N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE

Product Name: N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE
CAS No.: 218796-15-7
Chemical Name: N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE
Synonyms: Reaxys ID: 22644225;N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide;N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE;Acetamide, N-(2-chloro-6-fluoro-3-nitrophenyl)-
CBNumber: CB7745049
Molecular Formula: C8H6ClFN2O3
Formula Weight: 232.6
MOL File: Mol file

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N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Property

Boiling point:: 375.2±42.0 °C(Predicted)
Density: 1.545±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 12.19±0.70(Predicted)
Appearance: Off-white to brown Solid

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Safety

HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 312321
Product name: N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
Packaging: 250.00mg
Price: $25
Updated: 2026/05/19

Matrix Scientific

Product number: 312321
Product name: N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
Packaging: 1.00g
Price: $87
Updated: 2026/05/19

Matrix Scientific

Product number: 312321
Product name: N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
Packaging: 5.00g
Price: $419
Updated: 2026/05/19

Synthonix

Product number: C47905
Product name: N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
Purity: 95+%
Packaging: 100mg
Price: $23
Updated: 2026/05/06

Synthonix

Product number: C47905
Product name: N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide
Purity: 95+%
Packaging: 250mg
Price: $29
Updated: 2026/05/06

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N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Chemical Properties,Usage,Production

Synthesis

343-73-7

218796-15-7

Step 2: Preparation of N-(2-chloro-6-fluoro-3-nitrophenyl)acetamide. Sodium nitrate (4.53 g, 53.3 mmol) was dissolved in water (5 mL) and slowly added dropwise to a stirred solution of N-(2-chloro-6-fluorophenyl)acetamide (5 g, 26.7 mmol) in concentrated sulfuric acid (10 mL). After dropwise addition, the resulting yellow solution was stirred at 0 °C for 30 min, then warmed up to room temperature and continued stirring for 12 hours. Upon completion of the reaction, the mixture was poured into water (~250 mL) and the precipitated solid was collected by vacuum filtration. The crude product was purified by recrystallization from acetonitrile to give the title compound in the form of a light brown solid (3.2 g, 49% yield). The product was characterized as follows: 1H NMR (400 MHz, DMSO-d6) δ 10.07 (s, 1H), 8.12 (dd, J = 9.2, 5.0 Hz, 1H), 7.70-7.55 (m, 1H), 2.12 (s, 3H); ESIMS m/z 233 ([M + H]+).

References

[1] Patent: US2018/98541, 2018, A1. Location in patent: Paragraph 1669
[2] Patent: WO2012/85127, 2012, A1. Location in patent: Page/Page column 40
[3] Patent: US2012/322803, 2012, A1. Location in patent: Page/Page column 18

N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE Suppliers

China 16 India 1 United Kingdom 1 United States 3 Global 21

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218796-15-7, N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDERelated Search:

N-([1,1':3',1''-terphenyl]-5'-yl)-9,9-dimethyl-9H-fluoren-2-amine MethanesulfonaMide, N-[4-[2-(forMylaMino)acetyl]-5-Methoxy-2-phenoxyphenyl]- M348 N-(4-CHLORO-2-PYRIDINYL)-ACETAMIDE MethanesulfonaMide, N-[4-[2-(forMylaMino)acetyl]-5-hydroxy-2-phenoxyphenyl]- Cyclopentanecarboxamide, N-(1-ethyl-1H-pyrazol-4-yl)- N-(3-FORMYL-4-PYRIDINYL)-2,2-DIMETHYLPROPANAMIDE 3-(Acetylamino)-5-bromopyridine N-(4-hydroxyphenyl)-2-methoxyacetamide

N1-(2-CHLORO-6-FLUORO-3-NITROPHENYL)ACETAMIDE

N-(2-Chloro-6-fluoro-3-nitrophenyl)acetamide

Reaxys ID: 22644225

Acetamide, N-(2-chloro-6-fluoro-3-nitrophenyl)-

218796-15-7