estrane.

Manufacturing Process

To 145 ml of dry methylamine which is cooled to -20°C 1.5 g of lithium cut to small pieces are added. To the solution which is blue in color after 10-20 min, a solution of 3.0 g of oestradiol-3-methylether in 145 ml of absolute ether is added drop wise. Subsequently the reaction mixture is stirred at -10°C for 40 h, after which 50 ml of absolute ethanol are added. Then the methylamine is distilled off at law pressure.
To the remaining solution 50 ml of ether and 50 ml of water are added. The water layer is separated and extracted with ether. The ethereal layer is washed with a 2 N hydrochloric acid solution, subsequently with a saturated sodium bicarbonate solution, and then with water. The ethereal solution is dried and evaporated to dryness. The resulting crude reaction product is dissolved in a mixture of benzene and petroleum ether (1:3) and chromatographed over aluminium oxide. The δ4-17β-hydroxy-oestrene obtained after chromatographic purification has a melting point of 80°-90°C and 95°-100°C after repeated crystallization from petroleum ether.
A solution of 13.2 g of chromium trioxide in a mixture of 120 ml of water and 20 ml of acetic acid is added, with stirring, to a solution of 20 g of δ4-17β- hydroxy-oestrene in 400 ml of benzene. Subsequently the reaction mixture is vigorously stirred at room temperature for 16 h, after which the benzene layer is separated.
The remaining aqueous layer is extracted a few times with benzene and the benzene extracts collected are then added to the separated benzene layer. The benzene extracts are successively washed with dilute sulfuric acid and water and then evaporated to dryness. The residue is crystallized from acetone, and the δ4-17β-oxo-oestrene, melting point 114°-116°C is obtained. To a mixture of 22.4 ml of absolute ether and 1.84 g of magnesium, a mixture of 2.72 ml of allyl bromide and 2.72 ml of absolute ether is added in nitrogen atmosphere. Subsequently a solution of 2 g of δ4-17β-oxo-oestrene in 30 ml of absolute ether is added to this reaction mixture, after which the whole is stirred for 4 h. Then the reaction mixture is poured into acidified ice water. The aqueous mixture is extracted with ether; the ether layer is separated, washed with water, dried over sodium sulfate and evaporated to dryness. The residue is recrystallized from a mixture of ether and petroleum ether, giving δ4-17β-hydroxy-17α-allyl-oestrene, melting point 79.5°-80°C.

Therapeutic Function

Progestin; Antiandrogen

Allylestrenol Preparation Products And Raw materials

Raw materials

Preparation Products

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Allylestrenol Suppliers

Americas 1 Canada 1 China 195 Czech Republic 1 Europe 3 France 1 Germany 3 India 47 Italy 2 Japan 2 Nigeria 1 South Korea 2 United Kingdom 7 United States 28 Global 294

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View Lastest Price from Allylestrenol manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: Allylestrenol 432-60-0
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000
Release date: 2023-07-27

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Allylestrenol 432-60-0
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-11-13

Wuhan Cell Pharmaceutical Co., Ltd

Product: Allylestrenol 432-60-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2023-05-17

432-60-0, AllylestrenolRelated Search:

Thiophanate-methyl Methyl acetate Kresoxim-methyl Methylparaben Bensulfuron methyl METSULFURON METHYL Methyl acrylate Gestonorone 17-Methyltestosterone Voglibose Methyl Methyl bromide Parathion-methyl ETHYLESTRENOL ESTRENONE ESTREN Allylestrenol Allylestrenol Impurity B

17-allyl-estr-4-en-17-beta-o

17-allylestr-4-en-17-beta-ol

17-alpha-allyl-17-beta-hydroxy-4-estrene

17-alpha-allyl-17-beta-hydroxy-delta(sup4)-estren

17-alpha-allyl-3-deoxy-19-nortestosterone

17-alpha-allyl-4-estren-17-beta-ol

17-alpha-allyl-4-oestrene-17-beta-ol

17-alpha-allylestr-4-en-17-beta-ol

17-alpha-allylhydroxy-19-nor-4-androstene

17-hydroxy-17-alpha-allyl-4-estrene

21-methylene-19-nor-17-alpha-preg-4-en-17-o

21-methylene-19-nor-17-alpha-preg-4-en-17-ol

ALLYLESTRENOL

orageston

organon

17-Allyl estr-4-en-17β-ol

17α-Allyl-17β-hydroxy-D4-estren

17α-Allyl-4-oestren-17β-ol

17α-Allylestrenol

Estr-4-en-17b-ol, 17-allyl- (6CI, 8CI)

Estr-4-en-17-ol, 17-(2-propenyl)-, (17β)-

NSC 37723

Turinal

4-ESTREN-17-ALPHA-ALLYL-17-BETA-OL

13-methyl-17-prop-2-enyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1h-cyclopenta[a]phenanthren-17-ol

17-alpha-allyloestr-4-en-17-beta-ol

3-deoxy-17-alpha-allyl-19-nortestosterone

allyl-estreno

allyloestrenol

gestanin

gestanol

gestanon

gestanyn

1-(1,2,3,4,5,6,7,8,9,10,11,12,14,15-tetradecahydrocyclopenta[a]phenanthren-13-yl)-3-buten-1-ol

Estr-4-en-17-ol, 17-(2-propen-1-yl)-, (17β)-

Allylestrenol USP/EP/BP

AllylestrenolQ: What is Allylestrenol Q: What is the CAS Number of Allylestrenol Q: What is the storage condition of Allylestrenol Q: What are the applications of Allylestrenol

USP grade Allyl estrenol API

Allylestrenol Estrogen Hormone Raw Powder

4-ESTREN-17α-ALLYL-17β-OL

Estr-4-en-17-ol, 17-(2-propenyl)-, (17b)-

F9(3-keto-4-aza-5Α-androst-17Β-tert-butyramide)

432-60-0

C21H32O

Steroid and Hormone

Inhibitors

Medicine intermediate